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Table 3 Treatment effect, selection effect and preference effect on the primary outcomes of the eligible trials

From: A scoping review on two-stage randomized preference trial in the field of mental health and addiction

Trial

Publication

Treatment and comparison groups

Primary outcome(s)

Means

Treatment Effect

(for A)

Selection Effect (for A)

Preference Effect

Standardized

Preference Arm

Random Arm

Treatment Effect

(for A)

Selection Effect

(for A)

Preference Effect

A

B

A

B

1

Rokke et al. 1999 [10]

A: Behavioral therapy

B: Cognitive therapy

Depression ratings scales (HDRS, BDI, GDS) immediately, 1 m and 3 m post treatment

Data Not Available

-

-

-

-

-

-

2

Hegerl et at. 2010 [11]

A: CBT

B: Medication (sertraline)

Depression ratings scales (HDRS) at 10w a

10.84

9.30

9.32

9.48

-0.16

1.45

0.96

-0.02

0.24

0.18

Mergl et al. 2011 [12]

3

He et al. 2018 [13]

A: Parent Management Training-Oregon Model (PMTO)

B: Services as usual (SAU)

Parenting outcome (Parental Locus of Control Scale) post intervention a

113.9

119.7

116.8

111.3

-5.47

12.03

1.32

-0.29

0.64

0.07

Parenting outcome(Family Interaction Task) post intervention

2.43

1.99

2.20

2.37

-0.17

0.77

0.28

-0.34

1.55

0.57

Gewirtz et al. 2019 [14]

Youth Outcomes (The Strength and Difficulties Questionnaire) post intervention

Data Not Available

-

-

-

-

-

-

4

Le et al. 2018 [15]

A: Prolonged exposure therapy

B: Medication (sertraline)

Quality of life (EQ-5D) at 10w

0.83

0.78

0.85

0.67

0.18

-0.12

0.06

0.79

-0.50

0.25

Zoellner et al. 2019 [16]

PTSD Symptom Scale–Interview Version [PSS-I] up to 24 m post treatment

Data Not Available

-

-

-

-

-

-

5

Brenes et al. 2020

A: CBT

B: Yoga

Worry scale (PSWQ‐A) (change from baseline)

9.10

8.40

8.80

7.20

1.60

-0.96

1.54

0.21

-0.13

0.21

6

Svensson et al. 2021a [18]

Svensson et al. 2021b [19]

A: Panic Control Treatment

B:Panic focused psychodynamic therapy

Panic Disorder Severity Scale (PDSS) post treatment a

8.6

9.7

7.5

10.8

3.30

-2.22

0.23

0.64

-0.43

0.04

Panic Disorder Severity Scale (PDSS) follow-up at 24 m a

7.1

5.1

6.2

7.5

1.30

-3.53

1.93

0.24

-0.65

0.35

  1. aGreater score represents worse outcome