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Table 3 Neutropenia and leukocytosis: p value obtained by Fisher’s exact test (2 × 2 table)

From: Valproate-related neutropenia and lithium-related leukocytosis in patients treated with clozapine: a retrospective cohort study

 

Neutropenia

Leukocytosis

CLO vs. CLO + VAL

< 0.001

0.491

CLO vs. CLO + Li

0.626

< 0.001

CLO + VAL vs. CLO + Li

0.035

< 0.001

  1. Bold and underlined p values indicate a statistically significant difference
  2. Alpha is modified using modified Holm-Bonferroni procedure. The number of planned pairwise comparison is three for neutropenia and leukocytosis each; therefore, the p value of CLO + VAL vs. CLO + Li is considered to be insignificant (0.035 > 0.05/2) because this value is the second smallest across the three comparisons in neutropenia