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Psychotic disorders

This section focuses on psychotic disorders. Topics of interest include, but are not limited to, schizophrenia, antipsychotics, biochemistry, hallucinations, delusions, neurocognitive functioning and brain imaging.

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  1. In sub-Saharan Africa, common mental disorders (CMDs) like depression and anxiety are under-investigated amongst young people living with HIV (YLWH). To address the gap, in Kenya we: a) determined the prevalen...

    Authors: Moses K. Nyongesa, Paul Mwangi, Michael Kinuthia, Amin S. Hassan, Hans M. Koot, Pim Cuijpers, Charles R. J. C. Newton and Amina Abubakar

    Citation: BMC Psychiatry 2021 21:90

    Content type: Research article

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  2. Neutropenia, a decrease in total number of neutrophils below 1500/mm3 and particularly severe neutropenia, defined as neutrophils less than 500/mm3, is a potential adverse effect of antipsychotic medications that...

    Authors: Natalie Martos, William Hall, Alicia Marhefka, Thomas W. Sedlak and Frederick C. Nucifora Jr

    Citation: BMC Psychiatry 2021 21:76

    Content type: Case report

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  3. Seasonal migrant farmworkers in Ethiopia are a vulnerable segment of the population facing numerous threats to their mental health. This research aimed to determine the magnitude of common mental disorders (CM...

    Authors: Kassahun Alemu Gelaye, Malede Mequanent Sisay, Temesgen Yihunie Akalu, Destaw Fetene Teshome, Haileab Fekadu Wolde, Getu Debalkie Demissie, Sintayehu Daba Wami, Telake Azale and Tadesse Awoke Ayele

    Citation: BMC Psychiatry 2021 21:69

    Content type: Research article

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  4. We aimed to investigate whether females with psychosexual disorders were associated with the risk of affective and other psychiatric disorders. A total of 2240 enrolled individuals, with 560 patients with psyc...

    Authors: Iau-Jin Lin, Nian-Sheng Tzeng, Chi-Hsiang Chung and Wu-Chien Chien

    Citation: BMC Psychiatry 2021 21:63

    Content type: Research article

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  5. Patients with mental illness report lower quality of life (QoL) compared to the general population. Prior research has found several differences in clinical features and experiences of male and female patients...

    Authors: Saleha Shafie, Ellaisha Samari, Anitha Jeyagurunathan, Edimansyah Abdin, Sherilyn Chang, Siow Ann Chong and Mythily Subramaniam

    Citation: BMC Psychiatry 2021 21:61

    Content type: Research article

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  6. Video gaming is a promising intervention for cognitive and social impairment in patients with schizophrenia. A number of gaming interventions have been evaluated in small-scale studies with various patient gro...

    Authors: Maritta Välimäki, Min Yang, Yuen Ting Joyce Lam, Tella Lantta, Matias Palva, Satu Palva, Benjamin Yee, Siu Hung Yip, Kin-sun Dan Yu, Hing Chiu Charles Chang, Po Yee Ivy Cheng and Daniel Bressington

    Citation: BMC Psychiatry 2021 21:46

    Content type: Study protocol

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  7. Fluid intelligence deficits affect executive functioning and social behaviors in patients with schizophrenia. To help clinicians manage fluid intelligence deficits, a psychometrically sound measure is needed. ...

    Authors: Kuan-Wei Chen, Ya-Chen Lee, Tzu-Ying Yu, Li-Jung Cheng, Chien-Yu Chao and Ching-Lin Hsieh

    Citation: BMC Psychiatry 2021 21:39

    Content type: Research article

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  8. Poor adherence and negative attitudes to treatment are common clinical problems when treating psychotic disorders. This study investigated how schizophrenia core symptoms and daily functioning affect treatment...

    Authors: J. Leijala, O. Kampman, J. Suvisaari and S. Eskelinen

    Citation: BMC Psychiatry 2021 21:37

    Content type: Research article

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  9. High rates of psychotropic medications are prescribed in aged care homes despite their limited effectiveness and associated adverse effects. We aim to evaluate the changes in prescription patterns for elderly ...

    Authors: Daya Ram Parajuli, Abraham Kuot, Mohammad Hamiduzzaman, Justin Gladman and Vivian Isaac

    Citation: BMC Psychiatry 2021 21:36

    Content type: Research article

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  10. Schizophrenia is associated with widespread cognitive impairment. The MATRICS Consensus Cognitive Battery (MCCB) is most frequently used to assess cognitive function. However, the MCCB test is time consuming f...

