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  1. Content type: Research article

    Little data exists on the effectiveness of psychological interventions for children with posttraumatic stress disorder (PTSD) that has resulted from exposure to war or conflict-related violence, especially in ...

    Authors: Lamaro P Onyut, Frank Neuner, Elisabeth Schauer, Verena Ertl, Michael Odenwald, Maggie Schauer and Thomas Elbert

    Citation: BMC Psychiatry 2005 5:7

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  2. Content type: Research article

    Recent magnetic resonance spectroscopy (MRS) studies report that glutamine is altered in the brains of schizophrenic patients. There were also conflicting findings on glutamate in cerebrospinal fluid (CSF) of ...

    Authors: Kenji Hashimoto, Göran Engberg, Eiji Shimizu, Conny Nordin, Leif H Lindström and Masaomi Iyo

    Citation: BMC Psychiatry 2005 5:6

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  3. Content type: Research article

    Although serotonin reuptake inhibitors are effective in the treatment of OCD, many patients fail to respond to these agents. Growing evidence from open-label and placebo-controlled trials suggests a role for a...

    Authors: Paul D Carey, Bavanisha Vythilingum, Soraya Seedat, Jacqueline E Muller, Michael van Ameringen and Dan J Stein

    Citation: BMC Psychiatry 2005 5:5

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  4. Content type: Research article

    While physical health has improved considerably over recent decades in Finland, the disease burden of mental health, especially that of depression, has become increasingly demanding. However, we lack long-term...

    Authors: Heli Koivumaa-Honkanen, Jaakko Kaprio, Risto J Honkanen, Heimo Viinamäki and Markku Koskenvuo

    Citation: BMC Psychiatry 2005 5:4

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  5. Content type: Research article

    Previous research indicated that women are more vulnerable than men to adverse psychological consequences of weight gain. Other research has suggested that weight gain experienced during antipsychotic therapy ...

    Authors: Haya Ascher-Svanum, Michael Stensland, Zhongyun Zhao and Bruce J Kinon

    Citation: BMC Psychiatry 2005 5:3

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  6. Content type: Research article

    Similarities between obsessive-compulsive disorder (OCD) and trichotillomania (TTM) have been widely recognized. Nevertheless, there is evidence of important differences between these two disorders. Some autho...

    Authors: Christine Lochner, Soraya Seedat, Pieter L du Toit, Daniel G Nel, Dana JH Niehaus, Robin Sandler and Dan J Stein

    Citation: BMC Psychiatry 2005 5:2

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  7. Content type: Research article

    The most prominent feature of melancholic depression is a near-total loss of the capacity to derive pleasure from activities or other positive stimuli. Additional symptoms can include psychomotor disturbances,...

    Authors: Craig H Mallinckrodt, John G Watkin, Chaofeng Liu, Madelaine M Wohlreich and Joel Raskin

    Citation: BMC Psychiatry 2005 5:1

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  8. Content type: Research article

    The Depression Network Study (DeNt) is a multicentre study designed to identify genes and/or loci linked to and/or associated with susceptibility to unipolar depression in Caucasian families. This study presen...

    Authors: Anne Farmer, Gerome Breen, Shyama Brewster, Nick Craddock, Mike Gill, Ania Korszun, Wolfgang Maier, Lefkos Middleton, Ole Mors, Mike Owen, Julia Perry, Martin Preisig, Marcella Rietschel, Theodore Reich, Lisa Jones, Ian Jones…

    Citation: BMC Psychiatry 2004 4:42

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  9. Content type: Research article

    A high frequency of childhood abuse has often been reported in adult psychiatric patients. The present survey explores the relationship between psychiatric diagnoses and positive and negative life events durin...

    Authors: Evangelia Saleptsi, Dana Bichescu, Brigitte Rockstroh, Frank Neuner, Margarete Schauer, Karl Studer, Klaus Hoffmann and Thomas Elbert

    Citation: BMC Psychiatry 2004 4:40

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  10. Content type: Research article

    This study reports on clinical data from an 8-week open-label study of 20 HIV-seropositive individuals, diagnosed with Major Depressive Disorder (DSM-IV), who were treated with SAM-e (S-Adenosylmethionine). SA...

