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Table 1 Target values of trough levels of risperidone and aripiprazole

From: The effect of therapeutic drug monitoring of risperidone and aripiprazole on weight gain in children and adolescents: the SPACe 2: STAR (trial) protocol of an international multicentre randomised controlled trial

Antipsychotic drug

Laboratory target

Target values

Risperidone

Sum (risperidone + 9-hydroxyrisperidone) trough level

Therapeutic window: 3.5–7 μg/L

Optimal target: 5.25 μg/L

Aripiprazole

Sum (aripiprazole + dehydro-aripiprazole) trough level

Therapeutic window: 13.6–60 μg/L