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Psychotic disorders

This section focuses on psychotic disorders. Topics of interest include, but are not limited to, schizophrenia, antipsychotics, biochemistry, hallucinations, delusions, neurocognitive functioning and brain imaging.

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  1. Seventy per cent of patients with psychotic disorders has paranoid delusions. Paranoid delusions are associated with significant distress, hospital admission and social isolation. Cognitive-behavioural therapy...

    Authors: M. Berkhof, E. C. D. van der Stouwe, B. Lestestuiver, E. van’t Hag, R. van Grunsven, J. de Jager, E. Kooijmans, C. E. R. Zandee, A. B. P. Staring, R. M. C. A. Pot-Kolder, M. Vos and W. Veling

    Citation: BMC Psychiatry 2021 21:496

    Content type: Study protocol

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  2. Urban birth and upbringing show consistent associations with psychotic illness but the key urban exposures remain unknown. Associations with psychotic-like experiences (PEs) are inconsistent. These could be co...

    Authors: Jeremy W. Coid, Yamin Zhang, Huan Sun, Hua Yu, Wei Wei, Xiaojing Li, Qiuyue Lv, Wanjie Tang, Qiang Wang, Wei Deng, Wanjun Guo, Liansheng Zhao, Xiaohong Ma, Yajing Meng, Mingli Li, Huiyao Wang…

    Citation: BMC Psychiatry 2021 21:493

    Content type: Research article

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  3. Restless arms syndrome (RAS) is characterized by uncomfortable aching or burning sensations in the arms. RAS is regarded as an upper limb variant of restless legs syndrome (RLS). The lack of specific diagnosti...

    Authors: Juan Chen, Na Meng, Bingrong Cao, Yinghua Ye, Ying Ou and Zhe Li

    Citation: BMC Psychiatry 2021 21:453

    Content type: Case report

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  4. In people with intellectual disability (ID) and challenging behaviour, antipsychotics (AP) are often used off-label and for a long period. Despite a lack of evidence for efficacy for challenging behaviour and ...

    Authors: Sylvie Beumer, Pauline Hamers, Alyt Oppewal and Dederieke Maes-Festen

    Citation: BMC Psychiatry 2021 21:439

    Content type: Study protocol

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  5. Individuals receiving means-tested benefits are at a higher risk of being diagnosed with a psychiatric illness compared to those who are employed, and the rate of those working in the first labor market is low...

    Authors: Felix S. Hussenoeder, Maria Koschig, Ines Conrad, Uta Gühne, Alexander Pabst, Sophie-Elisabeth Kühne, Mathias Alberti, Katarina Stengler and Steffi G. Riedel-Heller

    Citation: BMC Psychiatry 2021 21:410

    Content type: Study protocol

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  6. Cannabis use is an important risk factor for development of psychosis and further transition to schizophrenia. The prevalence of patients with psychosis and comorbid cannabis use (dual diagnosis) is rising wit...

    Authors: Jesper Østrup Rasmussen, Poul Jennum, Kristian Linnet, Birte Y. Glenthøj and Lone Baandrup

    Citation: BMC Psychiatry 2021 21:404

    Content type: Study protocol

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  7. Antibiomania is a rare but recognized side effect with yet unclear definite pathogenesis although multiple hypotheses have been proposed. The novelty of this case is the suspected pharmacodynamic drug-drug int...

    Authors: Edith Paula Meszaros, Catheline Stancu, Alessandra Costanza, Marie Besson, François Sarasin, Guido Bondolfi and Julia Ambrosetti

    Citation: BMC Psychiatry 2021 21:399

    Content type: Case report

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  8. Charles Bonnet Syndrome (CBS) is a rare clinical entity that is classically composed of visual hallucinations in the context of an altered optic pathway with preservation of reality judgment. This case aims to...

    Authors: Lomelín-López Diana, Jaime Carmona-Huerta, J. Guillermo Patiño, Aldana-López Alejandro and Durand-Arias Sol

    Citation: BMC Psychiatry 2021 21:365

    Content type: Case report

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  9. Anti-NMDA receptor encephalitis (NMDAR-E) is an autoimmune encephalitis (AE) mainly affecting young females. It typically presents with isolated psychiatric symptoms (e.g. depressed mood) at first and neurolog...

    Authors: David Weiss, Lisa Kertzscher, Magdalena Degering, David Wozniak and Michael Kluge

    Citation: BMC Psychiatry 2021 21:355

    Content type: Case report

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  10. Severity of symptoms in patients with schizophrenia is a determinant of patient’s well-being, but evidence in low- and middle-income countries is limited. We aimed to measure the symptom severity using objecti...

