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Table 1 Follow up times, type (feminizing/ masculinizing) of prescribed and continued/ discontinued hormonal gender reassignment, timing and duration of contacting gender identity services and using hormonal GR, and specialist level psychiatric treatment contact among subjects who continued/ discontinued their established hormonal gender reassignment. Distributions (%, n/N) of the categorical variables and mean(sd) of the continuous variables, and their comparison between the intake cohorts

From: Discontinuing hormonal gender reassignment: a nationwide register study

 

All, index date

Index date

Index date

Index date

p (between cohorts)

1996–2019

1996–2005

2006–2012

2013–2019

Follow-up-time from index contact to 31.12.21, mean(sd) in years

     

8.5 (4.3)

20.3 (4.0)

11.7 (1.6)

6.0 (1.6)

Specially reimbursed hormonal GR (n)

1359

102

438

819

 

Specially reimbursed hormonal GR was (% (n/N)

    

0.002*

 towards female

34.4% (467/1359)

41.2% (42/102)

39.0% (171/438)

31.0% (254/819)

 

 towards male

65.6% (892 /1359)

58.8% (60/102)

61.0% (267/438)

69.0% (565/819)

 

Had discontinued using in 31.12.21 (n)

107

24

45

38

 

Discontinued hormonal GR (% (n/N)) was

    

0.003*

 towards female

45.8% (49/107)

70.8% (17/24)

44.4% (20/45)

31.6% (12/38)

 

 towards male

54.2% (58/107)

29.2% (7/24)

55.6% (25/45)

68.4% (26/38)

 

Age at index contact, years (mean(sd))

     

 continued hormonal GR

25.3 (9.0)

30.2 (7.8)

25.6 (9.1)

24.6 (9.0)

< 0.001

 discontinued hormonal GR

29.4 (10.7)

34.0 (7.9)

27.2 (10.2)

29.0 (11.9)

0.04

  p

p < 0.001

p = 0.04

p = 0.3

p = 0.03

 

Age at latest purchase of hormones, years (mean(sd)

     

 continued hormonal GR

34.3 (10.5)

50.7 (8.6)

37.7 (9.6)

30.9 (9.0)

< 0.001

 discontinued hormonal GR

37.7 (11.6)

47.9 (7.5)

35.7 (10.4)

33.7 (11.5)

< 0.001

  p

p = 0.001

p = 0.2

p = 0.2

p = 0.07

 

Months on hormonal GR (mean(sd); median)

     

 continued hormonal GR

61.6 (57.0); 44

209.7 (59.3); 207

94.8 (35.2); 95

30.1 (22.1); 27

< 0.001

 discontinued hormonal GR

66.6 (58.0); 48

120.6 (58.6); 128

65.9 (41.8); 57

33.3 (43.6); 16

< 0.001

 p

p = 1.0

p < 0.001

p < 0.001

p = 0.6

 

Specialist level psychiatric treatment contact

     

 continued hormonal GR

56.5% (708/1252)

57.7% (45/78)

63.4% (249/393)

53.0% (414/781)

0.003

 discontinued hormonal GR

67.3% (72/107)

66.7% (16/22)

66.7% (30/45)

68.4% (26/38)

1

  p

p = 0.03

p = 0.5

p = 0.7

p = 0.07

 
  1. *Mantel-Henzel test for linear association