    Authors: R Andrew Shippy, Douglas Mendez, Kristina Jones, Irene Cergnul and Stephen E Karpiak

    Citation: BMC Psychiatry 2004 4:38

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  11. Content type: Research article

    It is well known that most suicide cases meet criteria for a psychiatric disorder. However, rates of specific disorders vary considerably between studies and little information is known about gender and geogra...

    Authors: Geneviève Arsenault-Lapierre, Caroline Kim and Gustavo Turecki

    Citation: BMC Psychiatry 2004 4:37

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  12. Content type: Case report

    Psychiatric sleep research has attempted to identify diagnostically sensitive and specific sleep patterns associated with particular disorders. Both schizophrenia and alcoholism are typically characterized by ...

    Authors: Nina Lindberg, Pekka Tani, Pirjo Takala, Eila Sailas, Hanna Putkonen, Markku Eronen and Matti Virkkunen

    Citation: BMC Psychiatry 2004 4:35

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  13. Content type: Research article

    Political instability and the civil war in Southern Sudan have resulted in numerous atrocities, mass violence, and forced migration for vast parts of the civilian population in the West Nile region. High expos...

    Authors: Frank Neuner, Maggie Schauer, Unni Karunakara, Christine Klaschik, Christina Robert and Thomas Elbert

    Citation: BMC Psychiatry 2004 4:34

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  14. Content type: Research article

    A Mental Health First Aid course has been developed which trains members of the public in how to give initial help in mental health crisis situations and to support people developing mental health problems. Th...

    Authors: Anthony F Jorm, Betty A Kitchener, Richard O'Kearney and Keith BG Dear

    Citation: BMC Psychiatry 2004 4:33

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  15. Content type: Research article

    It has been suggested that infection with Toxoplasma gondii is associated with slow reaction and poor concentration, whilst infection with Coxiella burnetii may lead to persistent symptoms of fatigue.

    Authors: Hollie V Thomas, Daniel Rh Thomas, Roland L Salmon, Glyn Lewis and Andy P Smith

    Citation: BMC Psychiatry 2004 4:32

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  16. Content type: Research article

    The lifetime prevalence of Social Phobia (SP) in European countries other than Italy has been estimated to range from 3.5% to 16.0%. The aim of this study was to assess the frequency of SP in Sardinia (Italy) ...

    Authors: Mauro Giovanni Carta, Maria Carolina Hardoy, Mariangela Cadeddu, Bernardo Carpiniello, Liliana Dell'Osso, Mario Antonio Reda and Hans-Ulrich Wittchen

    Citation: BMC Psychiatry 2004 4:31

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  17. Content type: Research article

    Several studies have now examined the effects of selective serotonin reuptake inhibitor (SSRI) treatment on brain function in a variety of anxiety disorders including obsessive-compulsive disorder (OCD), postt...

    Authors: Paul D Carey, James Warwick, Dana JH Niehaus, Geoffrey van der Linden, Barend B van Heerden, Brian H Harvey, Soraya Seedat and Dan J Stein

    Citation: BMC Psychiatry 2004 4:30

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  18. Content type: Research article

    Depression is frequently occurring during and after psychosis. The aim of this study was to analyze if the psychosocial characteristics associated with depression/depressive symptoms in the late phase of a fir...

    Authors: Yvonne Forsell, Sonja Levander and Johan Cullberg

    Citation: BMC Psychiatry 2004 4:29

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  19. Content type: Research article

    Methylphenidate (MPH) is commonly prescribed in the treatment of Attention-Deficit/Hyperactivity Disorder or ADHD. Concerta and Metadate CD are once-daily formulations of MPH using different delivery mechanism...

    Authors: Edmund JS Sonuga-Barke, James M Swanson, David Coghill, Heleen H DeCory and Simon J Hatch

    Citation: BMC Psychiatry 2004 4:28

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  20. Content type: Research article

    Results obtained from brain imaging studies indicate that serotonin transporter (SERT) and dopamine transporter (DAT) densities are altered in major depression. However, no such studies have been published on ...

    Authors: Tommi Tolmunen, Mikko Joensuu, Pirjo Irmeli Saarinen, Hanna Mussalo, Pasi Ahola, Ritva Vanninen, Jyrki Kuikka, Jari Tiihonen and Johannes Lehtonen

    Citation: BMC Psychiatry 2004 4:27

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  21. Content type: Research article

    A mixed-effects model repeated measures approach (MMRM) was specified as the primary analysis in the Phase III clinical trials of duloxetine for the treatment of major depressive disorder (MDD). Analysis of co...

