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Table 1 Review on previous reports of ACC patients with anxiety symptoms

From: Social anxiety disorder in an adolescent with agenesis of the corpus callosum: a case report

Author (Year)

Age/Gender

Anxiety signs

Behavior problems

Other psychiatric disturbances

Intelligence level

Imaging performance

Associated with other Lesions

Russell [33] (1955)

19, Female

MMPI results: hypochondriasis; hysteria; psychasthenia

NA

depression; emotional instability; impaired concentration

Wechsler-bellevue test score: 61

complete absence of the corpus callosum

dilation of both lateral ventricles; Middle cerebral aqueduct the stenosis; the third ventricle was enlarged superiorly and posteriorly; the left cerebellar hemisphere was smaller than normal

Spak [34] (2019)

12, Male

generalized anxiety; aggression; stress

obsessive–compulsive disorder

attention deficit disorder;

unable to concentrate on completing drumming and talking

IQ 68

partial agenesis of the corpus callosum(posterior)

NA

Párraga [35] (2003)

11, Male

irrational fears; anxiety attacks; separation anxiety; poor eye contact

hyperactivity; poor impulse control; difficulties relating to other children

visual and auditory hallucinations; marked distortions of reality; sleep difficulties

IQ 85

agenesis of the corpus callosum(unspecified)

colpocephaly

10, Female

agitated movement

hyperactivity; temper outbursts; oppositional; lying; stealing; destruction

emotionality; sleep difficulties

IQ 102

partial agenesis of the corpus callosum (the rostrum and the body)

colpocephaly

David [24] (1993)

33, Male

fear; acute anxiety episodes

set fire; attack neighbors

mannerisms; hallucinations; delusions

IQ 78

partial agenesis of the anterior part of the corpus callosum

NA

Ernst [36] (1999)

15, Female

alexithymia; chronical pain; stressful events lead to an increase in pain

NA

NA

NA

agenesis of the corpus callosum(unspecified)

Chiari II Malformation; hydrocephalus

  1. Abbreviations: MMPI Minnesota Multiphasic Personality Inventory, NA Not available, IQ Intelligence quotient