Table 1 Analysis variables in a subsample of the Genetic Links to Anxiety and Depression (GLAD) study participants (n = 2890) who received psychological therapy (cognitive behavioural therapy or counseling) for major depressive disorder, generalised anxiety disorder, or phobic/panic disorders

Self-reported change

 Much worse

59 (2.6%)

11 (1.8%)

70 (2.4%)

 A little worse

85 (3.7%)

28 (4.6%)

113 (3.9%)

 No change

465 (20.4%)

161 (26.6%)

626 (21.7%)

 A little better

970 (42.5%)

246 (40.6%)

1216 (42.1%)

 Much better

705 (30.9%)

160 (26.4%)

865 (29.9%)

Age at signup

 Mean (SD)

38.1 (13.5)

43.8 (13.5)

39.3 (13.7)

 Range

16.4–79.9

17.0–77.9

16.4–79.9

Age during therapy

 Mean (SD)

37.1 (13.2)

42.5 (13.2)

38.3 (13.4)

 Range

18.0–79.0

18.0–78.0

18.0–79.0

Ethnicity

 Arab

2 (0.1%)

0 (0.0%)

2 (0.1%)

 Asian or asian british

18 (0.8%)

9 (1.5%)

27 (0.9%)

 Black or black british

8 (0.4%)

1 (0.2%)

9 (0.3%)

 Mixed

64 (2.8%)

7 (1.2%)

71 (2.5%)

 Other

16 (0.7%)

10 (1.7%)

26 (0.9%)

 White

2172 (95.3%)

578 (95.5%)

2750 (95.3%)

 Missing data

4

1

5

University degree

 No

804 (35.8%)

232 (39.1%)

1036 (36.5%)

 Yes

1443 (64.2%)

361 (60.9%)

1804 (63.5%)

 Missing data

37

13

50

Age of onset

 Mean (SD)

18.0 (8.7)

22.1 (11.6)

18.9 (9.5)

 Range

5.0–61.0

5.0–61.0

5.0–61.0

 Missing data

136

59

195

Number of episodes

 Mean (SD)

9.0 (3.7)

9.4 (3.7)

9.1 (3.7)

 Range

1.0–13.0

1.0–13.0

1.0–13.0

 Missing data

548

147

695

Number of comorbidities

 Mean (SD)

1.4 (1.3)

1.3 (1.3)

1.4 (1.3)

 Range

0.0–6.0

0.0–5.0

0.0–6.0

Personality disorder score

 Mean (SD)

8.1 (3.5)

8.0 (3.6)

8.1 (3.5)

 Range

0.0–23.0

0.0–23.0

0.0–23.0

 Missing data

1

0

1

First therapy

 No

1989 (87.5%)

510 (84.4%)

2499 (86.9%)

 Yes

284 (12.5%)

94 (15.6%)

378 (13.1%)

 Missing data

11

2

13

Years since therapy at followup

 Mean (SD)

2.4 (2.4)

2.8 (2.7)

2.5 (2.5)

 Range

0.0–10.0

0.0–10.0

0.0–10.0

Main diagnosis

 Major depressive disorder

1329 (58.2%)

382 (63.0%)

1711 (59.2%)

 Generalised anxiety disorder

754 (33.0%)

169 (27.9%)

923 (31.9%)

 Phobia (various)

42 (1.8%)

0 (0.0%)

42 (1.5%)

 Social anxiety disorder

102 (4.5%)

40 (6.6%)

142 (4.9%)

 Panic disorder

57 (2.5%)

15 (2.5%)

72 (2.5%)

Therapy type

 One-to-one CBT

949 (41.5%)

262 (43.2%)

1211 (41.9%)

 One-to-one counselling

1199 (52.5%)

284 (46.9%)

1483 (51.3%)

 Group CBT

114 (5.0%)

48 (7.9%)

162 (5.6%)

 Group counselling

22 (1.0%)

12 (2.0%)

34 (1.2%)

Concurrent medications

 No

514 (22.6%)

151 (25.3%)

665 (23.2%)

 Yes

1759 (77.4%)

447 (74.7%)

2206 (76.8%)

 Missing data

11

8

19

Regular therapeutic activity

 No

572 (25.9%)

218 (37.7%)

790 (28.3%)

 Yes

1636 (74.1%)

361 (62.3%)

1997 (71.7%)

 Missing data

76

27

103