    Authors: Teerapat Teetharatkul, Arnont Vitayanont, Tippawan Liabsuetrakul and Warut Aunjitsakul

    Citation: BMC Psychiatry 2021 21:348

    Content type: Research article

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  11. Anti-N-methyl-D-aspartate receptor (anti-NMDAR) encephalitis is an autoimmune disorder which often presents with neuropsychiatric symptoms. A large proportion of cases are associated with an identifiable tumor...

    Authors: Khushminder Chahal, Tara Endeman, Sarah Scapinello and Michal Sapieha

    Citation: BMC Psychiatry 2021 21:347

    Content type: Case report

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  12. Research using the integrated model of metacognition has suggested that the construct of metacognition could quantify the spectrum of activities that, if impaired, might cause many of the subjective disturbanc...

    Authors: P. H. Lysaker, S. Cheli, G. Dimaggio, B. Buck, K. A. Bonfils, K. Huling, C. Wiesepape and J. T. Lysaker

    Citation: BMC Psychiatry 2021 21:329

    Content type: Review

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  13. The use of atypical antipsychotics for the treatment of schizophrenia and other mental disorders in populations under 18 years of age is increasing worldwide. Little is known about treatment patterns and the i...

    Authors: Izabela Fulone, Marcus Tolentino Silva and Luciane Cruz Lopes

    Citation: BMC Psychiatry 2021 21:320

    Content type: Research article

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  14. Patients with schizophrenia need continuous integrated healthcare, but many discontinue their treatment, often experiencing adverse outcomes. The first objective of this study is to assess whether patient char...

    Authors: Arnold P. M. van der Lee, Adriaan Hoogendoorn, Lieuwe de Haan and Aartjan T. F. Beekman

    Citation: BMC Psychiatry 2021 21:319

    Content type: Research article

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  15. Schizophrenia and bipolar disorder are serious psychiatric disorders with a high disease burden, a high number of years of life lived with disability and a high risk for relapses and re-hospitalizations. Besid...

    Authors: Ulrike Stentzel, Neeltje van den Berg, Kilson Moon, Lara N. Schulze, Josephine Schulte, Jens M. Langosch, Wolfgang Hoffmann and Hans J. Grabe

    Citation: BMC Psychiatry 2021 21:318

    Content type: Research article

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  16. To understand the implications of switching from paliperidone palmitate 1-monthly (PP1M) to paliperidone palmitate 3-monthly (PP3M) treatment of schizophrenia from the perspective of four key stakeholders: pat...

    Authors: Katalin Pungor, Pedro Sanchez, Sofia Pappa, Jerome Attal, Karolina Leopold, Geertje Steegen, Antonio Vita, Carol Marsella, Caroline Verrijcken, Marjolein Lahaye and Annette Wooller

    Citation: BMC Psychiatry 2021 21:300

    Content type: Research article

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  17. In the population of postmenopausal patients with major depressive disorder (MDD), the superiority of serotonin-norepinephrine reuptake inhibitors (SNRIs) over selective serotonin reuptake inhibitors (SSRIs) h...

    Authors: Jingjing Zhou, Xiao Wang, Lei Feng, Le Xiao, Rui Yang, Xuequan Zhu, Hui Shi, Yongdong Hu, Runsen Chen, Philip Boyce and Gang Wang

    Citation: BMC Psychiatry 2021 21:260

    Content type: Research article

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  18. To investigate a 3-stage screening procedure and explore the clinical features of subjects at Clinical High Risk (CHR) for psychosis in a representative sample of Chinese college students.

    Authors: Jiaxin Wu, Xiangyun Long, Fei Liu, Ansi Qi, Qi Chen, Xiaofeng Guan, Qiong Zhang, Yuhong Yao, Jingyu Shi, Shiping Xie, Wei Yan, Maorong Hu, Xin Yuan, Jun Tang, Siliang Wu, Tianhong Zhang…

    Citation: BMC Psychiatry 2021 21:253

    Content type: Research article

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  19. Assessment of cognitive disorders in schizophrenia is becoming a part of clinical and research practice by using batteries that differ widely in their content. The Brief Assessment of Cognition in Schizophreni...

