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Geriatric psychiatry and cognitive disorders

Section edited by  Joanne Ryan

This section incorporates all areas of geriatric psychiatry. Topics of interest include, but are not limited to, dementia, biomarkers, pathogenesis, tau pathology and drug development.

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  1. Content type: Research article

    One third of older people are estimated to die with dementia, which is a principal cause of death in developed countries. While it is assumed that people die with severe dementia this is not based on evidence.

    Authors: Jesutofunmi Aworinde, Nomi Werbeloff, Gemma Lewis, Gill Livingston and Andrew Sommerlad

    Citation: BMC Psychiatry 2018 18:355

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  2. Content type: Research article

    Tooth loss is suggested to be associated with an increased risk of dementia in many studies. But the relationship between tooth loss and dementia is not yet fully understood. This systematic review and meta-an...

    Authors: Wen-li Fang, Mu-jun Jiang, Bei-bei Gu, Ying-mei Wei, Sheng-nuo Fan, Wang Liao, Yu-qiu Zheng, Shao-wei Liao, Ying Xiong, Yi Li, Song-hua Xiao and Jun Liu

    Citation: BMC Psychiatry 2018 18:345

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  3. Content type: Research article

    “Behaviour that Challenges” is common in people living with dementia, resident in care homes and historically has been treated with anti-psychotics. However, such usage is associated with 1800 potentially avoi...

    Authors: Ian D Maidment, Sarah Damery, Niyah Campbell, Nichola Seare, Chris Fox, Steve Iliffe, Andrea Hilton, Graeme Brown, Nigel Barnes, Jane Wilcock, Emma Randle, Sarah Gillespie, Garry Barton and Rachel Shaw

    Citation: BMC Psychiatry 2018 18:340

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  4. Content type: Research article

    Depression is an important public health concern due to its devastating morbidity and mortality among older adults. The aim of this study was to assess the prevalence of depression and associated factors among...

    Authors: Yohannes Mirkena, Mebratu Mitiku Reta, Kibrom Haile, Zebiba Nassir and Malede Mequanent Sisay

    Citation: BMC Psychiatry 2018 18:338

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  5. Content type: Research article

    Evaluation of telepsychiatry (via videoconference) for older adults is mostly focussed on nursing homes or inpatients. We evaluated the role of a community based program for older adults in rural and remote re...

    Authors: Pallavi Dham, Neeraj Gupta, Jacob Alexander, Warwick Black, Tarek Rajji and Elaine Skinner

    Citation: BMC Psychiatry 2018 18:316

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  6. Content type: Research article

    The ability to perform activities of daily living (ADLs) is a central marker in the diagnosis and progression of the dementia syndrome. ADLs can be identified as basic ADLs (BADLs), which are fairly easy to pe...

    Authors: Stephanie Book, Katharina Luttenberger, Mark Stemmler, Sebastian Meyer and Elmar Graessel

    Citation: BMC Psychiatry 2018 18:308

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  7. Content type: Research article

    Most persons with dementia die in long term care (LTC) homes, where palliative approaches are appropriate. However, palliative approaches have not been widely implemented and there is limited understanding of ...

    Authors: Lynn McCleary, Genevieve N Thompson, Lorraine Venturato, Abigail Wickson-Griffiths, Paulette Hunter, Tamara Sussman and Sharon Kaasalainen

    Citation: BMC Psychiatry 2018 18:307

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  8. Content type: Research article

    Previous studies have demonstrated that individual measures of fitness – such as reduced pulmonary function, slow walking speed and weak handgrip – are associated with an increased risk of dementia. Only a min...

    Authors: Ruth A. Sibbett, Tom C. Russ, Mike Allerhand, Ian J. Deary and John M. Starr

    Citation: BMC Psychiatry 2018 18:285

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  9. Content type: Research article

    Disrupted serotonergic signaling is often a feature of depression and the role of the serotonin transporter gene (SLC6A4), responsible for serotonin re-uptake, has received much attention in this regard. Most stu...

    Authors: Dilys Lam, Marie-Laure Ancelin, Karen Ritchie, Rosanne Freak-Poli, Richard Saffery and Joanne Ryan

    Citation: BMC Psychiatry 2018 18:282

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  10. Content type: Study protocol

    Scientific research on palliative care in dementia is still underdeveloped. In particular, there are no research studies at all on palliative care issues in young onset dementia (YOD), although significant dif...

