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Mood disorders

Section edited by Florian Seemüller

This section is dedicated to covering all aspects of a wide range of mood disorders. Topics of interest include, but are not limited to, biological psychiatry, depression, psychoneuroendocrinology, bipolar disorders, antidepressants, psychopharmacology, neuroimaging, transcranial/cortical stimulation, electroencephalography and co-morbid conditions associated with mood disorders.


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  1. This forms the first study of a group-based psychoeducation program for inpatients following remission of a manic episode in patients suffering from bipolar I disorder in a Chinese population. The aim was to e...

    Authors: Runsen Chen, Yingjun Xi, Xue Wang, Yaqiong Li, Yuyang He and Jiong Luo

    Citation: BMC Psychiatry 2018 18:26

    Content type: Research article

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  2. Experience sampling, a method for real-time self-monitoring of affective experiences, holds opportunities for person-tailored treatment. By focussing on dynamic patterns of positive affect, experience sampling...

    Authors: Claudia J. P. Simons, Marjan Drukker, Silvia Evers, Ghislaine A. P. G. van Mastrigt, Petra Höhn, Ingrid Kramer, Frenk Peeters, Philippe Delespaul, Claudia Menne-Lothmann, Jessica A. Hartmann, Jim van Os and Marieke Wichers

    Citation: BMC Psychiatry 2017 17:415

    Content type: Research article

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  3. A number of epidemiological studies have examined the effect of meat consumption on depression. However, no conclusion has been reached. The aim of this study was to examine the relationship between meat consu...

    Authors: Yi Zhang, Ye Yang, Ming-sheng Xie, Xiang Ding, Hui Li, Zhi-chen Liu and Shi-fang Peng

    Citation: BMC Psychiatry 2017 17:409

    Content type: Research article

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  4. Few actigraphy studies in mood disorders have simultaneously included unipolar (UP) and bipolar (BD) depression or BD mixed states as a separate subgroup from mania. This study compared objectively measured ac...

    Authors: Karoline Krane-Gartiser, Arne E. Vaaler, Ole Bernt Fasmer, Kjetil Sørensen, Gunnar Morken and Jan Scott

    Citation: BMC Psychiatry 2017 17:404

    Content type: Research article

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  5. Patients with chronic depression (persisting symptoms for ≥2 years) are a clinically relevant group with extensive (co)morbidity, high functional impairment and associated costs in primary care. The General Pr...

    Authors: Florian Wolf, Antje Freytag, Sven Schulz, Thomas Lehmann, Susann Schaffer, Horst Christian Vollmar, Thomas Kühlein and Jochen Gensichen

    Citation: BMC Psychiatry 2017 17:401

    Content type: Research article

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  6. Guidance of patients treated with antidepressants is paramount for successful therapy. The aim was to assess patients’ needs and suggestions for improvement of guidance by physicians and pharmacists during sec...

    Authors: Mariёtte Nederlof, Daniёlle C. Cath, Lennart J. Stoker, Toine C. G. Egberts and Eibert R. Heerdink

    Citation: BMC Psychiatry 2017 17:388

    Content type: Research article

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  7. Depression is one of the most common diagnosed psychiatric disorders in the world. Besides individual risk factors, it is also found that environment and socio-cultural factors are the other main risk factors ...

    Authors: Mehmet Çakıcı, Özlem Gökçe, Asra Babayiğit, Ebru Çakıcı and Ayhan Eş

    Citation: BMC Psychiatry 2017 17:387

    Content type: Research article

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  8. The manifestation of major depressive disorder (MDD) may include cognitive symptoms that can precede the onset of MDD and persist beyond the resolution of acute depressive episodes. However, little is known ab...

    Authors: Bjarke Ebert, Kamilla Miskowiak, Morten Kloster, Jon Johansen, Cara Eckholm, Torbjörn Wærner, Mads Holme and Louise Meldgaard Bruun

    Citation: BMC Psychiatry 2017 17:370

    Content type: Research article

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  9. Despite the availability of evidence based treatments, many people with major depression receive no or delayed professional treatment, which may put them at risk for adverse outcomes. The aim of this study was...

