Table 2 Patient characteristics of the appendicitis cases in both groups

Sex, Man

4 (40%)

2 (40%)

2 (40%)

1.000

Age at the onset of appendicitis (years old)

25.5 (20.8–38.8)

23.0 (16.7–28.6)

30.7 (24.1–59.9)

.117

Total daily dose of antipsychotics equivalent to chlorpromazine at the onset of appendicitis (mg)

770 (381–1172)

900 (750–1500)

425 (200–952)

.076

Age at the start of clozapine administration (years old)

-

20.9 (15.9–26.7)

-

-

Length of disease duration at the start of clozapine administration (years)

-

3.8 (1.3–8.4)

-

-

Duration of clozapine administration (months)

-

16.7 (10.3–28.5)

-

-

Maximum administration dose of clozapine (mg)

-

425 (250–600)

-

-

Dose of clozapine at the onset of appendicitis (mg)

-

400 (350–600)

-

-

Withdrawal of clozapine administration due to adverse events

-

0 (0%)

-

-

Age at the start of treatment for schizophrenia (years old)

18.4 (14.9–22.7)

16.1 (14.6–18.7)

21.6 (16.3–31.7)

.117

Age at the first visit to our hospital (years old)

21.5 (16.7–31.2)

19.1 (15.7–25.8)

26.1 (18.3–41.5)

.175

Length of the disease duration (years)

6.0 (4.3–17.6)

5.2 (2.2–10.8)

7.5 (4.8–32.0)

.251

Length of the observation period (years)

4.4 (1.8–8.7)

2.1 (1–3.8)

7.3 (4.4–18.5)

.028

Coexistence of diabetes mellitus

0 (0%)

0 (0%)

0 (0%)

-

Regular user of laxatives

7 (70%)

5 (100%)

2 (40%)

.038

Regular user of anticholinergic drugs

2 (20%)

0 (0%)

2 (40%)

.114

Regular user of benzodiazepines

9 (90%)

5 (100%)

4 (80%)

.292

Regular user of corticosteroids

1 (10%)

1 (20%)

0 (0%)

.292

Regular user of mood stabilizers

1 (10%)

0 (0%)

1 (20%)

.292

Regular user of NaSSA

1 (10%)

1 (20%)

0 (0%)

.292

Regular user of NSAID_S

2 (20%)

1 (20%)

1 (20%)

1.000

Regular user of SSRIs/SNRIs

0 (0%)

0 (0%)

0 (0%)

-

Regular user of TCA

0 (0%)

0 (0%)

0 (0%)

-