BMC Psychiatry

Table 5 Associations of plasma complements and CRP with childhood trauma experiences in the MDD group, HC group, and all participants

From: Plasma complement C3 and C3a are increased in major depressive disorder independent of childhood trauma

		C3*			C3a*			C1q*			CRP*
		MDD	HC	ALL	MDD	HC	ALL	MDD	HC	ALL	MDD	HC	ALL
CTQ total score	β	-0.040	-0.339	-0.176	0.121	-0.191	0.056	0.074	-0.232	-0.061	-0.001	-0.112	-0.046
	P	0.773	0.019	0..146	0.391	0.220	0.641	0.611	0.130	0.634	0.995	0.441	0.683
Emotional Abuse	β	-0.010	-0.310	-0.102	0.142	-0.230	0.084	0.026	-0.342	-0.123	0.041	-0.052	0.008
	P	0.946	0.033	0.377	0.320	0.138	0.458	0.862	0.023	0.309	0.755	0.724	0.941
Emotional Neglect	β	-0.082	-0.350	-0.216	0.167	-0.130	0.116	0.051	-0.078	-0.002	-0.050	-0.113	-0.077
	P	0.567	0.015	0.087	0.244	0.406	0.351	0.736	0.613	0.989	0.704	0.441	0.516
Physical Abuse	β	0.017	-0.245	-0.092	0.105	-0.169	0.036	0.046	-0.226	-0.081	-0.066	0.017	-0.040
	P	0.902	0.096	0.395	0.456	0.277	0.738	0.755	0.141	0.475	0.610	0.986	0.689
Physical Neglect	β	-0.028	-0.350	-0.163	0.076	-0.040	0.054	0.041	-0.193	-0.053	0.041	-0.162	-0.025
	P	0.839	0.015	0.182	0.596	0.801	0.653	0.784	0.210	0.684	0.750	0.264	0.829
Sexual Abuse	β	-0.083	-0.100	-0.091	-0.148	-0.233	-0.168	0.275	-0.082	0.085	0.044	-0.172	-0.060
	P	0.559	0.499	0.360	0.302	0.129	0.083	0.061	0.592	0.414	0.735	0.231	0.515

^* Multiple linear regression (MLR) was used for correlational analysis to control age and BMI in the MDD and HC group, to control age, BMI, and diagnosis in all participants; plasma complements and CRP were LN-transformed in MLR
C3 Complement component 3, C3a Complement component 3a, C1q Complement component 1q, CRP C-reactive protein, MDD Major depressive disorder, HC Health control, ALL All participants, CTQ Childhood trauma questionnaire

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