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Table 1 Demographics and clinical characteristics of healthy control, genetic high risk, and schizophrenia in longitudinal study

From: Neurodevelopmental trajectories, polygenic risk, and lipometabolism in vulnerability and resilience to schizophrenia

 

Healthy Control (n = 39)

Genetic High Risk (n = 26)

Schizophrenia (n = 21)

Statistic values

 

Baseline

Follow-up

Baseline

Follow-up

Baseline

Follow-up

Baseline

Follow-up

Demographic characteristic

 Age at scans (year)

27.46 (7.39)

30.59 (7.44)

26 (7.29)

28.38 (6.84)

23 (8.06)

25.05 (7.77)

F = 2.4, P = 0.97

F = 3.9, P < 0.05

 Gender (male/female)

14/25

20/6

7/14

χ2 = 12.82, P < 0.05

 Duration of MRI interval (month)

29 (14.87)

22.5 (11.48)

25.43 (17.77)

F = 1.68, P = 0.19

Clinical Characteristics

 Duration of illness (months)

N/A

N/A

27.0 (38.95)

51.94 (60.27)

  

 Medication (yes/no)

N/A

N/A

18/3

19/2

  

 BPRS

18.67 (1.36)

18.77(2.15)

19.46 (2.99)

18.85(1.59)

28.14 (8.07)

23.38(6.60)

F = 31.53, P < 0.001

F = 12.47, P < 0.001

  1. Data are presented as mean (standard deviation)
  2. BPRS Brief Psychiatric Rating Scale