    Authors: A. M. Boerema, M. ten Have, A. Kleiboer, R. de Graaf, J. Nuyen, P. Cuijpers and A. T. F. Beekman

    Citation: BMC Psychiatry 2017 17:367

    Content type: Research article

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  10. Highly hypnotizable individuals have impaired executive function, elevated motor impulsivity and increased emotional sensitivity, which are sometimes found in bipolar disorder patients. It is then reasonable t...

    Authors: Bingren Zhang, Jiawei Wang, Qisha Zhu, Guorong Ma, Chanchan Shen, Hongying Fan and Wei Wang

    Citation: BMC Psychiatry 2017 17:362

    Content type: Research article

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  11. In clinical practice, some patients diagnosed with anxiety disorder (AD) may develop bipolar disorder (BD) many years later, and some cases of AD may be cured by the use of mood stabilizers. However, the relat...

    Authors: Na Du, Ya-ling Zhou, Xu Zhang, Jing Guo and Xue-li Sun

    Citation: BMC Psychiatry 2017 17:351

    Content type: Research article

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  12. In Western European countries, the prevalence of depressive symptoms is higher among ethnic minority groups, compared to the host population. We explored whether these inequalities reflect variance in the way ...

    Authors: Henrike Galenkamp, Karien Stronks, Marieke B. Snijder and Eske M. Derks

    Citation: BMC Psychiatry 2017 17:349

    Content type: Research article

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  13. Increased prevalence of depression is found in both type 2 diabetes (T2D) and type 1 diabetes (T1D). Melancholia and atypical depression differ by cortisol secretion and clinical features. The aim was to compa...

    Authors: Eva O. Melin, Maria Thunander, Mona Landin-Olsson, Magnus Hillman and Hans O. Thulesius

    Citation: BMC Psychiatry 2017 17:335

    Content type: Research article

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  14. The prevalence of depressive symptoms in hypothyroidism is high. Considering that hypothyroidism and depression share some clinical features, some researchers use the “brain hypothyroidism” hypothesis to expla...

    Authors: A Talaei, N Rafee, F Rafei and A Chehrei

    Citation: BMC Psychiatry 2017 17:327

    Content type: Research article

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  15. There is a physical inactivity pandemic around the world despite the known benefits of engaging in physical activity. This is true for individuals who would receive notable benefits from physical activity, in ...

    Authors: Joanie Sims-Gould, Sara Vazirian, Neville Li, Ronald Remick and Karim Khan

    Citation: BMC Psychiatry 2017 17:319

    Content type: Research article

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  16. Anxiety and depression are associated with a range of adverse outcomes and represent a large global burden to individuals and health care systems. Prevention programs are an important way to avert a proportion...

    Authors: M. Deady, I. Choi, R. A. Calvo, N. Glozier, H. Christensen and S. B. Harvey

    Citation: BMC Psychiatry 2017 17:310

    Content type: Research article

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  17. The aim of this study was to explore the relationships between depressive symptoms and health-related quality of life (HRQOL) measurements for inpatients with major depressive disorder (MDD) before and after 6...

    Authors: Wei-Cheng Yang, Ching-Hua Lin, Fu-Chiang Wang and Mei-Jou Lu

    Citation: BMC Psychiatry 2017 17:309

    Content type: Research article

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  18. Psychotherapy is successful for the majority of patients, but not for every patient. Hence, further knowledge is needed on how treatments should be adapted for those who do not profit or deteriorate. In the la...

    Authors: Wolfgang Lutz, Dirk Zimmermann, Viola N. L. S. Müller, Anne-Katharina Deisenhofer and Julian A. Rubel

    Citation: BMC Psychiatry 2017 17:306

    Content type: Study protocol

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  19. Antenatal depressive symptoms affect around 12.3% of women in in low and middle income countries (LMICs) and data are accumulating about associations with adverse outcomes for mother and child. Studies from ru...

