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Psychotic disorders

This section focuses on psychotic disorders. Topics of interest include, but are not limited to, schizophrenia, antipsychotics, biochemistry, hallucinations, delusions, neurocognitive functioning and brain imaging.

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  1. Despite the potential impact on treatment adherence and recovery, there is a dearth of data on the extent and correlates of internalized stigma in patients with schizophrenia in low income countries. We conduc...

    Authors: Dereje Assefa, Teshome Shibre, Laura Asher and Abebaw Fekadu

    Citation: BMC Psychiatry 2012 12:239

    Content type: Research article

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  2. Metabolic syndrome (MS) is a cluster of the most dangerous cardiac risk factors and is associated with high mortality. Ethnic differences in metabolic syndrome (MS) criteria and prevalence rates have been repo...

    Authors: Waleed M Sweileh, Sa’ed H Zyoud, Salah A Dalal, Sami Ibwini, Ansam F Sawalha and Iyad Ali

    Citation: BMC Psychiatry 2012 12:235

    Content type: Research article

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  3. Studies in developed countries indicate that psychotic-like symptoms are prevalent in the community and are related to trauma exposure and PTSD. No comparable studies have been undertaken in low-income, post-c...

    Authors: Ian Soosay, Derrick Silove, Catherine Bateman-Steel, Zachary Steel, Paul Bebbington, Peter B Jones, Tien Chey, Lorraine Ivancic and Claire Marnane

    Citation: BMC Psychiatry 2012 12:229

    Content type: Research article

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  4. Although persistent negative symptoms (PNS) are known to contribute significantly to poor functional outcome, they remain poorly understood. We examined the heuristic value of various PNS definitions and their...

    Authors: Cindy L Hovington, Michael Bodnar, Ridha Joober, Ashok K Malla and Martin Lepage

    Citation: BMC Psychiatry 2012 12:224

    Content type: Research article

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  5. Little is known about the long-term outcomes for patients with schizophrenia who fail to achieve symptomatic remission. This post-hoc analysis of a 3-year study compared the costs of mental health services and...

    Authors: Virginia S Haynes, Baojin Zhu, Virginia L Stauffer, Bruce J Kinon, Michael D Stensland, Lei Xu and Haya Ascher-Svanum

    Citation: BMC Psychiatry 2012 12:222

    Content type: Research article

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  6. Numerous structurally unrelated drugs, including antipsychotics, can prolong QT interval and trigger the acquired long QT syndrome (aLQTS). All of them are thought to act at the level of KCNH2, a subunit of th...

    Authors: Maciej Jakub Lazarczyk, Zahir A Bhuiyan, Nicolas Perrin and Panteleimon Giannakopoulos

    Citation: BMC Psychiatry 2012 12:220

    Content type: Case report

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  7. With many atypical antipsychotics now available in the market, it has become a common clinical practice to switch between atypical agents as a means of achieving the best clinical outcomes. This study aimed to...

    Authors: Jihyung Hong, Diego Novick, Roberto Brugnoli, Jamie Karagianis, Martin Dossenbach and Josep Maria Haro

    Citation: BMC Psychiatry 2012 12:218

    Content type: Research article

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  8. “Neuroleptic malignant syndrome” (NMS) is a potentially fatal idiosyncratic reaction to any medication which affects the central dopaminergic system. Between 0.5% and 1% of patients exposed to antipsychotics d...

    Authors: Julie Langan, Daniel Martin, Polash Shajahan and Daniel J Smith

    Citation: BMC Psychiatry 2012 12:214

    Content type: Database

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  9. Polydipsia frequently occurs in schizophrenia patients. The excessive water loading in polydipsia occasionally induces a hyponatremic state and leads to water intoxication. Whether polydipsia in schizophrenic ...

    Authors: Tomohisa Nagashima, Makoto Inoue, Soichiro Kitamura, Kuniaki Kiuchi, Jun Kosaka, Koji Okada, Naoko Kishimoto, Toshiaki Taoka, Kimihiko Kichikawa and Toshifumi Kishimoto

    Citation: BMC Psychiatry 2012 12:210

    Content type: Research article

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  10. Antipsychotic drugs are considered a trigger factor for autonomic dysregulation, which has been shown to predict potentially fatal arrhythmias in schizophrenia. However, the dose-dependent effect of antipsycho...

    Authors: Yohko Iwamoto, Chiaki Kawanishi, Ikuko Kishida, Taku Furuno, Mami Fujibayashi, Chie Ishii, Norio Ishii, Toshio Moritani, Masataka Taguri and Yoshio Hirayasu

    Citation: BMC Psychiatry 2012 12:199

    Content type: Research article

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  11. The sole focus of models of insight on bio-medical perspectives to the complete exclusion of local, non-medical and cultural constructs mandates review. This study attempted to investigate the impact of insigh...

    Authors: Shanthi Johnson, Manoranjitham Sathyaseelan, Helen Charles, Visalakshi Jeyaseelan and Kuruthukulangara Sebastian Jacob

    Citation: BMC Psychiatry 2012 12:159

    Content type: Research article

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  12. An appropriate understanding of the association between high-Expressed Emotion (EE) in family members of people with schizophrenia, patients’ and relatives’ correlates is needed to improve adaptation of psycho...