    Authors: Bochao Huang, Shangda Li, Bing Sun, Hailong lyu, Weijuan Xu, Jianping Jiao, Fen Pan, Jianbo Hu, Jinkai Chen, Yaping Chen, Manli Huang and Yi Xu

    Citation: BMC Psychiatry 2021 21:21

    Content type: Research article

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  11. Antipsychotic-induced Weight Gain (AiWG) is a debilitating and common adverse effect of antipsychotics. AiWG negatively impacts life expectancy, quality of life, treatment adherence, likelihood of developing t...

    Authors: Nini de Boer, Sinan Guloksuz, Caroline van Baal, Leonie Willebrands, Jeroen Deenik, Christiaan H. Vinkers, Inge Winter-van Rossum, Janneke Zinkstok, Ingeborg Wilting, Jasper B. Zantvoord, Frank Backx, Wilma E. Swildens, Marieke Schouw, Jan Bogers, Folkwin Hulshof, Rudolf de Knijff…

    Citation: BMC Psychiatry 2021 21:4

    Content type: Study protocol

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  12. The time between discharge from hospital and transition to community and home is a critical period for health status among patients with a mental illness, including patients with schizophrenia. This study aime...

    Authors: Anantree Smithnaraseth, Acharaporn Seeherunwong, Rungnapa Panitrat and Mathuros Tipayamongkholgul

    Citation: BMC Psychiatry 2020 20:592

    Content type: Research article

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  13. Electroencephalography (EEG) frontal alpha asymmetry (FAA) has been observed in several psychiatric disorders. Dominance in left or right frontal alpha activity remains inconsistent in patients with major depr...

    Authors: Kuk-In Jang, Chany Lee, Sangmin Lee, Seung Huh and Jeong-Ho Chae

    Citation: BMC Psychiatry 2020 20:586

    Content type: Research article

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  14. Clozapine is an atypical antipsychotic proven to be superior in the treatment of treatment-resistant schizophrenia. Myocarditis is a rare, but well-known complication of treatment with clozapine. Only few case...

    Authors: M. Z. van der Horst, F. van Houwelingen and J. J. Luykx

    Citation: BMC Psychiatry 2020 20:568

    Content type: Case report

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  15. Autoenucleation is a rare form of self-mutilation typically associated with psychiatric disorders such as schizophrenia, substance-induced psychosis and bipolar disorder. The act is usually unilateral, althoug...

    Authors: Natalia Chechko, Eva Stormanns, Klaus Podoll, Susanne Stickel and Irene Neuner

    Citation: BMC Psychiatry 2020 20:563

    Content type: Case report

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  16. The jumping to conclusions bias (JTC) is considered to be an important causal factor in theoretical models for the formation and maintenance of delusions. However, recent meta-analytic findings show a rather e...

    Authors: Nico Pytlik, Daniel Soll, Klaus Hesse, Steffen Moritz, Andreas Bechdolf, Jutta Herrlich, Tilo Kircher, Stefan Klingberg, Martin W. Landsberg, Bernhard W. Müller, Georg Wiedemann, Andreas Wittorf, Wolfgang Wölwer, Michael Wagner and Stephanie Mehl

    Citation: BMC Psychiatry 2020 20:554

    Content type: Research article

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  17. Switching to aripiprazole from other antipsychotics can avoid antipsychotic-induced hyperprolactinemia but may result in an abnormally low prolactin level. This study aimed to assess whether the aripiprazole-i...

    Authors: Ya-Wen Jen, Tzung-Jeng Hwang, Hung-Yu Chan, Ming H. Hsieh, Chen-Chung Liu, Chih-Min Liu, Hai-Gwo Hwu, Ching-Hua Kuo, Yi-Ting Lin, Yi-Ling Chien and Wei J. Chen

    Citation: BMC Psychiatry 2020 20:552

    Content type: Research article

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  18. Over the past decade, antidepressant prescriptions have increased in European countries and the United States, partly due to an increase in the number of new cases of mental illness. This paper demonstrates an...