    Authors: Tesera Bitew, Charlotte Hanlon, Eskinder Kebede, Simone Honikman and Abebaw Fekadu

    Citation: BMC Psychiatry 2017 17:301

    Content type: Research article

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  20. Men who have sex with men (MSM) continue to be at an increased risk of Violence, HIV transmission and Mental Disorders such as depression on top of many other bio-psycho-socio challenges they face as a result ...

    Authors: Lucy R. Mgopa, Jessie Mbwambo, Samuel Likindikoki and Pedro Pallangyo

    Citation: BMC Psychiatry 2017 17:296

    Content type: Research article

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  21. The prevalence of major depressive disorder (MDD) in Spanish primary care (PC) centres is high. However, MDD is frequently underdiagnosed and consequently only some patients receive the appropriate treatment. ...

    Authors: Roger Muñoz-Navarro, Antonio Cano-Vindel, Leonardo Adrián Medrano, Florian Schmitz, Paloma Ruiz-Rodríguez, Carmen Abellán-Maeso, Maria Antonia Font-Payeras and Ana María Hermosilla-Pasamar

    Citation: BMC Psychiatry 2017 17:291

    Content type: Research article

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  22. The distributional pattern of total scores on depression screening scales in the general population has not been well studied. Recent studies suggest that the total scores on depression screening scales follow...

    Authors: Shinichiro Tomitaka, Yohei Kawasaki, Kazuki Ide, Maiko Akutagawa, Hiroshi Yamada, Yutaka Ono and Toshiaki A. Furukawa

    Citation: BMC Psychiatry 2017 17:290

    Content type: Research article

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  23. Depression is projected to be the primary cause of disability worldwide by 2030. In a recent survey, the most commonly cited unmet need among 42.4% of depressed Albertans was the lack of sufficient, accessible...

    Authors: Vincent I. O. Agyapong, Michal Juhás, Arto Ohinmaa, Joy Omeje, Kelly Mrklas, Victoria Y. M. Suen, Serdar M. Dursun and Andrew J. Greenshaw

    Citation: BMC Psychiatry 2017 17:286

    Content type: Research article

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  24. There remains a paucity of research on control attribution and depression within Asian populations. This study examines: (1) Success/Failure condition as a moderator between depression and negative affect or s...

    Authors: Si-Ning Yeo, Hani Zainal, Catherine S. Tang, Eddie M. Tong, Cyrus S. Ho and Roger C. Ho

    Citation: BMC Psychiatry 2017 17:285

    Content type: Research article

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  25. Previous studies have examined associations between sitting time and negative health outcomes and mental health. However, the relationship between overall sitting time and major depressive disorder (MDD) in So...

    Authors: Jin Young Nam, Juyeong Kim, Kyoung Hee Cho, Jaewoo Choi, Jaeyong Shin and Eun-Cheol Park

    Citation: BMC Psychiatry 2017 17:274

    Content type: Research article

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  26. Interactions between the digestive system, brain functions and immunoglobulin G (IgG) mediated immunity against food antigens became recently a topic of growing interest in psychiatry research. Psychological s...

    Authors: Leszek Rudzki, Dariusz Pawlak, Krystyna Pawlak, Napoleon Waszkiewicz, Aleksandra Małus, Beata Konarzewska, Mirosława Gałęcka, Anna Bartnicka, Lucyna Ostrowska and Agata Szulc

    Citation: BMC Psychiatry 2017 17:268

    Content type: Research article

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  27. Acculturation is a long-term, multi-dimensional process occurring when subjects of different cultures stay in continuous contact. Previous studies have suggested that elevated rates of depression among differe...

    Authors: Hanna Janssen-Kallenberg, Holger Schulz, Ulrike Kluge, Jens Strehle, Hans-Ulrich Wittchen, Uwe Wolfradt, Uwe Koch-Gromus, Andreas Heinz, Mike Mösko and Demet Dingoyan

    Citation: BMC Psychiatry 2017 17:264

    Content type: Research article

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  28. Despite the availability of evidence-based treatments for depression, a large proportion of patients remains untreated or adequate treatment is initiated with delay. This situation is particularly critical in ...

