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Table 3 Odds Ratio and 95% confidence intervals for body mass index, fat mass, waist, WHR and abdominal fat trajectories with cognitive impairment and cognitive decline

From: Obesity marker trajectories and cognitive impairment in older adults: a 10-year follow-up in Taichung community health study for elders

  

Cognitive impairment OR (95% CI)

Cognitive decline (> 75 Pctl) OR (95% CI)

n

Age and sex adjusted model

Multivariate model 1

Multivariate model 2

Age and sex adjusted model

Multivariate model 1

Multivariate model 2

BMI trajectories

 Cluster 1

96

1.00

1.00

1.00

1.00

1.00

1.00

 Cluster 2

219

0.59 (0.35, 1.01)

0.58 (0.34, 1.01)

0.70 (0.38, 1.29)

0.85 (0.49, 1.46)

0.84 (0.48, 1.46)

0.87 (0.49, 1.55)

 Cluster 3

215

0.55 (0.32, 0.94)*

0.54 (0.31, 0.94)*

0.59 (0.32, 1.09)

0.83 (0.48, 1.45)

0.84 (0.48, 1.48)

0.86 (0.48, 1.55)

 Cluster 4

96

0.52 (0.27, 0.99)*

0.49 (0.25, 0.95)*

0.65 (0.31, 1.34)

0.99 (0.52, 1.87)

0.98 (0.51, 1.89)

0.98 (0.50, 1.93)

Fat mass trajectories

 Cluster 1

69

1.00

1.00

1.00

0.67 (0.34, 1.31)

0.65 (0.32, 1.30)

0.63 (0.31, 1.29)

 Cluster 2

184

0.35 (0.18, 0.68)**

0.37 (0.19, 0.71)**

0.41 (0.20, 0.85)*

0.65 (0.40, 1.05)

0.68 (0.42, 1.11)

0.65 (0.39, 1.08)

 Cluster 3

179

0.54 (0.29, 1.01)

0.56 (0.30, 1.06)

0.54 (0.27, 1.08)

1.00

1.00

1.00

 Cluster 4

194

0.57 (0.31, 1.04)

0.58 (0.31, 1.07)

0.65 (0.33, 1.28)

0.76 (0.48, 1.21)

0.77 (0.48, 1.23)

0.79 (0.49, 1.27)

WC trajectories

 Cluster 1

137

1.00

1.00

1.00

0.73 (0.42, 1.26)

0.68 (0.39, 1.19)

0.68 (0.38, 1.21)

 Cluster 2

158

0.68 (0.39, 1.17)

0.67 (0.39, 1.18)

0.59 (0.32, 1.09)

1.00

1.00

1.00

 Cluster 3

215

0.77 (0.47, 1.27)

0.77 (0.46, 1.28)

0.63 (0.36, 1.13)

0.71 (0.45, 1.14)

0.71 (0.44, 1.14)

0.70 (0.43, 1.13)

 Cluster 4

116

0.64 (0.35, 1.17)

0.66 (0.36, 1.21)

0.53 (0.27, 1.04)

0.60 (0.34, 1.07)

0.57 (0.31, 1.02)

0.61 (0.33, 1.13)

WHR trajectories

 Cluster 1

273

1.00

1.00

1.00

0.74 (0.41, 1.34)

0.78 (0.43, 1.43)

0.70 (0.38, 1.30)

 Cluster 2

207

0.68 (0.43, 1.08)

0.72 (0.45, 1.15)

0.70 (0.41, 1.18)

0.41 (0.22, 0.78)**

0.45 (0.24, 0.87)*

0.43 (0.22, 0.85)*

 Cluster 3

64

0.68 (0.35, 1.30)

0.70 (0.36, 1.35)

0.60 (0.29, 1.25)

1.00

1.00

1.00

 Cluster 4

82

0.54 (0.30, 0.98)*

0.55 (0.30, 1.02)

0.43 (0.22, 0.84)*

0.78 (0.38, 1.59)

0.84 (0.41, 1.75)

0.75 (0.35, 1.58)

Abdominal fat trajectories

 Cluster 1

158

1.00

1.00

1.00

0.98 (0.59, 1.61)

0.94 (0.57, 1.57)

0.89 (0.53, 1.50)

 Cluster 2

183

0.47 (0.29, 0.78)**

0.50 (0.30, 0.83)**

0.44 (0.26, 0.77)**

1.00

1.00

1.00

 Cluster 3

218

0.37 (0.22, 0.65)***

0.39 (0.23, 0.69)**

0.33 (0.18, 0.61)***

0.81 (0.50, 1.30)

0.87 (0.53, 1.41)

0.83 (0.51, 1.37)

 Cluster 4

67

0.60 (0.31, 1.15)

0.55 (0.28, 1.06)

0.39 (0.18, 0.82)*

0.63 (0.31, 1.27)

0.59 (0.28, 1.21)

0.61 (0.29, 1.27)

  1. BMI Body mass index, WC Waist circumference, WHR Waist-to-hip ratio; *: p < 0.05; **: p < 0.01; ***: p < 0.001
  2. 1Multivariate adjustment for age, sex, exercising program, education, marital status, BMI, smoking, alcohol drinking, and physical activity
  3. 2Multivariate adjustment for age, sex, exercising program, education, marital status, BMI, smoking, alcohol drinking, physical activity, hypertension, diabetes mellitus, heart disease, hyperlipidemia, stroke, cancer, fall history, sleep disturbance, frailty and baseline cognitive status