No interaction between serotonin transporter gene (5-HTTLPR) polymorphism and adversity on depression among Japanese children and adolescents

Table 1 Demographics, early adversity, and clinical characteristics in individuals in patients and healthy controls

	Healthy controls (n = 58)	Patients (n = 55)	t-test, ANOVA, other t(F)-value	P-value
Demographics
Age (years)	13.8 ± 2.1	14.3 ± 1.9	1.21	0.4
Gender (Males/Females)	40 M/18 F	21 M/34 F	Fisher Exact	0.01
Early Adversity	0	11	Fisher Exact	<0.001
Socioeconomic Status	4.1 ± 0.6	4.0 ± 0.7	2.62	0.11
Clinical Characteristics
SDS Score*	36.47 ± 6.19	56.95 ± 6.42	(−235.96)	<0.001
DSRS-C Score*	7.51 ± 4.33	21.92 ± 6.23	(189.03)	<0.001
Full Scale IQ*	109.56 ± 12.15	94.29 ± 16.49	−6.43	0.01
Verbal IQ*	105.74 ± 9.92	89.24 ± 17.37	−9.44	0
Performance IQ*	108.74 ± 10.69	95.78 ± 15.60	7.67	0.01
Verbal Comprehension Index*	109.12 ± 13.00	92.38 ± 22.08	9.05	0
Perceptual Organization*	104.41 ± 11.98	88.90 ± 21.67	4.2	0.04
Freedom from Distractibility*	107.35 ± 12.39	91.7 ± 22.36	3.27	0.08
Processing Speed Index*	109.06 ± 10.50	89.92 ± 25.61	7.99	0.01
Youth Self Report Score (total)	53.9 ± 25.5	84.5 ± 35.9	23.59	<0.001
Youth Self Report Score (internal)	8.3 ± 7.2	25.1 ± 8.3	63.91	<0.001
Youth Self Report Score (external)	10.2 ± 6.7	14.1 ± 8.6	5.46	0.02

* ANCOVA with age and gender as covariates. Values are presented as the mean and SD.
DSRS-C, Birleson Depression Self-Rating Scale for Children.

ISSN: 1471-244X