    Authors: Janine Diehl-Schmid, Julia Hartmann, Carola Roßmeier, Lina Riedl, Hans Förstl, Silvia Egert-Schwender, Victoria Kehl, Helga Schneider-Schelte and Ralf J. Jox

    Citation: BMC Psychiatry 2018 18:271

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  11. Content type: Research article

    A newer generation neuropsychological tests can take advantage of touch screen and mobile technology. We have developed a new Android application termed “User eXperience-Trail Making Test (UX-TMT)” for neuroco...

    Authors: Naomi Kokubo, Yuma Yokoi, Yuji Saitoh, Miho Murata, Kazushi Maruo, Yoshitake Takebayashi, Issei Shinmei, Sadanobu Yoshimoto and Masaru Horikoshi

    Citation: BMC Psychiatry 2018 18:220

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  12. Content type: Research article

    It is recommended that critically ill patients undergo routine delirium monitoring with a valid and reliable tool such as the Confusion Assessment Method for the Intensive Care Unit (CAM-ICU). However, the val...

    Authors: Maha H. Aljuaid, Ahmad M. Deeb, Maamoun Dbsawy, Daniah Alsayegh, Moteb Alotaibi and Yaseen M. Arabi

    Citation: BMC Psychiatry 2018 18:91

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  13. Content type: Research article

    Rates of psychiatric conditions common to end-stage cancer patients (delirium, depression, anxiety disorders) remain unchanged. However, patient numbers have increased as the population has aged; indeed, cance...

    Authors: Ralph J. Johnson III

    Citation: BMC Psychiatry 2018 18:85

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  14. Content type: Research article

    Demographic aging of society poses numerous challenges, including the provision of health care to the elderly population. According to World Health Organization data, the most frequent mental disorders in the ...

    Authors: Mateusz Cybulski, Lukasz Cybulski, Elzbieta Krajewska-Kulak and Urszula Cwalina

    Citation: BMC Psychiatry 2017 17:383

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  15. Content type: Research article

    Clinical and social services both are important for dementia care. The International Dementia Alliance (IDEAL) Schedule for the Assessment and Staging of Care was developed to guide clinical and social care fo...

    Authors: Xiao Wang, Zhenghai Sun, Lingchuan Xiong, Maya Semrau, Jianhua He, Yang Li, Jianzhong Zhu, Nan Zhang, Aimin Wang, Qinpu Jiang, Nan Mu, Yuping Zhao, Wei Chen, Donghui Wu, Zhanjie Zheng, Yongan Sun…

    Citation: BMC Psychiatry 2017 17:371

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  16. Content type: Research article

    It is estimated that there are about 25,000 people from UK ethnic minority groups with dementia. It is clear that there is an increasing need to improve access to dementia services for all ethnic groups to ens...

    Authors: Cassandra Kenning, Gavin Daker-White, Amy Blakemore, Maria Panagioti and Waquas Waheed

    Citation: BMC Psychiatry 2017 17:316

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  17. Content type: Research article

    This study examined trends in the prescription of benzodiazepines for the elderly (age over 65 years) in Korea, a country with a higher level of spending on pharmaceuticals compared to that in other Organizati...

    Authors: Soo-Hee Hwang, Seungjin Han, Hyojung Choi, Choonseon Park, Sun Min Kim and Tae Hyun Kim

    Citation: BMC Psychiatry 2017 17:303

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  18. Content type: Research article

    The aim of this study was to explore trends in treatment with antipsychotic medication in Swedish dementia care in nursing homes as reported in the most recent empirical studies on the topic, and to relate the...

    Authors: Staffan Karlsson, Ingalill Rahm Hallberg, Patrik Midlöv and Cecilia Fagerström

    Citation: BMC Psychiatry 2017 17:251

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  19. Content type: Research article

    Studies investigating the risk factors for or causation of dementia must consider subjects prior to disease onset. To overcome the limitations of prospective studies and self-reported recall of information, th...

    Authors: Ruth A. Sibbett, Tom C. Russ, Ian J. Deary and John M. Starr

    Citation: BMC Psychiatry 2017 17:239

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  20. Content type: Research article

    With increasing numbers of people surviving beyond eighty years, this section of the population demands attention to reduce the impact of dementia. In order to develop effective preventative strategies, it is ...

