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Table 1 Articles included in the clinical overview; they have been divided into 4 thematic areas based on 4 research questions: 1. role of illness awareness; 2. role of patients’ willingness; 3. role of psychopathological factors 4. therapist’s role

From: Resistance to treatment and change in anorexia nervosa: a clinical overview

Thematic area

Number of articles

Authors

Number of patients

Diagnoses

Type of study

Denial versus insight of illness

7

Couturier & Lock, [25]

86

AN

Retrospective cohort

Gothelf et al., [26]

281

37 AN;163 other psychiatric disorders; 81 HC

Cross sectional

Konstantakopoulos et al., [27]

75

25 AN; 15 BN; 35 HC

Cross sectional

Konstantakopoulos et al., [28]

72

39 AN; 33 BN

Cross sectional

Schoen et al., [29]

14

AN; BN (no subgroups)

Retrospective cohort

Steinglass et al., [30]

25

AN

Cross sectional

Viglione et al., [31]

38

AN

Cross sectional

Motivation to change

33

Ametller et al., [32]

70

AN

Prospective cohort

Ben Tovim et al., [33]

220

95 AN; 88 BN; 37 EDNOS

Longitudinal cohort

Bewell et al., [34]

127

AN

Prospective cohort

Burket & Hodgin, [35]

72

49 BN; 11 ANBP; 6 EDNOS; 6 ANR

Retrospective cohort

Carter et al., [36]

100

AN

Prospective cohort

Casasnovas et al., [37]

218

58 AN; 95 BN; 65 EDNOS

Cross sectional

Cavedini et al., [38]

38

AN

Prospective cohort

Clausen, [39]

78

35 AN; 30 BN; 13 EDNOS

Prospective cohort

Danner et al., [40]

16

AN

Cross sectional

Darcy et al., [41]

20

AN

Cross sectional

Gale et al., [42]

202

62 BN; 140 AN

Cross sectional

Geller et al., [43]

99

15 ANBP ; 32 ANR ; 41 ANST; 7 BN; 4 BNST

Test validation

Geller et al., [44]

63

24 ANR; 12 ANBP; 21 ANST; 7 BN

Prospective cohort

Geller et al., [45]

128

10 ANR; 9 ANBP; 46 BN; 61 EDNOS

Longitudinal cohort

Herzog et al., [46]

246

61 AN; 95 BN; 90 EDNOS

Prospective cohort

Karlsson et al., [47]

89

AN

Prospective cohort

Konstantakopoulos et al., [28]

72

39 AN; 33 BN

Cross sectional

Lund et al., [48]

79

AN

Prospective cohort

McHugh et al., [49]

65

AN

Prospective cohort

Mewes et al., [50]

100

AN

Prospective cohort

Muñoz et al., [51]

385

61 AN; 47 BN; 245 EDNOS

Prospective cohort

Nordbø et al., [20]

18

AN

Cross sectional

Nordbø et al., [52]

18

AN

Cross sectional

Nordbø et al., [53]

36

AN

Cross sectional

Ricca et al., [54]

103

53 AN; 50 ANST

Prospective cohort

Rieger et al., [55]

44

AN

Test validation

Salbach-Andrae et al., [56]

57

AN

Prospective cohort

Schebendach et al., [57]

47

AN recovered

Prospective cohort

Steinglass et al., [30]

25

AN

Cross sectional

Touyz et al., [58]

  

Debate article

Treasure et al., [59]

  

Debate article

Wade et al., [60]

47

AN

Prospective cohort

Ward et al., [61]

35

22 ANR; 11 ANBP; 2 BN

Cross sectional

Maintaining factors and treatment outcome

22

Castro et al., [62]

158

AN

Prospective cohort

Clausen, [39]

78

35 AN; 30 BN; 13 EDNOS

Prospective cohort

Danielsen & Rø, [63]

50

30 AN; 9 BN; 11 EDNOS

Prospective cohort

Deter et al., [64]

81

AN

Prospective cohort

Fairburn et al., [65]

  

Debate article

Fassino et al., [66]

40

AN

Prospective cohort

Fassino et al., [67]

42

AN

Prospective cohort

Fassino et al., [68]

57

28 AN; 29 BN

Prospective cohort

Federici & Kaplan, [69]

15

AN

Cross sectional

Fichter et al., [18]

103

AN

Prospective cohort

Geller et al., [70]

  

Debate article

Goddard et al., [71]

74

63 AN; 7 BN; 4 EDNOS

Prospective cohort

Helverskov et al., [72]

312

58 AN; 68 EDNOS-AN; 111 BN; 75 EDNOS-BN

Prospective cohort

Hjern et al., [73]

748

AN

Prospective cohort

Löwe et al., [74]

84

AN

Prospective cohort

Salbach-Andrae et al., [56]

57

AN

Prospective cohort

Schmidt & Treasure, [75]

  

Debate article

Signorini et al., [76]

58

AN

Prospective cohort

Steinhausen et al., [77]

60

48 ANR; 6 ANBP; 5 Atypical AN; 1 BN

Prospective cohort

Sutandar-Pinnock et al., [78]

73

AN

Prospective cohort

Treasure & Russell., [10]

  

Debate article

Vrabel et al., [79]

74

13 AN; 37 BN; 24 EDNOS

Prospective cohort

Therapeutic relationship, countertransference, management of treatment resistance

18

Carter et al., [36]

100

AN

Prospective cohort

Darcy et al., [41]

20

AN

Cross sectional

Federici & Kaplan, [69]

15

AN

Cross sectional

Feld et al., [80]

19

8ANR; 4ANBP; 4 BN; 3 EDNOS

Prospective cohort

Forget et al., [81]

  

Debate article

Geller et al., [82]

181

Cases: 3 ANBP; 4 ANR; 22 BN; 28 EDNOS

RCT

Controls:3 ANBP; 4 ANR; 21 BN; 28 EDNOS

Gulliksen et al., [53]

38

AN

Cross sectional

Karlsson et al., [47]

89

AN

Prospective cohort

Masson & Sheeshka, [83]

  

Qualitative interview

Moyers & Rollnick, [84]

  

Debate article

Satir et al., [85]

120 (HP)

 

Cross sectional

Skårderud et al., [24]

  

Debate article

Strober et al., [86]

  

Debate article

Tierney & Fox, [87]

53 (HP)

 

Cross sectional

Tozzi et al., [88]

70

AN

Cross sectional

Treasure et al., [59]

  

Debate article

Vitousek et al., [89]

  

Debate article

Warren et al., [90]

43 (HP)

 

Cross sectional

  1. AN Anorexia Nervosa, BN Bulimia Nervosa, ANR Anorexia Nervosa Restricting subtype, ANBP Anorexia Nervosa Binge-Purging subtype, EDNOS Eating Disorder Not Otherwise Specified, ANST Subthreshold Anorexia Nervosa, BNST Subthreshold Bulimia Nervosa, EDNOS-AN anorexia-like eating disorder not otherwise specified-anorexia nervosa, EDNOS-BN anorexia-like eating disorder not otherwise specified-bulimia nervosa, HC Healthy Controls, HP healthcare practitioners, RCT randomized controlled trial.