Table 1 Overview of collected data and phenotyping instruments
| Â | Instrument(s) | Data source | Cases | Controls |
|---|---|---|---|---|
Core questionnaire | ||||
 Socio-demographics |  | SR/I | x | x |
 Complications during pregnancy and birth |  | SR/I/MR | x | x |
 Seasonality |  | SR/I | x | x |
 Urbanicity |  | SR/I | x | x |
 Migration |  | SR/I | x | x |
 History of drug use |  | SR/I/MR | x | x |
 History of mental illness |  | SR/I |  | x |
 Basic clinical data |  | SR/I/MR | x |  |
 Health data |  | SR/I/MR | x | x |
 Childhood adversity | CTQ | SR | x | x |
 Lifetime traumatic events | ETIa,b | SR | x | x |
 Psychotic experiences in the population | LSHS-R, PDI-k21, PCL-5a | SR |  | x |
 Schizotypy | SPQ-BR | SR |  | x |
 Subclinical (hypo)mania | MDQ | SR |  | x |
 Suicidality | SBQ-R | SR | x | x |
 Resilience | RS-13, BRS | SR | x | x |
 Social support | FSozU-k14 | SR | x | x |
 Anxiety & Depression | PHQ-4 | SR | x | x |
 Subjective wellbeing | PWI-A | SR | x | x |
Neurocognitive assessment | ||||
 Sensorimotor function, comprehension | MOT | TB | x | x |
 Processing & psychomotor speed | RTI | TB | x | x |
 Working Memory & strategy | SWM | TB | x | x |
 Verbal memory and new learning | VRM | TB | x | x |
 Visual episodic memory | PAL | TB | x | x |
 Planning | OTS | TB | x | x |
 Sustained Attention | RVP | TB | x | x |
 Emotion Recognition | ERT | TB | x | x |
 Multitasking | MTT | TB | x | x |
 Handedness | EHI-SF | SR | x | x |
Clinical assessment | ||||
 Symptom profile | PANSS | CR | x |  |
 Symptom Severity | CGI-S | CR | x |  |
 Psychopathology | SCL-90-R | SR | x | x |
 Global functioning | GAF | CR | x |  |
 Disability and functional outcomes | WHODAS 2.0 | SR/I | x | x |