    Authors: Ruth A. Sibbett, Tom C. Russ, Ian J. Deary and John M. Starr

    Citation: BMC Psychiatry 2017 17:205

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  21. Content type: Research article

    Psychotropic drug use and alcohol consumption among older adults need to be monitored over time as their use or combined use bears risks of harms. Representative data on changes in prevalence, patterns and co-...

    Authors: Ingrid-Katharina Wolf, Yong Du and Hildtraud Knopf

    Citation: BMC Psychiatry 2017 17:90

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  22. Content type: Research article

    Numerous studies suggesting the relation between self-rated health (SRH) and depression have been reported using different measures. Therefore, we attempted to determine the difference in a depressive scale ba...

    Authors: Jaeyong Shin, Eun-Cheol Park, Sang Gyu Lee, Young Choi, Jae-Hyun Kim and Tae Hyun Kim

    Citation: BMC Psychiatry 2016 16:433

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  23. Content type: Study protocol

    According to the World Alzheimer Report (Prince, The Global Impact of Dementia: an Analysis of Prevalence, Incidence, Cost and Trends, 2015), 46.8 million people worldwide are nowadays living with dementia. An...

    Authors: O. Realdon, F. Rossetto, M. Nalin, I. Baroni, M. Cabinio, R. Fioravanti, F. L. Saibene, M. Alberoni, F. Mantovani, M. Romano, R. Nemni and F. Baglio

    Citation: BMC Psychiatry 2016 16:425

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  24. Content type: Research article

    At present, the exact mechanism of postoperative delirium has not been elucidated. The purpose of this study was to analyze the incidence of delirium in patients undergoing orthopedic surgeries and to explore ...

    Authors: Li-Hong Wang, Dong-Juan Xu, Xian-Jiao Wei, Hao-Teng Chang and Guo-Hong Xu

    Citation: BMC Psychiatry 2016 16:418

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  25. Content type: Research article

    Although various physical risk factors for delirium have been identified, the effect of psychological aspects is currently unknown. This study aimed to examine psychological risk factors for postoperative deli...

    Authors: Jung Eun Shin, Sunghyon Kyeong, Jong-Seok Lee, Jin Young Park, Woo Suk Lee, Jae-Jin Kim and Kyu Hyun Yang

    Citation: BMC Psychiatry 2016 16:371

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  26. Content type: Research article

    While observational studies show that an active lifestyle including cognitive, physical, and social activities is associated with a reduced risk of cognitive decline and dementia, experimental evidence from co...

    Authors: Olivia C. Küster, Patrick Fissler, Daria Laptinskaya, Franka Thurm, Andrea Scharpf, Alexander Woll, Stephan Kolassa, Arthur F. Kramer, Thomas Elbert, Christine A. F. von Arnim and Iris-Tatjana Kolassa

    Citation: BMC Psychiatry 2016 16:315

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  27. Content type: Research article

    Depressive symptoms are prevalent in patients with coronary artery disease (CAD). It is unclear, however, how depressive symptoms change over time and the impact of these changes on long-term functional outcom...

    Authors: M. Elizabeth Wilcox, Elizabeth A. Freiheit, Peter Faris, David B. Hogan, Scott B. Patten, Todd Anderson, William A. Ghali, Merril Knudtson, Andrew Demchuk and Colleen J. Maxwell

    Citation: BMC Psychiatry 2016 16:277

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  28. Content type: Research article

    Patients hospitalized on acute psychogeriatric wards are a heterogeneous population. Cluster analysis is a useful statistical method for partitioning a sample of patients into well separated groups of patients...

    Authors: Claudia Ortoleva Bucher, Nicole Dubuc, Armin von Gunten, Lise Trottier and Diane Morin

    Citation: BMC Psychiatry 2016 16:261

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  29. Content type: Study protocol

    Nearly all persons with dementia will experience neuropsychiatric symptoms (NPS) during the course of their disease. Clinicians and researchers emphasize the need for an evidence-informed standardized approach...

