Fig. 1

The cumulative incidences of appendicitis in both groups. CLZ, the clozapine exposure group; non-CLZ, the clozapine non-exposure group. Lines under the curve indicate censored cases; lines on the curve indicate appendicitis onset cases. a shows the cumulative incidence of appendicitis in the clozapine exposure group starting from the initiation of clozapine administration, and b shows the cumulative incidences of appendicitis in both groups starting from the initial visit. In the former, dropout was defined as withdrawal of clozapine administration or discontinuation of follow-up, and in the latter, dropout was defined as discontinuation of follow-up