    Authors: Giuseppe Carrà, Carlo Lorenzo Cazzullo and Massimo Clerici

    Citation: BMC Psychiatry 2012 12:140

    Content type: Research article

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  13. Current guidelines suggest specific criteria for oral or long-acting injectable antipsychotic drugs (LAIs). This review aims to describe the demographic and clinical characteristics of the ideal profile of the...

    Authors: Giuseppe Rossi, Sonia Frediani, Roberta Rossi and Andrea Rossi

    Citation: BMC Psychiatry 2012 12:122

    Content type: Research article

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    The Erratum to this article has been published in BMC Psychiatry 2013 13:334

  14. Lack of insight is a core feature of schizophrenia and is associated with structural brain abnormalities. The functional neuroanatomy of insight has only recently been investigated. When people evaluate their ...

    Authors: Nicholas J Bedford, Simon Surguladze, Vincent Giampietro, Michael J Brammer and Anthony S David

    Citation: BMC Psychiatry 2012 12:106

    Content type: Research article

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  15. The authors sought to compare gray matter changes in First Episode Schizophrenia (FES) compared with Fronto-Temporal Lobar Degeneration (FTLD) using meta-analytic methods applied to neuro-imaging studies.

    Authors: Bayanne Olabi, Ian Ellison-Wright, Ed Bullmore and Stephen M Lawrie

    Citation: BMC Psychiatry 2012 12:104

    Content type: Research article

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  16. The ultra high risk state for psychosis has not been studied in young offender populations. Prison populations have higher rates of psychiatric morbidity and substance use disorders. Due to the age profile of ...

    Authors: Darran Flynn, Damian Smith, Luke Quirke, Stephen Monks and Harry G Kennedy

    Citation: BMC Psychiatry 2012 12:100

    Content type: Research article

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  17. To fully assess the various dimensions affected by schizophrenia, clinical trials often include multiple scales measuring various symptom profiles, cognition, quality of life, subjective well-being, and functi...

    Authors: Lei Chen, Glenn Phillips, Joseph Johnston, Bruce J Kinon, Haya Ascher-Svanum, Sara Kollack-Walker, Paul Succop and Dieter Naber

    Citation: BMC Psychiatry 2011 11:203

    Content type: Research article

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  18. The benefits of some second-generation antipsychotics (SGAs) must be weighed against the increased risk for diabetes mellitus. This study examines whether the association between SGAs and diabetes differs by d...

    Authors: Marianne Ulcickas Yood, Gerald N DeLorenze, Charles P Quesenberry Jr, Susan A Oliveria, Ai-Lin Tsai, Edward Kim, Mark J Cziraky, Robert D McQuade, John W Newcomer and Gilbert J L'Italien

    Citation: BMC Psychiatry 2011 11:197

    Content type: Research article

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  19. This observational study explored the prevalence of metabolic syndrome (MetS) in adult in- and outpatients with untreated or treated schizophrenia at baseline, and month-3 after initiation or switch of antipsy...

    Authors: Susanne Kraemer, Anette Minarzyk, Thomas Forst, Daniel Kopf and Hans-Peter Hundemer

    Citation: BMC Psychiatry 2011 11:173

    Content type: Research article

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  20. The Beck Cognitive Insight Scale (BCIS) was designed for the assessment of the cognitive processes involved in self-reflection and the ability to modify erroneous beliefs and misinterpretations. Studies invest...

    Authors: Yu-Chen Kao, Tzong-Shi Wang, Chien-Wen Lu and Yia-Ping Liu

    Citation: BMC Psychiatry 2011 11:170

    Content type: Research article

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  21. Schizophrenia is associated with a two to three fold excess mortality. Both natural and unnatural causes were reported. However, there is dearth of evidence from low and middle income (LAMIC) countries, partic...

    Authors: Solomon Teferra, Teshome Shibre, Abebaw Fekadu, Girmay Medhin, Asfaw Wakwoya, Atalay Alem, Gunnar Kullgren and Lars Jacobsson

    Citation: BMC Psychiatry 2011 11:165

    Content type: Research article

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  22. Low levels of self-esteem have been implicated as both a cause and a consequence of severe mental disorders. The main aims of the study were to examine whether premorbid adjustment has an impact on the subject...

    Authors: Kristin Lie Romm, Jan Ivar Rossberg, Charlotte Fredslund Hansen, Elisabeth Haug, Ole A Andreassen and Ingrid Melle

    Citation: BMC Psychiatry 2011 11:136

    Content type: Research article

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  23. The aim of this study was to determine glutathione levels and antioxidant enzyme activities in the drug-naive first-episode patients with schizophrenia in comparison with healthy control subjects.

    Authors: Monia Raffa, Fatma Atig, Ahmed Mhalla, Abdelhamid Kerkeni and Anwar Mechri

    Citation: BMC Psychiatry 2011 11:124

    Content type: Research article

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