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Table 4 Associations of plasma complements and CRP with age and BMI in the MDD group, HC group, and all participants

From: Plasma complement C3 and C3a are increased in major depressive disorder independent of childhood trauma

 

C3

C3a

C1q

CRP

  

MDD*

HC*

ALL#

MDD*

HC*

ALL#

MDD*

HC*

ALL#

MDD*

HC*

ALL#

Age

rs/β

-0.026

0.306

0.117

0.042

0.099

-0.086

0.132

0.103

0.070

0.170

-0.085

0.054

 

P

0.861

0.041

0.254

0.775

0.519

0.390

0.364

0.501

0.513

0.244

0.579

0.566

BMI

rs/β

0.405

0.170

0.261

0.385

0.055

0.233

0.146

0.216

0.182

0.533

0.417

0.431

 

P

0.004

0.265

0.015

0.006

0.718

0.026

0.318

0.154

0.101

 < 0.001

0.004

 < 0.001

  1. * Spearman correlational analysis was used for the MDD and HC group, and spearman r (rs) is present in the table
  2. # Multiple linear regression (MLR) was used for correlational analysis in all participants to control for the diagnosis, and standardized beta (β) is present in the table; plasma complements and CRP were LN-transformed in MLR. C3 Complement component 3, C3a Complement component 3a, C1q Complement component 1q, CRP C-reactive protein, MDD Major depressive disorder, HC Health control, ALL All participants
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BMC Psychiatry

ISSN: 1471-244X

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