    Authors: Craig H Mallinckrodt, Joel Raskin, Madelaine M Wohlreich, John G Watkin and Michael J Detke

    Citation: BMC Psychiatry 2004 4:26

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  22. Content type: Research article

    To evaluate the association between mood and anxiety disorders and thyroid autoimmunity in a community sample. Methods: A community based sample of 222 subjects was examined. Psychiatric diagnoses were formula...

    Authors: Mauro Giovanni Carta, Andrea Loviselli, Maria Carolina Hardoy, Sergio Massa, Mariangela Cadeddu, Claudia Sardu, Bernardo Carpiniello, Liliana Dell'Osso and Stefano Mariotti

    Citation: BMC Psychiatry 2004 4:25

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  23. Content type: Research article

    Combining bright light exposure and physical exercise may be an effective way of relieving depressive symptoms. However, relatively little is known about individual factors predicting either a good response or...

    Authors: Sami Leppämäki, Jari Haukka, Jouko Lönnqvist and Timo Partonen

    Citation: BMC Psychiatry 2004 4:22

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  24. Content type: Research article

    The glutamatergic dysfunction hypothesis of schizophrenia suggests that genes involved in glutametergic transmission are candidates for schizophrenic susceptibility genes. We have been performing systematic as...

    Authors: Xiangdong Deng, Hiroki Shibata, Hideaki Ninomiya, Nobutada Tashiro, Nakao Iwata, Norio Ozaki and Yasuyuki Fukumaki

    Citation: BMC Psychiatry 2004 4:21

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  25. Content type: Research article

    Cognitive traits derived from neuropsychological test data are considered to be potential endophenotypes of schizophrenia. Previously, these traits have been found to form a valid basis for clustering samples ...

    Authors: Fabian Hoti, Annamari Tuulio-Henriksson, Jari Haukka, Timo Partonen, Lasse Holmström and Jouko Lönnqvist

    Citation: BMC Psychiatry 2004 4:20

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  26. Content type: Research article

    Current operational diagnostic systems have substantial limitations for lifetime diagnostic classification of bipolar spectrum disorders. Issues include: (1) It is difficult to operationalize the integration o...

    Authors: Nick Craddock, Ian Jones, George Kirov and Lisa Jones

    Citation: BMC Psychiatry 2004 4:19

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  27. Content type: Research article

    Polypharmacy with psychoactive drugs is an increasingly common and debatable contemporary practice in clinical psychiatry based more upon experience than evidence. The objective of this study was to evaluate t...

    Authors: Carlos De las Cuevas and Emilio J Sanz

    Citation: BMC Psychiatry 2004 4:18

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  28. Content type: Research article

    Early intervention teams attempt to improve outcome in schizophrenia through earlier detection and the provision of phase-specific treatments. Whilst the number of early intervention teams is growing, there is...

    Authors: Max Marshall, Austin Lockwood, Shôn Lewis and Matthew Fiander

    Citation: BMC Psychiatry 2004 4:17

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  29. Content type: Research article

    Several studies have suggested an association between the functional Val 158 Met polymorphism in the Catechol-O-Methyltransferase (COMT) gene and neurocognitive performance...

    Authors: Sophie Mills, Kate Langley, Marianne Van den Bree, Eddy Street, Darko Turic, Michael J Owen, Michael C O'Donovan and Anita Thapar

    Citation: BMC Psychiatry 2004 4:15

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  30. Content type: Research article

    Efficient, accurate instruments for measuring depression are increasingly important in clinical practice. We developed a computerized adaptive version of the Beck Depression Inventory (BDI). We examined its ef...

    Authors: William Gardner, Katherine Shear, Kelly J Kelleher, Kathleen A Pajer, Oommen Mammen, Daniel Buysse and Ellen Frank

    Citation: BMC Psychiatry 2004 4:13

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  31. Content type: Research article

    Since the introduction of antipsychotics, especially the so called atypicals, the treatment of schizophrenia has shown important improvements. At the present time, it is preferred to label clozapine and other ...