    Authors: Chadia Haddad, Pascale Salameh, Souheil Hallit, Sahar Obeid, Georges Haddad, Jean-Pierre Clément and Benjamin Calvet

    Citation: BMC Psychiatry 2021 21:223

    Content type: Research article

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  20. This post hoc analysis of clinical trial data evaluated long-term, self-reported mental and physical health-related quality of life (HRQoL) scores in schizophrenia patients receiving aripiprazole lauroxil (AL)...

    Authors: Joseph P. McEvoy, Peter J. Weiden, Paul H. Lysaker, Xiaowu Sun and Amy K. O’Sullivan

    Citation: BMC Psychiatry 2021 21:164

    Content type: Research article

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  21. Perinatal depression is the most common complication of gestation and childbearing affecting women and their families, and good social support and family function are considered protective and modifiable facto...

    Authors: Yilin Huang, Yan Liu, Yu Wang and Danping Liu

    Citation: BMC Psychiatry 2021 21:151

    Content type: Research article

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  22. Patients with schizophrenia are at least twice as likely to develop diabetes mellitus compared to the general population. This is of significance in Qatar given the high prevalence of obesity and diabetes. Fur...

    Authors: Mustafa Abdul Karim, Nadeen Al-Baz, Sami Ouanes, Ali Khalil, Ahmed H. Assar, Abdulkarim Alsiddiqi, Zeinab Dabbous, Mahmoud Zirie, Peter Woodruff, Rayaz A. Malik and Peter M. Haddad

    Citation: BMC Psychiatry 2021 21:149

    Content type: Research article

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  23. Loneliness is an important public health problem with established adverse effects on physical and mental health. Although people with psychosis often experience high levels of loneliness, relatively little is ...

    Authors: Theodora Stefanidou, Jingyi Wang, Nicola Morant, Brynmor Lloyd-Evans and Sonia Johnson

    Citation: BMC Psychiatry 2021 21:134

    Content type: Research article

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  24. The 22q11.2 deletion syndrome (22q11DS) is a genetic syndrome that results in a highly variable profile of affected individuals of which impairments in the social domain and increased psychopathology are the m...

    Authors: Branka Milic, Clémence Feller, Maude Schneider, Martin Debbané and Henriette Loeffler-Stastka

    Citation: BMC Psychiatry 2021 21:130

    Content type: Research article

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  25. In sub-Saharan Africa, common mental disorders (CMDs) like depression and anxiety are under-investigated amongst young people living with HIV (YLWH). To address the gap, in Kenya we: a) determined the prevalen...

    Authors: Moses K. Nyongesa, Paul Mwangi, Michael Kinuthia, Amin S. Hassan, Hans M. Koot, Pim Cuijpers, Charles R. J. C. Newton and Amina Abubakar

    Citation: BMC Psychiatry 2021 21:90

    Content type: Research article

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  26. Neutropenia, a decrease in total number of neutrophils below 1500/mm3 and particularly severe neutropenia, defined as neutrophils less than 500/mm3, is a potential adverse effect of antipsychotic medications that...

    Authors: Natalie Martos, William Hall, Alicia Marhefka, Thomas W. Sedlak and Frederick C. Nucifora Jr

    Citation: BMC Psychiatry 2021 21:76

    Content type: Case report

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  27. Seasonal migrant farmworkers in Ethiopia are a vulnerable segment of the population facing numerous threats to their mental health. This research aimed to determine the magnitude of common mental disorders (CM...

    Authors: Kassahun Alemu Gelaye, Malede Mequanent Sisay, Temesgen Yihunie Akalu, Destaw Fetene Teshome, Haileab Fekadu Wolde, Getu Debalkie Demissie, Sintayehu Daba Wami, Telake Azale and Tadesse Awoke Ayele

    Citation: BMC Psychiatry 2021 21:69

    Content type: Research article

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  28. We aimed to investigate whether females with psychosexual disorders were associated with the risk of affective and other psychiatric disorders. A total of 2240 enrolled individuals, with 560 patients with psyc...

    Authors: Iau-Jin Lin, Nian-Sheng Tzeng, Chi-Hsiang Chung and Wu-Chien Chien

    Citation: BMC Psychiatry 2021 21:63

    Content type: Research article

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  29. Patients with mental illness report lower quality of life (QoL) compared to the general population. Prior research has found several differences in clinical features and experiences of male and female patients...

    Authors: Saleha Shafie, Ellaisha Samari, Anitha Jeyagurunathan, Edimansyah Abdin, Sherilyn Chang, Siow Ann Chong and Mythily Subramaniam

    Citation: BMC Psychiatry 2021 21:61

    Content type: Research article

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  30. Video gaming is a promising intervention for cognitive and social impairment in patients with schizophrenia. A number of gaming interventions have been evaluated in small-scale studies with various patient gro...

