A. | Development of severe muscle rigidity and elevated temperature associated with the use of neuroleptic medication |
B. | Two (or more) of the following |
a. | diaphoresis, |
b. | dysphagia, |
c. | tremor, |
d. | incontinence, |
e. | changes in level of consciousness (ranging from confusion to coma), |
f. | mutism, |
g. | tachycardia, |
h. | elevated or labile blood pressure, |
i. | leukocytosis |
j. | Laboratory evidence of muscle injury (e.g. elevated CPK creatinine phosphokinase). |
C. | The symptoms in criteria A and B are not due to another substance, neurological or general medical condition |
D. | The symptoms in A and B are no better accounted for by a mental disorder |