    Authors: Rogelio Apiquian, Ana Fresán, Camilo de la Fuente-Sandoval, Rosa-Elena Ulloa and Humberto Nicolini

    Citation: BMC Psychiatry 2004 4:12

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  32. Content type: Research article

    The aim of this study was to comprehensively examine clinical risk factors, including suicide intent and hopelessness, for suicide and risk of death from all causes after attempted suicide over a 12-year follo...

    Authors: Kirsi Suominen, Erkki Isometsä, Aini Ostamo and Jouko Lönnqvist

    Citation: BMC Psychiatry 2004 4:11

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  33. Content type: Research article

    Attention-deficit hyperactivity disorder is an early-onset, clinically heterogenous disorder of inattention, hyperactivity, and impulsiveness. The diagnosis and treatment of attention-deficit hyperactivity dis...

    Authors: Shahin Akhondzadeh, Mohammad-Reza Mohammadi and Mojgan Khademi

    Citation: BMC Psychiatry 2004 4:9

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  34. Content type: Research article

    This study examined how ethnic differences in sleep and depression were related to environmental illumination and circadian rhythms.

    Authors: Daniel F Kripke, Girardin Jean-Louis, Jeffrey A Elliott, Melville R Klauber, Katharine M Rex, Arja Tuunainen and Robert D Langer

    Citation: BMC Psychiatry 2004 4:8

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  35. Content type: Research article

    It is unclear why approximately 10% of suicide completers seem to be psychiatrically normal. To better understand this issue, we studied suicide completers without an axis I diagnosis and compared them, on mea...

    Authors: Carl Ernst, Aleksandra Lalovic, Alain Lesage, Monique Seguin, Michel Tousignant and Gustavo Turecki

    Citation: BMC Psychiatry 2004 4:7

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  36. Content type: Research article

    Unipolar depression might be characterized by a 'low-thyroid function syndrome'. To our knowledge, this is the first study which explores the possible relationship of DSM-IV depressive subtypes and the medium ...

    Authors: Konstantinos N Fountoulakis, Apostolos Iacovides, Philippos Grammaticos, George St Kaprinis and Per Bech

    Citation: BMC Psychiatry 2004 4:6

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  37. Content type: Research article

    Severe traumatic stressors such as war, rape, or life-threatening accidents can result in a debilitating psychopathological development conceptualised as Posttraumatic Stress Disorder (PTSD). Pathological memo...

    Authors: Judith Glaesser, Frank Neuner, Ralph Lütgehetmann, Roger Schmidt and Thomas Elbert

    Citation: BMC Psychiatry 2004 4:5

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  38. Content type: Research article

    Concentrations of monoamine metabolites in human cerebrospinal fluid (CSF) have been used extensively as indirect estimates of monoamine turnover in the brain. CSF monoamine metabolite concentrations are partl...

    Authors: Erik G Jönsson, Jessica Bah, Jonas Melke, Rami Abou Jamra, Johannes Schumacher, Lars Westberg, Roland Ivo, Sven Cichon, Peter Propping, Markus M Nöthen, Elias Eriksson and Göran C Sedvall

    Citation: BMC Psychiatry 2004 4:4

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  39. Content type: Research article

    Epidemiological reports about dementia and Alzheimer's disease (AD) in elderly people from developing countries are scarce. Therefore, we sought to determine the prevalences of dementia and AD in a population ...

    Authors: Cosme Alvarado-Esquivel, Ana Berthina Hernández-Alvarado, Rosa Oralia Tapia-Rodríguez, Ángel Guerrero-Iturbe, Karina Rodríguez-Corral and Sergio Estrada Martínez

    Citation: BMC Psychiatry 2004 4:3

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  40. Content type: Research article

    Estimates of the annual prevalence for Obsessive Compulsive Disorder (OCD) were consistent across the international sites range, 1.9% – 2.5%. The nine population surveys, which used Diagnostic Interview Schedu...

    Authors: Mohammad Reza Mohammadi, Ahmad Ghanizadeh, Mehdi Rahgozar, Ahmad Ali Noorbala, Haratoun Davidian, Hossein Malek Afzali, Hamid Reza Naghavi, Seyed Abbas Bagheri Yazdi, Seyed Mehdi Saberi, Bita Mesgarpour, Shahin Akhondzadeh, Javad Alaghebandrad and Mehdi Tehranidoost

    Citation: BMC Psychiatry 2004 4:2

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