Variables Mean (SD) | Healthy Controls | Patients (Baseline) | Patients (Follow-up) | P-value | ||
---|---|---|---|---|---|---|
Age (year) | 24.1 (3.5) | 25.6 (7.2) | / | 0.52 | ||
Sex(male/female) | 10/10 | 7/13 | / | 0.34 | ||
Chlorpromazine equivalents (mg/day) | / | 549.3 (271.3) | 443.8(137.7) | 0.17 | ||
NSS | 3.6 (1.6) | 15.3 (6.8) | 11.30 (8.31) | < 0.001a | ||
NSS subgroups | ||||||
 | Decreasing NSS (n = 10) | Persisting NSS (n = 10) |  | |||
 | Baseline | Follow-up | Baseline | Follow-up |  | |
NSS | 15.9 (3.9) | 7.2 (3.5) | 14.6 (9.2) | 14 (9.5) | < 0.001b | |
PANSS | 51.2 (9.8) | 44.2 (9.9) | 50.1(13.6) | 52.8(22.8) | 0.28b | |
Age at baseline | 26.1 (6.5) | 25.0 (8.2) | 0.66 | |||
Sex(male/female) | 3/7 | 4/6 | 0.64 |