    Authors: Birgit Watzke, Elisa Haller, Maya Steinmann, Daniela Heddaeus, Martin Härter, Hans-Helmut König, Karl Wegscheider and Thomas Rosemann

    Citation: BMC Psychiatry 2017 17:263

    Content type: Study protocol

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  29. Seasonal affective disorder (SAD) is a seasonally recurrent type of major depression. This predictable aspect makes it promising for preventive treatment. However, evidence for the efficacy and harm of prevent...

    Authors: B. Nussbaumer-Streit, D. Winkler, M. Spies, S. Kasper and E. Pjrek

    Citation: BMC Psychiatry 2017 17:247

    Content type: Research article

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  30. Prevalence rates of minor and major depression vary from 0.7 to 6.8 (minor) and 3.8 to 10.9 (major) for the general population. Twenty-two percent of older, long-term unemployed people suffer from major depres...

    Authors: Sabrina Pfeil, Katrin Holtz, Kathrin-Andrea Kopf, Ulrich Hegerl and Christine Rummel-Kluge

    Citation: BMC Psychiatry 2017 17:243

    Content type: Research article

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  31. Several studies have indicated that obsessive-compulsive disorder (OCD) is a common comorbidity in patients with psychotic disorders, but there is sparse knowledge about the relationship between symptoms of OC...

    Authors: Kristen Hagen, Stian Solem, Håvard Berg Opstad, Bjarne Hansen and Roger Hagen

    Citation: BMC Psychiatry 2017 17:233

    Content type: Research article

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  32. Approximately 30–50% of patients with major depressive disorder can be classed as treatment resistant, widely defined as a failure to respond to two or more adequate trials of antidepressants in the current ep...

    Authors: L. Marwood, R. Taylor, K. Goldsmith, R. Romeo, R. Holland, A. Pickles, J. Hutchinson, D. Dietch, A. Cipriani, R. Nair, M.-J. Attenburrow, A. H. Young, J. Geddes, R. H. McAllister-Williams and A. J. Cleare

    Citation: BMC Psychiatry 2017 17:231

    Content type: Study protocol

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  33. Depressive symptoms are common in older adults. The effectiveness of pharmacological treatments and the availability of psychological treatments in primary care are limited. A behavioural approach to depressio...

    Authors: Noortje Janssen, Marcus J.H. Huibers, Peter Lucassen, Richard Oude Voshaar, Harm van Marwijk, Judith Bosmans, Mirjam Pijnappels, Jan Spijker and Gert-Jan Hendriks

    Citation: BMC Psychiatry 2017 17:230

    Content type: Study protocol

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  34. Bipolar disorder types I (BD I) and II (BD II) might present different dysfunctions of the cortex and brainstem, as reflected by the second exteroceptive suppression period of temporalis muscle activity (ES2) ...

    Authors: Qisha Zhu, Jiawei Wang, Chanchan Shen, Hongying Fan, Bingren Zhang, Guorong Ma, Yanxia Lu and Wei Wang

    Citation: BMC Psychiatry 2017 17:224

    Content type: Research article

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  35. Although the symptoms of major depressive disorder (MDD) are often manageable with pharmacotherapy, response to first-line antidepressant treatment is often less than optimal. This study describes long-term tr...

    Authors: Geneviève Gauthier, Annie Guérin, Maryia Zhdanava, William Jacobson, George Nomikos, Elizabeth Merikle, Clément François and Vanessa Perez

    Citation: BMC Psychiatry 2017 17:222

    Content type: Research article

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  36. The majority of patients with depressive disorders are treated by general practitioners (GPs) and are prescribed antidepressant medication. Patients prefer psychological treatments but they are under-used, mai...

