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Table 4 Early discontinuation of AD treatment within 180 days after discharge, applying A) The minimum refill method and B) The maximum gap method (50% supply gap)

From: Antidepressant utilization after hospitalization with depression: a comparison between non-Western immigrants and Danish-born residents

 

A. Minimum refill method

B. Maximum gap method

OR (95% CI)

HR (95% CI)

n = 312;events = 41

n = 378;events = 72

Patient characteristic

Model A1

Model A2

Model B1

Model B2

Patient origin

Danish-born residents (ref)

1

 

1

 

1

 

1

 

Non-Western immigrants

1.80 (0.87-3.73)

(p = 0.12)

1.69 (0.79-3.59)

(p = 0.17)

1.46 (0.87-2.45)

(p = 0.15)

1.52 (0.89-2.61)

(p = 0.13)

Sex

Female (ref)

1

 

1

 

1

 

1

 

Male

1.82 (0.93-3.55)

(p = 0.08)

1.90 (0.96-3.76)

(p = 0.06)

1.58 (0.99-2.52)

(p = 0.05)

1.59 (0.99-2.55)

(p = 0.05)

Age

Continuous

0.98 (0.95-1.01)

(p = 0.23)

0.98 (0.95-1.01)

(p = 0.19)

0.99 (0.97-1.01)

(p = 0.17)

0.98 (0.96-1.00)

(p = 0.12)

Annual income 1

<13,405 EUR (ref)

  

1

   

1

 

13,405-26,809 EUR

  

0.73 (0.29-1.81)

(p = 0.93)

  

0.75 (0.40-1.40)

(p = 0.36)

26,810-40,214 EUR

  

0.43 (0.15-1.28)

(p = 0.13)

  

0.57 (0.28-1.18)

(p = 0.13)

≥40,215 EUR

  

0.81 (0.23-2.87)

(p = 0.75)

  

1.24 (0.53-2.87)

(p = 0.62)

  1. AD Antidepressant, EUR Euro, HR Hazard ratio, OR Odds ratio.
  2. Model A1: OR for not refilling a prescription within 180 days after the first prescription, including patient origin, age and sex.
  3. Model A2: OR for not refilling a prescription within 180 days after the first prescription, including patient origin, age, sex and income.
  4. Model B1: HR for not refilling a prescription within the allowed supply gap, including patient origin, age and sex.
  5. Model B2: HR for not refilling a prescription within the allowed supply gap, including patient origin, age, sex and income.
  6. 1100 EURO = 746 Danish Krone (DKK) (November 2012).