    Authors: Maritta Välimäki, Min Yang, Yuen Ting Joyce Lam, Tella Lantta, Matias Palva, Satu Palva, Benjamin Yee, Siu Hung Yip, Kin-sun Dan Yu, Hing Chiu Charles Chang, Po Yee Ivy Cheng and Daniel Bressington

    Citation: BMC Psychiatry 2021 21:46

    Content type: Study protocol

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  31. Fluid intelligence deficits affect executive functioning and social behaviors in patients with schizophrenia. To help clinicians manage fluid intelligence deficits, a psychometrically sound measure is needed. ...

    Authors: Kuan-Wei Chen, Ya-Chen Lee, Tzu-Ying Yu, Li-Jung Cheng, Chien-Yu Chao and Ching-Lin Hsieh

    Citation: BMC Psychiatry 2021 21:39

    Content type: Research article

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  32. Poor adherence and negative attitudes to treatment are common clinical problems when treating psychotic disorders. This study investigated how schizophrenia core symptoms and daily functioning affect treatment...

    Authors: J. Leijala, O. Kampman, J. Suvisaari and S. Eskelinen

    Citation: BMC Psychiatry 2021 21:37

    Content type: Research article

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  33. High rates of psychotropic medications are prescribed in aged care homes despite their limited effectiveness and associated adverse effects. We aim to evaluate the changes in prescription patterns for elderly ...

    Authors: Daya Ram Parajuli, Abraham Kuot, Mohammad Hamiduzzaman, Justin Gladman and Vivian Isaac

    Citation: BMC Psychiatry 2021 21:36

    Content type: Research article

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    The Correction to this article has been published in BMC Psychiatry 2021 21:159

  34. Schizophrenia is associated with widespread cognitive impairment. The MATRICS Consensus Cognitive Battery (MCCB) is most frequently used to assess cognitive function. However, the MCCB test is time consuming f...

    Authors: Bochao Huang, Shangda Li, Bing Sun, Hailong lyu, Weijuan Xu, Jianping Jiao, Fen Pan, Jianbo Hu, Jinkai Chen, Yaping Chen, Manli Huang and Yi Xu

    Citation: BMC Psychiatry 2021 21:21

    Content type: Research article

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  35. Antipsychotic-induced Weight Gain (AiWG) is a debilitating and common adverse effect of antipsychotics. AiWG negatively impacts life expectancy, quality of life, treatment adherence, likelihood of developing t...

    Authors: Nini de Boer, Sinan Guloksuz, Caroline van Baal, Leonie Willebrands, Jeroen Deenik, Christiaan H. Vinkers, Inge Winter-van Rossum, Janneke Zinkstok, Ingeborg Wilting, Jasper B. Zantvoord, Frank Backx, Wilma E. Swildens, Marieke Schouw, Jan Bogers, Folkwin Hulshof, Rudolf de Knijff…

    Citation: BMC Psychiatry 2021 21:4

    Content type: Study protocol

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  36. The time between discharge from hospital and transition to community and home is a critical period for health status among patients with a mental illness, including patients with schizophrenia. This study aime...

    Authors: Anantree Smithnaraseth, Acharaporn Seeherunwong, Rungnapa Panitrat and Mathuros Tipayamongkholgul

    Citation: BMC Psychiatry 2020 20:592

    Content type: Research article

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  37. Electroencephalography (EEG) frontal alpha asymmetry (FAA) has been observed in several psychiatric disorders. Dominance in left or right frontal alpha activity remains inconsistent in patients with major depr...

    Authors: Kuk-In Jang, Chany Lee, Sangmin Lee, Seung Huh and Jeong-Ho Chae

    Citation: BMC Psychiatry 2020 20:586

    Content type: Research article

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  38. Clozapine is an atypical antipsychotic proven to be superior in the treatment of treatment-resistant schizophrenia. Myocarditis is a rare, but well-known complication of treatment with clozapine. Only few case...

    Authors: M. Z. van der Horst, F. van Houwelingen and J. J. Luykx

    Citation: BMC Psychiatry 2020 20:568

    Content type: Case report

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  39. Autoenucleation is a rare form of self-mutilation typically associated with psychiatric disorders such as schizophrenia, substance-induced psychosis and bipolar disorder. The act is usually unilateral, althoug...

