Figure 1

CGI-P and CGI-T scores separated according to child's triallelic 5-HTTLPR genotype at three time points (B, P, and M). Conners' global index scores (± SD) for parents (1a) and teachers (1b) in children with ADHD separated according to their genotype in the 5-HTTLPR of the serotonin transporter gene (SLC6A4) during baseline evaluation (B), treatment with placebo (P) and treatment with methylphenidate (M). Dashed line represents the threshold for clinical significance on the Conners' scales (≥ 65). Asterisks indicate the levels of significance of the differences in CGI scores between different assessments (B vs. P and P vs. M). ***: p < 0.001, **: p < 0.01, *: p < 0.05, ns = non significant.