    Authors: Mark Cherrie, Sarah Curtis, Gergő Baranyi, Stuart McTaggart, Niall Cunningham, Kirsty Licence, Chris Dibben, Clare Bambra and Jamie Pearce

    Citation: BMC Psychiatry 2020 20:551

    Content type: Research article

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  20. Anhedonia is a core clinical symptom of mental disorders. The Revised Physical Anhedonia Scale (RPAS) and the Revised Social Anhedonia Scale (RSAS) have been applied in clinical and non-clinical samples since ...

    Authors: Qiongqiong Wu, Jiayue He, Shulin Fang, Panwen Zhang, Xingwei Luo, Jianghua Zhang, Yan Xiong, Fusheng Luo, Xiaosheng Wang, Shuqiao Yao and Xiang Wang

    Citation: BMC Psychiatry 2020 20:529

    Content type: Research article

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  21. Antipsychotic medications are the first-line pharmacological intervention for severe mental illnesses (SMI) such as schizophrenia and other psychoses, while also being used to relieve distress and treat neurop...

    Authors: A. H. Heald, M. Stedman, S. Farman, C. Khine, M. Davies, M. De Hert and D. Taylor

    Citation: BMC Psychiatry 2020 20:528

    Content type: Research article

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  22. Reluctance on the part of mental health professionals constitutes an important barrier to patient participation in care. In order to stimulate person-centeredness in the inpatient care of persons with psychoti...

    Authors: Katarina Allerby, Anneli Goulding, Lilas Ali and Margda Waern

    Citation: BMC Psychiatry 2020 20:523

    Content type: Research article

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  23. Personal recovery is associated with many significant health-related factors, but studies exploring associations between activity factors and personal recovery among service users are scarce. The aims of this ...

    Authors: Elisabeth Argentzell, Martin Bäckström, Kristine Lund and Mona Eklund

    Citation: BMC Psychiatry 2020 20:520

    Content type: Research article

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  24. Erotomania, also known as “de Clérambault’s Syndrome”, is a psychiatric syndrome characterized by the delusional belief that one is loved by another person of, generally of a higher social status. Erotomania h...

    Authors: Maria Teresa Tavares Rodrigues Tomaz Valadas and Lucilia Eduarda Abrantes Bravo

    Citation: BMC Psychiatry 2020 20:516

    Content type: Case report

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  25. Psychiatric disorders and ocular neurovascular diseases may share a similar pathophysiological route of vascular structures or neurological changes. The aim of this study is to investigate the association betw...

    Authors: Chun-Hao Liu, Eugene Yu-Chuan Kang, Yu-Hsiang Lin, Wei-Chi Wu, Zhuo-Hao Liu, Chang-Fu Kuo, Chi-Chun Lai and Yih-Shiou Hwang

    Citation: BMC Psychiatry 2020 20:486

    Content type: Research article

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  26. Motivational negative symptoms hinder quality of life and daily functioning of individuals with schizophrenia spectrum disorders. A recently developed intervention, Switch, has shown promising effects on negat...

    Authors: Bénédicte Thonon, Evelyne Van Aubel, Ginette Lafit, Clara Della Libera and Frank Larøi

    Citation: BMC Psychiatry 2020 20:464

    Content type: Research article

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  27. Family and friends of a person developing a mental illness or in a mental health crisis can help the person until treatment is received or the crisis resolves. Guidelines for providing this ‘mental health firs...

    Authors: Wenjing Li, Anthony F. Jorm, Yan Wang, Shurong Lu, Yanling He and Nicola Reavley

    Citation: BMC Psychiatry 2020 20:443

    Content type: Research article

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  28. Exercise may improve cardiorespiratory fitness in people with schizophrenia, however, possible condition-specific cardiorespiratory disadvantages, a scarcity of methodologically sound studies, and conflicting ...

    Authors: Eivind Andersen, Gry Bang-Kittilsen, Therese Torgersen Bigseth, Jens Egeland, Tom Langerud Holmen, Egil Wilhelm Martinsen, Trine Stensrud and John Abel Engh

    Citation: BMC Psychiatry 2020 20:425

    Content type: Research article

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  29. Family interventions in schizophrenia are evidence based and have been adapted to different cultural settings to improve their effectiveness and acceptability. The Arab world has a unique set of socio-cultural...

    Authors: Aziza Al-Sawafi, Karina Lovell, Laoise Renwick and Nusrat Husain

    Citation: BMC Psychiatry 2020 20:413

    Content type: Research article

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  30. Schizophrenia patients with a metabolically abnormal obese (MAO) phenotype have been shown poor cardiovascular outcomes, but the characteristics of their current psychiatric symptoms have not been characterize...

