Table 4 Discrimination ability of DuCA
From: Dual-stage cognitive assessment: a two-stage screening for cognitive impairment in primary care
| Â | Â | Â | Discrimination ability for MCI | |||||||
|---|---|---|---|---|---|---|---|---|---|---|
MCI from NC | NC | MCI | P value | Â | AUC | Cut-off | Sensitivity | Specificity | PPV* | NPV* |
Education ≤ 6 years | n = 55 | n = 53 |  | DuCA-1 | 0.83 | ≤ 5 | 90.6% | 54.6% | 66.6% | 85.3% |
 Sex (male, %) | 13, 23.6% | 12, 22.6% | 0.902 |  |  | ≤ 3 | 62.3% | 87.3% | 83.1% | 69.8% |
 Age | 65.27 ± 6.73 | 67.26 ± 7.2 | 0.140 | DuCA-T | 0.89 | ≤ 20 | 88.7% | 74.6% | 77.7% | 86.8% |
 Education years | 5.08 ± 1.31 | 4.78 ± 1.3 | 0.237 |  |  | ≤ 17.5 | 73.6% | 87.3% | 85.3% | 76.8% |
Education > 6–9 years | n = 178 | n = 169 |  | DuCA-1 | 0.86 | ≤ 6 | 90.5% | 60.1% | 69.4% | 86.4% |
 Sex (male, %) | 56, 31.5% | 52, 30.8% | 0.889 |  |  | ≤ 4 | 62.1% | 88.8% | 84.7% | 70.1% |
 Age | 65.76 ± 5.55 | 66.55 ± 6.10 | 0.21 | DuCA-T | 0.93 | ≤ 22 | 92.3% | 83.7% | 85.0% | 91.6% |
 Education years | 8.76 ± 0.51 | 8.70 ± 0.62 | 0.277 |  |  | ≤ 21 | 84.0% | 89.3% | 88.7% | 84.8% |
Education > 9–12 years | n = 329 | n = 240 |  | DuCA-1 | 0.85 | ≤ 6 | 86.7% | 66.3% | 72.0% | 83.3% |
 Sex (male, %) | 108, 32.8% | 70, 29.2% | 0.352 |  |  | ≤ 4 | 52.5% | 94.5% | 90.5% | 66.5% |
 Age | 64.50 ± 6.28 | 65.37 ± 6.21 | 0.102 | DuCA-T | 0.93 | ≤ 23 | 89.6% | 85.4% | 86.0% | 89.1% |
 Education years | 11.36 ± 0.77 | 11.25 ± 0.83 | 0.116 |  |  | ≤ 22.5 | 85.8% | 90.0% | 89.6% | 86.4% |
Education > 12 years | n = 446 | n = 171 |  | DuCA-1 | 0.84 | ≤ 6 | 81.9% | 69.7% | 73.0% | 79.4% |
 Sex (male, %) | 182, 40.8% | 72, 42.1% | 0.769 |  |  | ≤ 5 | 67.8% | 85.4% | 82.3% | 72.6% |
 Age | 65.31 ± 7.95 | 66.46 ± 7.92 | 0.109 | DuCA-T | 0.94 | ≤ 23 | 91.2% | 87.0% | 87.5% | 90.8% |
 Education years | 15.1 ± 1.81 | 14.96 ± 1.78 | 0.385 |  |  | ≤ 22 | 86.0% | 90.8% | 90.3% | 86.6% |
Total |  |  |  | DuCA-1 | 0.85 | ≤ 6 | 87.1% | 65.1% | 71.4% | 83.5% |
|  |  |  |  |  |  | ≤ 5 | 73.9% | 81.5% | 80.0% | 75.7% |
|  |  |  |  | DuCA-T | 0.93 | ≤ 22.5 | 89.6% | 85.1% | 85.7% | 89.1% |
AD from MCI | MCI | AD |  | DuCA-1 | 0.84 | ≤ 3 | 91.6% | 66.2% | 73.0% | 88.7% |
|  |  |  |  |  |  | ≤ 2 | 53.4% | 86.7% | 80.1% | 65.0% |
|  | n = 633 | n = 131 |  | DuCA-T | 0.95 | ≤ 15 | 98.5% | 80.0% | 83.1% | 98.2% |
|  |  |  |  |  |  | ≤ 13 | 85.5% | 90.8% | 90.3% | 86.2% |