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Table 1 Clinical and demographic variables

From: Neurological soft signs and structural network changes: a longitudinal analysis in first-episode schizophrenia

Variables Mean (SD)

Healthy Controls

Patients (Baseline)

Patients (Follow-up)

P-value

Age (year)

24.1 (3.5)

25.6 (7.2)

/

0.52

Sex(male/female)

10/10

7/13

/

0.34

Chlorpromazine equivalents (mg/day)

/

549.3 (271.3)

443.8(137.7)

0.17

NSS

3.6 (1.6)

15.3 (6.8)

11.30 (8.31)

< 0.001a

NSS subgroups

 

Decreasing NSS (n = 10)

Persisting NSS (n = 10)

 
 

Baseline

Follow-up

Baseline

Follow-up

 

NSS

15.9 (3.9)

7.2 (3.5)

14.6 (9.2)

14 (9.5)

< 0.001b

PANSS

51.2 (9.8)

44.2 (9.9)

50.1(13.6)

52.8(22.8)

0.28b

Age at baseline

26.1 (6.5)

25.0 (8.2)

0.66

Sex(male/female)

3/7

4/6

0.64

  1. NSS Neurological soft signs, PANSS Positive and negative syndrome scale, SD Standard deviation
  2. a: p-value for the difference between healthy controls and patients at baseline
  3. b: repeated ANOVAs in two subgroups