Table 1 Demographic and clinical characteristics of SLE patients
Depression(N = 200) | Non-depression(N = 125) | Total | χ2/ t | p value | Anxiety(N = 177) | Non-anxiety(N = 148) | Total | χ2/ t | p value | |
|---|---|---|---|---|---|---|---|---|---|---|
Age | 44.57 ± 11.78 | 44.42 ± 12.12 | 44.51 ± 11.89 | 0.113 | 0.910 | 43.87 ± 11.92 | 45.28 ± 11.86 | 44.51 ± 11.89 | -1.062 | 0.289 |
Gender | 0.263 | 0.608 | 0.042 | 0.873 | ||||||
Male | 13(0.07) | 10(0.08) | 23(0.07) | 13(0.07) | 10(0.07) | 23(0.07) | ||||
Female | 187(0.94) | 115(0.92) | 302(0.93) | 164(0.93) | 138(0.93) | 138(0.42) | ||||
Educational levels | 0.141 | 0.707 | 0.689 | 0.407 | ||||||
High school degree or less | 121(0.61) | 73(0.58) | 194(0.60) | 102(0.58) | 92(0.62) | 92(0.28) | ||||
Bachelor's degree or above | 79(0.40) | 52(0.42) | 131(0.40) | 75(0.42) | 56(0.38) | 56(0.17) | ||||
Annual household income | 8.020 | 0.005 | 2.170 | 0.414 | ||||||
Less than 50,000 | 147(0.74) | 73(0.58) | 220(0.68) | 126(0.71) | 94(0.64) | 94(0.29) | ||||
More than 50,000 | 53(0.27) | 52(0.42) | 105(0.32) | 51(0.29) | 54(0.36) | 54(0.17) | ||||
Disease activity | 22.790 | 0.000 | 32.996 | 0.000 | ||||||
Inactive-mild active | 104(0.52) | 98(0.78) | 202(0.62) | 85(0.48) | 117(0.79) | 202(0.62) | ||||
Moderate-severe active | 96(0.48) | 27(0.22) | 123(0.38) | 92(0.52) | 31(0.21) | 123(0.38) | ||||
SLEDAI 2000 score | 13.61 ± 14.93 | 6.78 ± 5.16 | 10.98 ± 12.58 | 4.924 | 0.000 | 14.68 ± 15.63 | 6.56 ± 4.46 | 10.98 ± 12.58 | 6.110 | 0.000 |
Anti-dsDNA antibody | ||||||||||
Positive | 20 (0.10) | 7 (0.06) | 27 (0.08) | 1.955 | 0.215 | 19 (0.11) | 8 (0.05) | 27 (0.08) | 3.005 | 0.106 |
Negative | 180 (0.9) | 118 (0.94) | 298 (0.92) | 158 (0.89) | 140 (0.95) | 298 (0.92) | ||||
Time of onset | 0.250 | 0.875 | 0.381 | 0.571 | ||||||
Within 5 years | 99(0.50) | 63(0.50) | 162(0.50) | 91(0.51) | 71(0.48) | 162(0.5) | ||||
More than 5 years | 101(0.51) | 62(0.50) | 163(0.50) | 86(0.49) | 77(0.52) | 77(0.24) | ||||
History of smoking | 0.062 | 0.438 | 3.436 | 0.064 | ||||||
Yes | 8(0.04) | 3(0.02) | 11(0.03) | 9(0.05) | 2(0.01) | 2(0.01) | ||||
No | 192(0.96) | 122(0.98) | 314(0.97) | 168(0.95) | 146(0.99) | 146(0.45) | ||||
History of drinking | 0.628 | 0.428 | 1.359 | 0.238 | ||||||
Yes | 6(0.03) | 2(0.02) | 8(0.02) | 6(0.03) | 2(0.01) | 2(0.01) | ||||
No | 194(0.97) | 123(0.98) | 317(0.98) | 171(0.97) | 146(0.99) | 146(0.45) | ||||
Clinical manifestation* | 3.511 | 0.898 | 4.299 | 0.829 | ||||||
Skin and mucosaa | 54(0.27) | 29(0.23) | 83(0.26) | 0.584 | 0.445 | 46(0.26) | 37(0.25) | 83(0.26) | 0.041 | 0.839 |
Musculoskeletalb | 58(0.29) | 18(0.14) | 76(0.23) | 9.152 | 0.002 | 50(0.28) | 26(0.18) | 76(0.23) | 5.133 | 0.023 |
Hematologicalc | 33(0.17) | 18(0.14) | 51(0.16) | 0.256 | 0.613 | 34(0.19) | 17(0.11) | 51(0.16) | 3.633 | 0.057 |
Lupus nephritisd | 43(0.22) | 17(0.14) | 60(0.18) | 3.189 | 0.074 | 39(0.22) | 21(0.14) | 60(0.18) | 3.295 | 0.069 |
Neuropsychiatrice | 87(0.44) | 33(0.26) | 120(0.37) | 9.658 | 0.002 | 83(0.47) | 37(0.25) | 120(0.37) | 16.587 | 0.000 |