    Authors: Juan Wang, Yulong Zhang, Zhiwei Liu, Yating Yang, Yi Zhong, Xiaoshuai Ning, Yelei Zhang, Tongtong Zhao, Lei Xia, Feng Geng, Rui Tao, Mei Fan, Zhenhua Ren and Huanzhong Liu

    Citation: BMC Psychiatry 2020 20:410

    Content type: Research article

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  31. Diabetes self-management education programmes are effective in improving health outcomes in the general population with diabetes. However, it is not known if these programmes include people who also have a sev...

    Authors: Anne Coxon, Hayley McBain, Neli Pavlova, Hannah Rowlands and Kathleen Mulligan

    Citation: BMC Psychiatry 2020 20:386

    Content type: Research article

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  32. Amotivation is regarded as a core negative symptom in patients with schizophrenia. There are currently no objective methods for assessing and measuring amotivation in the scientific literature, only a trend to...

    Authors: Y. X. Lin, Li Jun Zhang, Liang Ying and Qiang Zhou

    Citation: BMC Psychiatry 2020 20:344

    Content type: Research article

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  33. Determining the mental capacity of psychiatric patients for making healthcare related decisions is crucial in clinical practice. This meta-review of review articles comprehensively examines the current evidenc...

    Authors: A. Calcedo-Barba, A. Fructuoso, J. Martinez-Raga, S. Paz, M. Sánchez de Carmona and E. Vicens

    Citation: BMC Psychiatry 2020 20:339

    Content type: Research article

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  34. Working memory (WM) refers to the capacity system for temporary storage and processing of information, which is known to depend on the integrity of the prefrontal cortex. Impairment in working memory is a core...

    Authors: Sara Siddi, Antonio Preti, Elvira Lara, Gildas Brébion, Regina Vila, Maria Iglesias, Jorge Cuevas-Esteban, Raquel López-Carrilero, Anna Butjosa and Josep Maria Haro

    Citation: BMC Psychiatry 2020 20:329

    Content type: Research article

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  35. Here we describe a unique case of clozapine-associated hypothermia during initial titration of this medication in an acute inpatient psychiatry setting. Only a handful of cases on this topic have been publishe...

    Authors: Bradley G. Burk, Alex H. Ward and Brooke Clark

    Citation: BMC Psychiatry 2020 20:290

    Content type: Case report

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  36. Schizophrenia spectrum disorders (SSD) are ranked among the leading causes of disabilities worldwide. Many people with SSD spend most of their daily time being inactive, and this is related to the severity of ...

    Authors: Giovanni de Girolamo, Matteo Rocchetti, Ilaria Maria Antonietta Benzi, Sara Agosta, Letizia Casiraghi, Clarissa Ferrari, Nicola De Franceschi, Ambra Macis, Silvia Pogliaghi and Fabrizio Starace

    Citation: BMC Psychiatry 2020 20:287

    Content type: Study protocol

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  37. Violence against patients with schizophrenia is very common, however it is rarely studied in China, especially in primary health care institutions of rural areas. Therefore, we investigated the frequency of vi...

    Authors: Qian-Wen Wang, Cai-Lan Hou, Shi-Bin Wang, Zhuo-Hui Huang, Ying-Hua Huang, Ji-Jie Zhang and Fu-Jun Jia

    Citation: BMC Psychiatry 2020 20:286

    Content type: Research article

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  38. Prior resting state functional Magnetic Resonance Imaging studies (rs-fMRI) via the regional homogeneity (ReHo) method have demonstrated inconsistent and conflicting results because of several confounding fact...

    Authors: Wei Yan, Rongrong Zhang, Min Zhou, Shuiping Lu, Wenmei Li, Shiping Xie and Ning Zhang

    Citation: BMC Psychiatry 2020 20:283

    Content type: Research article

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  39. Systemic inflammation is emerging as an important factor in the etiology of psychiatric disorders such as depression and anxiety. Therefore, the inflammatory potential of the diet may also be an etiological fa...

