The Precision in Psychiatry (PIP) study: Testing an internet-based methodology for accelerating research in treatment prediction and personalisation

Table 2 Baseline clinical characteristics

Sample Characteristics	iCBT			Antidepressant				t / X² (df)	p
Sample Characteristics	N	%	Median (SD)	N	%	Median (SD)
No. of Current Diagnosis	502			92				21.67 (2)	< 0.001
None	155	30.88		8	8.70
One	183	36.45		37	40.22
> One	164	32.67		47	51.09
Types of Diagnoses^a	502			92				9.57 (5)	0.09
None	155	30.88		8	8.70
Depression	245	48.80		70	76.09
GAD	209	41.63		48	52.17
Panic Disorder	25	4.98		4	4.35
PTSD	20	3.98		13	14.13
OCD	23	4.58		4	4.35
Others	41	8.17		13	14.13
Family with Mental Disorders	502			92				1.80 (3)	0.62
None	207	41.24		32	34.78
One	156	31.08		30	32.61
Two	81	16.14		16	17.39
≥ Three	58	11.55		14	15.22
No. of Lifetime Episodes	494			91				11.09 (2)	0.004
< 2	53	10.73		7	7.69
2–5	246	49.80		31	34.07
> 5	195	39.47		53	58.24
Age of onset (years)	492			92				8.68 (2)	0.01
Childhood (1–12)	86	17.48		23	24.47
Teenage (13–17)	211	42.89		47	50.00
Adulthood (18–70)	195	39.63		22	23.40
Current episode length (days)	457		199 (2557)	84			190 (2463)	0.05 (539)	0.96
History of Past Treatment	502			92				5.95 (3)	0.11
Never Before	224	44.62		30	31.91
Psychotherapy & Medication	115	22.91		28	29.79
Medication only	82	16.33		14	14.89
Psychotherapy only	81	16.14		20	21.28
Treatment Expectation (0–9)	502		5 (2.04)	92			5 (1.89)	-1.95 (592)	0.05

^aTypes of Diagnoses: The total number of diagnoses type exceeds the sample size of baseline completers (i.e., participants have the option to pick more than one diagnosis)
Outliers were not excluded in the descriptive analyses of clinical characteristics

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