Factors associated with objective and subjective cognitive impairment in Chinese patients with acute major depressive disorder

Table 2 Comparison of z scores using the THINC-it tool between the MDD and HC groups

Variables	MDD (n = 75)	HC (n = 100)	Z	P	F^a	P ^a
Spotter	-0.516 ± 1.210	0.440 ± 0.732	-5.319	< 0.001^***	30.966	< 0.001^***
Symbol Check	-0.299 ± 0.940	0.094 ± 0.916	-1.040	0.298	0.028	0.868
Codebreaker	-0.400 ± 1.071	0.305 ± 0.759	-4.451	< 0.001^***	10.811	0.001
Trails	-0.072 ± 0.646	0.291 ± 0.445	-4.173	< 0.001^***	9.146	0.003
PDQ-5-D	-0.720 ± 0.919	0.539 ± 0.666	-8.034	< 0.001^***	83.273	< 0.001^***
THINC-ittotal scores	-0.348 ± 0.636	0.334 ± 0.401	-6.548	< 0.001^***	45.822	< 0.001^***

Abbreviations: MDD, major depressive disorder; HC, healthy controls; PDQ-5-D, Perceived Deficits Questionnaire for Depression–5-items. Note: F^a, P^a, F, P value after adjusting for years of education; ***, P < 0.001

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