    Authors: Bjørn Lichtwarck, Geir Selbaek, Øyvind Kirkevold, Anne Marie Mork Rokstad, Jūratė Šaltytė Benth, Janne Myhre, Solvor Nybakken and Sverre Bergh

    Citation: BMC Psychiatry 2016 16:233

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  30. Content type: Research article

    Information on validity and reliability of delirium criteria is necessary for clinicians, researchers, and further developments of DSM or ICD. We compare four DSM and ICD delirium diagnostic criteria versions,...

    Authors: Esteban Sepulveda, José G. Franco, Paula T. Trzepacz, Ana M. Gaviria, David J. Meagher, José Palma, Eva Viñuelas, Imma Grau, Elisabet Vilella and Joan de Pablo

    Citation: BMC Psychiatry 2016 16:167

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  31. Content type: Study protocol

    There is an urgent need for psychosocial interventions that effectively support dementia caregivers in daily life. The Experience Sampling Methodology (ESM) offers the possibility to provide a more dynamic vie...

    Authors: Rosalia J. M. van Knippenberg, Marjolein E. de Vugt, Rudolf W. Ponds, Inez Myin-Germeys and Frans R. J. Verhey

    Citation: BMC Psychiatry 2016 16:136

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  32. Content type: Research article

    Depression is a common comorbid psychiatric symptom in patients with Alzheimer’s disease (AD), and the prevalence of depression is higher among people with AD compared with healthy older adults. Comorbid depre...

    Authors: Zhongwei Guo, Jiangtao Zhang, Xiaozheng Liu, Hongtao Hou, Yulin Cao, Fuquan Wei, Japeng Li, Xingli Chen, Yuedi Shen and Wei Chen

    Citation: BMC Psychiatry 2015 15:306

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  33. Content type: Research article

    Brain reserve, i.e., the ability of the brain to tolerate age- and disease-related changes in a way that cognitive function is still maintained, is assumed to be based on the lifelong training of various abili...

    Authors: Simon Forstmeier and Andreas Maercker

    Citation: BMC Psychiatry 2015 15:293

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  34. Content type: Research article

    Lifestyle factors represent prime targets for behaviour change interventions to promote healthy ageing and reduce dementia risk. We evaluated a goal-setting intervention aimed at promoting increased cognitive ...

    Authors: Linda Clare, Sharon M Nelis, Ian R Jones, John V Hindle, Jeanette M Thom, Julie A Nixon, Jennifer Cooney, Carys L Jones, Rhiannon Tudor Edwards and Christopher J Whitaker

    Citation: BMC Psychiatry 2015 15:25

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  35. Content type: Research article

    We aimed to examine the course of depression during 2-year follow-up in a group clinically depressed older persons. Subsequently, we studied which socio-demographic and clinical characteristics predict a depre...

    Authors: Hannie C Comijs, Jasper Nieuwesteeg, Rob Kok, Harm W van Marwijk, Roos C van der Mast, Paul Naarding, Richard C Oude Voshaar, Peter Verhaak, Margot WM de Waal and Max L Stek

    Citation: BMC Psychiatry 2015 15:20

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  36. Content type: Research article

    Many of the assessment tools used to study depression among older people are adaptations of instruments developed in other cultural setting. There is a need to validate those instruments in low and middle inco...

    Authors: Mariella Guerra, Cleusa Ferri, Juan Llibre, A Matthew Prina and Martin Prince

    Citation: BMC Psychiatry 2015 15:12

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  37. Content type: Study protocol

    Alzheimer’s disease and related disorders are characterized by cognitive impairment associated with behavioral and psychological symptoms of dementia. These symptoms have significant consequences for both the ...

    Authors: Elodie Pongan, Magalie Freulon, Floriane Delphin-Combe, Florence Dibie-Racoupeau, Géraldine Martin-Gaujard, Denis Federico, Aziza Waissi, Gaëlle Richard, Sophie Jacqueline, Florence Fabre, Béatrice Trombert-Paviot, Pierre Krolak-Salmon, Bernard Laurent and Isabelle Rouch

    Citation: BMC Psychiatry 2014 14:308

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  38. Content type: Research article

    APOE is the biomarker with the greatest known influence on cognitive function; however, the effect of complex haplotypes involving polymorphisms rs449647, rs405509, rs440446, rs429358 and rs7412 has never been s...

