From: The impact of antipsychotic adherence on acute care utilization
0 – 6 Months | 6 -12 Months | |||
---|---|---|---|---|
OR (95% CI) | P-value | OR (95% CI) | P-value | |
Cohort | ||||
Psychiatric Control (reference) | 1.00 | 1.00 | ||
Bipolar Disorder | 1.11 (0.86, 1.43) | 0.444 | 1.20 (0.93, 1.54) | 0.153 |
Schizophrenia | 1.28 (0.97, 1.69) | 0.078 | 1.48 (1.13, 1.95) | 0.005 |
Age | 0.99 (0.98, 1.00) | 0.004 | 0.99 (0.98, 1.00) | 0.010 |
Female | 1.22 (0.99, 1.50) | 0.069 | 1.31 (1.06, 1.61) | 0.012 |
Medicaid | 0.88 (0.67, 1.17) | 0.387 | 0.74 (0.57, 0.97) | 0.031 |
Medicare | 1.30 (0.93, 1.81) | 0.129 | 0.90 (0.65, 1.25) | 0.530 |
Diabetes | 1.08 (0.85, 1.37) | 0.538 | 1.13 (0.89, 1.42) | 0.324 |
CHF | 1.49 (0.98, 2.26) | 0.065 | 1.91 (1.27, 2.86) | 0.002 |
OSA | 0.80 (0.53, 1.22) | 0.309 | 1.08 (0.71, 1.62) | 0.726 |
Hypertension | 1.13 (0.90, 1.43) | 0.304 | 1.08 (0.86, 1.35) | 0.534 |
MI | 1.09 (0.46, 2.59) | 0.844 | 0.52 (0.21, 1.28) | 0.156 |
Cerebrovascular Disease | 0.82 (0.51, 1.30) | 0.389 | 0.99 (0.63, 1.58) | 0.981 |
COPD | 1.15 (0.86, 1.54) | 0.358 | 1.49 (1.12, 1.97) | 0.006 |
Depression | 0.93 (0.75, 1.15) | 0.482 | 0.84 (0.68, 1.03) | 0.098 |
Cancer | 1.39 (0.93, 2.08) | 0.110 | 1.33 (0.90, 1.96) | 0.159 |
Anxiety | 1.10 (0.89, 1.37) | 0.377 | 1.33 (1.08, 1.64) | 0.009 |
Dementia | 1.52 (0.88, 2.61) | 0.134 | 0.77 (0.45, 1.34) | 0.358 |
Alcohol Abuse | 1.13 (0.82, 1.56) | 0.454 | 0.99 (0.73, 1.35) | 0.946 |
Substance Abuse | 1.25 (0.99, 1.56) | 0.056 | 1.31 (1.05, 1.63) | 0.017 |
Adherence/Switch Categories | ||||
No Switch & Adherence 0.8 + (reference) | 1.00 | 1.00 | ||
No Switch & Adherence < 0.5 | 1.58 (1.07, 2.32) | 0.020 | 1.41 (0.97, 2.04) | 0.073 |
No Switch & Adherence 0.5 – 0.79 | 1.25 (0.95, 1.65) | 0.108 | 1.17 (0.89, 1.53) | 0.261 |
Switch & Adherence < 0.5 | 2.04 (0.95, 4.40) | 0.069 | 1.19 (0.57, 2.46) | 0.648 |
Switch & Adherence 0.5—0.79 | 1.43 (0.92, 2.22) | 0.115 | 1.22 (0.79, 1.88) | 0.368 |
Switch & Adherence ≥ 0.8 | 1.20 (0.82, 1.75) | 0.351 | 0.75 (0.51, 1.10) | 0.144 |
Stop | 1.63 (1.22, 2.16) | 0.001 | 1.04 (0.79, 1.38) | 0.780 |
Any Inpatient Stay Prior Year | 1.80 (1.44, 2.26) | < 0.001 | 1.07 (0.86, 1.34) | 0.556 |
Any ED Visit Prior Year | 4.31 (3.47, 5.35) | < 0.001 | 2.89 (2.33, 3.59) | < 0.001 |
7% Weight Gain | 0.91 (0.70, 1.18) | 0.463 | 0.68 (0.52, 0.87) | 0.003 |