    Authors: Hamideh Ghazizadeh, Mahdiyeh Yaghooti-Khorasani, Zahra Asadi, Reza Zare-Feyzabadi, Fatemeh Saeidi, Niloofar Shabani, Mahshid Safari-Ghalezou, Mehran Yadegari, Abolfazl Nosrati-Tirkani, Nitin Shivappa, James R. Hébert, Mohsen Moohebati, Gordon A. Ferns, Habibollah Esmaily and Majid Ghayour-Mobarhan

    Citation: BMC Psychiatry 2020 20:282

    Content type: Research article

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  41. QT interval prolongation is a growing concern worldwide, posing psychiatric patients to life-threatening fatal arrhythmias i.e., torsade de pointes. This study aimed to identify the prevalence of QT interval p...

    Authors: Zahid Ali, Mohammad Ismail, Zahid Nazar, Fahadullah Khan, Qasim Khan and Sidra Noor

    Citation: BMC Psychiatry 2020 20:277

    Content type: Research article

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  42. Carers of people with psychosis are at a greater risk of physical and mental health problems compared to the general population. Yet, not all carers will experience a decline in health. This predicament has pr...

    Authors: Cassie M. Hazell, Mark Hayward, Fiona Lobban, Aparajita Pandey, Vanessa Pinfold, Helen E. Smith and Christina J. Jones

    Citation: BMC Psychiatry 2020 20:269

    Content type: Research article

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  44. The self-evaluation of negative symptoms scale (SNS) is a new easy-to-use self-administered questionnaire allowing clinicians to understand the clinical and genetic factors affecting the negative symptoms in p...

    Authors: Aline Hajj, Souheil Hallit, Karam Chamoun, Hala Sacre, Sahar Obeid, Chadia Haddad, Sonia Dollfus and Lydia Rabbaa Khabbaz

    Citation: BMC Psychiatry 2020 20:240

    Content type: Research article

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  45. Conflicting evidence exists on whether parent or spouse caregivers experience better outcomes when caring for family members with schizophrenia. The current study aims to examine relative caregiving experience...

    Authors: Yu Yu, Tong-xin Li, Yi-lu Li, Dan Qiu, Shi-jun Xi, Shui-yuan Xiao and Jacob Kraemer Tebes

    Citation: BMC Psychiatry 2020 20:226

    Content type: Research article

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  46. It has been shown that iron deficiency anemia (IDA) is associated with psychosocial consequences and psychiatric morbidity. However, the association between adults with IDA and psychiatric disorders has not be...

    Authors: Herng-Sheng Lee, Hsin-Hao Chao, Wan-Ting Huang, Solomon Chih-Cheng Chen and Hsin-Yi Yang

    Citation: BMC Psychiatry 2020 20:216

    Content type: Research article

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  47. Patients with psychiatric disorders, such as major depressive disorder, schizophrenia or obsessive-compulsive disorder, often suffer from cognitive dysfunction. The nature of these dysfunctions and their relat...

    Authors: Dorien H. Nieman, UnYoung Chavez-Baldini, Nienke C. Vulink, Dirk J. A. Smit, Guido van Wingen, Pelle de Koning, Arjen L. Sutterland, Roel J. T. Mocking, Claudi Bockting, Karin J. H. Verweij, Anja Lok and Damiaan Denys

    Citation: BMC Psychiatry 2020 20:212

    Content type: Study protocol

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  48. Delirium is common in critically ill patients and it is associated with poor outcomes. In Tunisia, however, it is still underdiagnosed as there is no validated screening tool. The aim of this study was to tran...

    Authors: Imen Ben Saida, Saiid Kortli, Badii Amamou, Nawres Kacem, Mariem Ghardallou, Eugene Wesley Ely, Helmi Ben Saad and Mohamed Boussarsar

    Citation: BMC Psychiatry 2020 20:206

    Content type: Research article

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  49. Patients with a diagnosis of schizophrenia are at an increased risk for developing metabolic syndrome, which is associated with greater cardiovascular morbidity and mortality. Treatment with some commonly used...

    Authors: Greg W. Mattingly, Peter M. Haddad, Michael Tocco, Jane Xu, Debra Phillips, Andrei Pikalov and Antony Loebel

    Citation: BMC Psychiatry 2020 20:199

    Content type: Research article

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  50. Inpatient psychiatric care is a scarce and expensive resource in the National Health Service (NHS), with chronic bed shortages being partly driven by high re-admission rates. Brief inpatient talking therapies ...

    Authors: Pamela Jacobsen, Emmanuelle Peters, Emily J. Robinson and Paul Chadwick

    Citation: BMC Psychiatry 2020 20:193

    Content type: Research article

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