    Authors: Btissame Massoudi, Marco H. Blanker, Evelien van Valen, Hans Wouters, Claudi L. H. Bockting and Huibert Burger

    Citation: BMC Psychiatry 2017 17:218

    Content type: Study protocol

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  37. Depression is an important contributor to the global burden disease that affects people of communities all over the world. With high level of demands in academics and psychosocial pressure, medical students du...

    Authors: Stewart Ndutard Ngasa, Carlson-Babila Sama, Bonaventure Suiru Dzekem, Kilton Neba Nforchu, Maxime Tindong, Desmond Aroke and Christian Akem Dimala

    Citation: BMC Psychiatry 2017 17:216

    Content type: Research article

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  38. Cognitive Behaviour Therapy (CBT) is the front-line psychological intervention for step 3 within UK psychological therapy services. Counselling is recommended only when other interventions have failed and its ...

    Authors: Jo Pybis, David Saxon, Andy Hill and Michael Barkham

    Citation: BMC Psychiatry 2017 17:215

    Content type: Research article

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  39. Evidence suggests that alcohol use and smoking are negatively associated with mood in bipolar disorders (BD). It is unknown if this relationship is moderated by the number of previous mood episodes. Therefore,...

    Authors: Wendela G. ter Meulen, Jan van Zaane, Stasja Draisma, Aartjan T.F. Beekman and Ralph W. Kupka

    Citation: BMC Psychiatry 2017 17:185

    Content type: Research article

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  40. Blood homocysteine concentration (BHC) is higher in patients with alcohol use disorder (AUD). Previous studies have found a relationship between depressive symptoms severity and BHC in AUD patients and recentl...

    Authors: Francesco Oliva, Maurizio Coppola, Raffaella Mondola, Daniele Ascheri, Francesco Cuniberti, Gabriele Nibbio and Rocco Luigi Picci

    Citation: BMC Psychiatry 2017 17:181

    Content type: Research article

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  41. The primary aim was to examine possible differences in telomere length between primary health care patients, with depression, anxiety or stress and adjustment disorders, and healthy controls. The second aim wa...

    Authors: Xiao Wang, Kristina Sundquist, Anna Hedelius, Karolina Palmér, Ashfaque A. Memon and Jan Sundquist

    Citation: BMC Psychiatry 2017 17:148

    Content type: Research article

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  42. Emotional disorders (ED) are among the most prevalent mental disorders. However, less than 50% of people suffering from ED receive the appropriate treatment. This situation has led to the development of new in...

    Authors: Amanda Díaz-García, Alberto González-Robles, Javier Fernández-Álvarez, Azucena García-Palacios, Rosa María Baños and Cristina Botella

    Citation: BMC Psychiatry 2017 17:145

    Content type: Study protocol

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  43. During the last decade online interventions have emerged as a promising approach for patients with mild/moderate depressive symptoms, reaching at large populations and representing cost-effective alternatives....

    Authors: Azucena Justicia, Matilde Elices, Ana Isabel Cebria, Diego J. Palao, Jesús Gorosabel, Dolors Puigdemont, Javier de Diego-Adeliño, Andrea Gabilondo, Alvaro Iruin, Ulrich Hegerl and Víctor Pérez

    Citation: BMC Psychiatry 2017 17:143

    Content type: Study protocol

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  44. The 2013–2016 West African Ebola outbreak infected 28,616 people and caused 11,310 deaths by 11 May 2016, across six countries. The outbreak has also resulted in the largest number of EVD survivors in history—...

    Authors: Mamady Mory Keita, Bernard Taverne, Sékou Sy Savané, Laura March, Morifodé Doukoure, Mamadou Saliou Sow, Abdoulaye Touré, Jean François Etard, Moumié Barry and Eric Delaporte

    Citation: BMC Psychiatry 2017 17:127

    Content type: Research article

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  45. The course of depression is poorer in clinical settings than in the general population. Several predictors have been studied and there is growing evidence that a history of childhood maltreatment consistently ...

    Authors: Sabrina Paterniti, Irit Sterner, Christine Caldwell and Jean-Claude Bisserbe

    Citation: BMC Psychiatry 2017 17:113

    Content type: Research article

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