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Table 2 The group analyses of the clinical characteristic according to assessment

From: Prognostic prediction of subjective cognitive decline in major depressive disorder based on immune biomarkers: a prospective observational study

  

SCD (n = 28)

NSCD (n = 22)

P value

Age

Mean (SD)

28.25 ± 8.195

26.05 ± 5.59

0.295

Gender

Male, n (%)

7

4

 

Female, n (%)

21

18

 

Education level

Mean (SD)

15.07 ± 3.615

15 ± 2.12

0.934

Marital status

Single, n (%)

15

12

0.928

Married, n (%)

11

9

 

Divorced, n (%)

2

1

 

Employment status

Employed, n (%)

21

11

0.83

Unemployed, n (%)

7

11

 

Smoking

Yes, n (%)

24

14

0.07

No, n (%)

4

8

 

Drinking

Yes, n (%)

6

10

0.071

No, n (%)

22

12

 

Height

Mean (SD)

164.69 ± 7.79

164.35 ± 7.94

0.832

Weight

Mean (SD)

56.75 ± 10.62

55.9 ± 12.37

0.649

BMI

Mean (SD)

24.44 ± 8.62

23.14 ± 5.03

0.739

Age of MDD onset (years)

Mean (SD)

24.44 ± 8.62

23.13 ± 5.03

0.739

History of MDD episode

First episode, n (%)

15

10

0.569

Recurrent episode, n (%)

13

12

 

Total course, month

Mean (SD)

26.56 ± 33.97

37.15 ± 38.56

0.338

HRSD17 at baseline

Mean (SD)

23.68 ± 4.86

22.18 ± 4.62

0.275

HRSD17 total score reduction, %

Mean (SD)

51.87 ± 22.62

67.5 ± 20.65

0.015*

Medicine (ES/VL)

ES, n (%)

12

15

0.075

VL, n (%)

16

7

 

PDQ-D-baseline

Mean (SD)

41.11 ± 15.01

29.23 ± 12.33

0.006**

PDQ-PC

Mean (SD)

18.03 ± 5.76

13.18 ± 5.93

0.005**

PDQ-RM

Mean (SD)

16.2 ± 7.04

12.36 ± 5.49

0.041*

PDQ-PM

Mean (SD)

6.91 ± 3.63

3.86 ± 2.55

0.003**

PDQ-D-Week 8

Mean (SD)

46.21 ± 15.32

12.62 ± 7.89

0.001**

PDQ-PC

Mean (SD)

18.14 ± 5.71

5.27 ± 3.87

0.001**

PDQ-RM

Mean (SD)

20.18 ± 7.55

6.36 ± 4.16

0.001**

PDQ-PM

Mean (SD)

7.89 ± 3.33

1.00 ± 1.20

0.001**

  1. Abbreviation: SCD Subjective cognitive decline, NSCD Non-subjective cognitive decline, BMI Body mass Index, HRSD the Hamilton Depression Rating Scale-17, ES Escitalopram, VF Venlafaxine, PDQ-D the Perceived Deficits Questionnaire-depression, PC Planning/concentration, RM Retrospective memory, PM Prospective memory
  2. * Significantly difference (p < 0.05)
  3. ** Significantly difference (p < 0.01)