    Authors: Natalia Chechko, Eva Stormanns, Klaus Podoll, Susanne Stickel and Irene Neuner

    Citation: BMC Psychiatry 2020 20:563

    Content type: Case report

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  40. The jumping to conclusions bias (JTC) is considered to be an important causal factor in theoretical models for the formation and maintenance of delusions. However, recent meta-analytic findings show a rather e...

    Authors: Nico Pytlik, Daniel Soll, Klaus Hesse, Steffen Moritz, Andreas Bechdolf, Jutta Herrlich, Tilo Kircher, Stefan Klingberg, Martin W. Landsberg, Bernhard W. Müller, Georg Wiedemann, Andreas Wittorf, Wolfgang Wölwer, Michael Wagner and Stephanie Mehl

    Citation: BMC Psychiatry 2020 20:554

    Content type: Research article

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  41. Switching to aripiprazole from other antipsychotics can avoid antipsychotic-induced hyperprolactinemia but may result in an abnormally low prolactin level. This study aimed to assess whether the aripiprazole-i...

    Authors: Ya-Wen Jen, Tzung-Jeng Hwang, Hung-Yu Chan, Ming H. Hsieh, Chen-Chung Liu, Chih-Min Liu, Hai-Gwo Hwu, Ching-Hua Kuo, Yi-Ting Lin, Yi-Ling Chien and Wei J. Chen

    Citation: BMC Psychiatry 2020 20:552

    Content type: Research article

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  42. Over the past decade, antidepressant prescriptions have increased in European countries and the United States, partly due to an increase in the number of new cases of mental illness. This paper demonstrates an...

    Authors: Mark Cherrie, Sarah Curtis, Gergő Baranyi, Stuart McTaggart, Niall Cunningham, Kirsty Licence, Chris Dibben, Clare Bambra and Jamie Pearce

    Citation: BMC Psychiatry 2020 20:551

    Content type: Research article

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  43. Anhedonia is a core clinical symptom of mental disorders. The Revised Physical Anhedonia Scale (RPAS) and the Revised Social Anhedonia Scale (RSAS) have been applied in clinical and non-clinical samples since ...

    Authors: Qiongqiong Wu, Jiayue He, Shulin Fang, Panwen Zhang, Xingwei Luo, Jianghua Zhang, Yan Xiong, Fusheng Luo, Xiaosheng Wang, Shuqiao Yao and Xiang Wang

    Citation: BMC Psychiatry 2020 20:529

    Content type: Research article

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  44. Antipsychotic medications are the first-line pharmacological intervention for severe mental illnesses (SMI) such as schizophrenia and other psychoses, while also being used to relieve distress and treat neurop...

    Authors: A. H. Heald, M. Stedman, S. Farman, C. Khine, M. Davies, M. De Hert and D. Taylor

    Citation: BMC Psychiatry 2020 20:528

    Content type: Research article

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  45. Reluctance on the part of mental health professionals constitutes an important barrier to patient participation in care. In order to stimulate person-centeredness in the inpatient care of persons with psychoti...

    Authors: Katarina Allerby, Anneli Goulding, Lilas Ali and Margda Waern

    Citation: BMC Psychiatry 2020 20:523

    Content type: Research article

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  46. Personal recovery is associated with many significant health-related factors, but studies exploring associations between activity factors and personal recovery among service users are scarce. The aims of this ...

    Authors: Elisabeth Argentzell, Martin Bäckström, Kristine Lund and Mona Eklund

    Citation: BMC Psychiatry 2020 20:520

    Content type: Research article

    Published on:

  47. Erotomania, also known as “de Clérambault’s Syndrome”, is a psychiatric syndrome characterized by the delusional belief that one is loved by another person of, generally of a higher social status. Erotomania h...

    Authors: Maria Teresa Tavares Rodrigues Tomaz Valadas and Lucilia Eduarda Abrantes Bravo

    Citation: BMC Psychiatry 2020 20:516

    Content type: Case report

    Published on:

  48. Psychiatric disorders and ocular neurovascular diseases may share a similar pathophysiological route of vascular structures or neurological changes. The aim of this study is to investigate the association betw...

    Authors: Chun-Hao Liu, Eugene Yu-Chuan Kang, Yu-Hsiang Lin, Wei-Chi Wu, Zhuo-Hao Liu, Chang-Fu Kuo, Chi-Chun Lai and Yih-Shiou Hwang

    Citation: BMC Psychiatry 2020 20:486

    Content type: Research article

    Published on:

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