    Authors: Diddier Prada, Elena Colicino, Melinda C Power, David G Cox, Marc G Weisskopf, Lifang Hou, Avron Spiro III, Pantel Vokonas, Jia Zhong, Marco Sanchez-Guerra, Luis A Herrera, Joel Schwartz and Andrea A Baccarelli

    Citation: BMC Psychiatry 2014 14:223

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  39. Content type: Study protocol

    The Whitehall II (WHII) study of British civil servants provides a unique source of longitudinal data to investigate key factors hypothesized to affect brain health and cognitive ageing. This paper introduces ...

    Authors: Nicola Filippini, Enikő Zsoldos, Rita Haapakoski, Claire E Sexton, Abda Mahmood, Charlotte L Allan, Anya Topiwala, Vyara Valkanova, Eric J Brunner, Martin J Shipley, Edward Auerbach, Steen Moeller, Kâmil Uğurbil, Junqian Xu, Essa Yacoub, Jesper Andersson…

    Citation: BMC Psychiatry 2014 14:159

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  40. Content type: Research article

    Getting lost outside is stressful for people with dementia and their caregivers and a leading cause of long-term institutionalisation. Although Global Positional Satellite (GPS) location has been promoted to f...

    Authors: Heather Milne, Marjon van der Pol, Lucy McCloughan, Janet Hanley, Gillian Mead, John Starr, Aziz Sheikh and Brian McKinstry

    Citation: BMC Psychiatry 2014 14:160

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  41. Content type: Research article

    Dementia affects 35 million people worldwide and is currently incurable. Many cases may be preventable because regular participation in physical, mental and social leisure activities during middle age is assoc...

    Authors: Thomas M Dannhauser, Martin Cleverley, Tim J Whitfield, Ben (C) Fletcher, Tim Stevens and Zuzana Walker

    Citation: BMC Psychiatry 2014 14:129

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  42. Content type: Research article

    The epidemiologic study of comorbidities of an index health problem represents a methodological challenge. This study cross-sectionally describes and analyzes the comorbidities associated with dementia in olde...

    Authors: Beatriz Poblador-Plou, Amaia Calderón-Larrañaga, Javier Marta-Moreno, Jorge Hancco-Saavedra, Antoni Sicras-Mainar, Michael Soljak and Alexandra Prados-Torres

    Citation: BMC Psychiatry 2014 14:84

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  43. Content type: Research article

    The relation between sense of coherence (SOC) and quality of life (QoL) among older persons has been found in some, but not all, studies and mostly in studies with cross-sectional design. We wanted to study if...

    Authors: Anne-Sofie Helvik, Knut Engedal and Geir Selbæk

    Citation: BMC Psychiatry 2014 14:82

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  44. Content type: Research article

    In psychiatry, most of the focus on patient aggression has been in adolescent and adult inpatient settings. This behaviour is also common in elderly people with mental illness, but little research has been con...

    Authors: Terence V McCann, John Baird and Eimear Muir-Cochrane

    Citation: BMC Psychiatry 2014 14:80

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  45. Content type: Research article

    Decline in verbal episodic memory is a core feature of amnestic mild cognitive impairment (aMCI). The delayed story recall (DSR) test from the Adult Memory and Information Processing Battery (AMIPB) discrimina...

    Authors: Jing Shi, Mingqing Wei, Jinzhou Tian, Julie Snowden, Xuekai Zhang, Jingnian Ni, Ting Li, Wenjia Jian, Congcong Ma, Yanping Tong, Jianping Liu, Tonghua Liu, Pengwen Wang and Yongyan Wang

    Citation: BMC Psychiatry 2014 14:71

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  46. Content type: Research article

    Performance on psychometric tests is key to diagnosis and monitoring treatment of dementia. Results are often reported as a total score, but there is additional information in individual items of tests which v...

    Authors: Sarah McGrory, Jason M Doherty, Elizabeth J Austin, John M Starr and Susan D Shenkin

    Citation: BMC Psychiatry 2014 14:47

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  47. Content type: Research article

    Due to fragmented mental, somatic, and social healthcare services, it can be hard to engage into care older patients with severe mental illness (SMI). In adult mental health care, assertive community treatment...

    Authors: Jolanda Stobbe, André I Wierdsma, Rob M Kok, Hans Kroon, Bert-Jan Roosenschoon, Marja Depla and Cornelis L Mulder

    Citation: BMC Psychiatry 2014 14:42

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