Variable | No dementia (n = 410) | Probable dementia (n = 110) | Group comparison p value (chi-square or t-test) |
---|---|---|---|
Age at wave 1 | n = 410 | n = 110 |  |
 -mean age in years (SD) | 79.1 (0.6) | 79.0 (0.6) | 0.610 |
Sex | n = 410 | n = 110 |  |
 -% female | 56.6 | 62.7 | 0.247 |
APOE ɛ4 carrier statusa | n = 404 | n = 110 |  |
 -% carrier APOE ɛ4 | 22.5 | 40.9 | <0.001 |
Age 11 IQ (standardised) | n = 365 | n = 102 |  |
 -mean score (SD) | 100.0 (14.5) | 100.1 (16.1) | 0.948 |
Teeth | n = 410 | n = 110 |  |
 -mean number of teeth (SD) | 9.2 (9.4) | 9.6 (8.9) | 0.706 |
Height | n = 409 | n = 107 |  |
 -mean height in cm (SD) | 163.6 (9.4) | 162.1 (9.2) | 0.144 |
Formal education | n = 409 | n = 109 |  |
 -mean number of years (SD) | 10.9 (2.4) | 11.0 (2.7) | 0.732 |
History of diabetes | n = 410 | n = 110 |  |
 -% positive history | 5.4 | 4.5 | 0.731 |
HbA1c | n = 356 | n = 98 |  |
 -mean HbA1c (SD) | 5.7 (0.8) | 5.7 (0.5) | 0.703 |
History of hypertension | n = 406 | n = 109 |  |
 -% positive history | 42.1 | 34.9 | 0.171 |
Systolic blood pressure | n = 408 | n = 109 |  |
 -mean BP in mmHg (SD) | 168.9 (27.3) | 166.0 (24.8) | 0.315 |
Diastolic blood pressure | n = 408 | n = 109 |  |
 -mean BP in mmHg (SD) | 83.1 (13.2) | 81.8 (12.3) | 0.352 |
Statin use | n = 347 | n = 99 |  |
 -% positive history | 7.5 | 11.1 | 0.250 |
Total serum cholesterol | n = 401 | n = 105 |  |
 -mean (SD) | 5.7 (1.1) | 5.6 (1.1) | 0.891 |
Depression (HADS) | n = 409 | n = 109 |  |
 -mean depression score (SD) | 3.5 (2.3) | 3.5 (2.4) | 0.966 |
BMI | n = 409 | n = 107 |  |
 -mean kg/m2 (SD) | 26.4 (4.2) | 25.4 (4.0) | 0.026 |
Smoking status | n = 410 | n = 109 |  |
 -% current smoker | 8.5 | 2.8 | 0.039 |
Lifetime physical activity | n = 273 | n = 74 |  |
 -mean total lifetime score (SD) | 8.7 (3.1) | 9.5 (3.0) | 0.058 |
Physical effort required in occupation | n = 248 | n = 69 |  |
 -mean score (SD) | 2.1 (0.8) | 2.3 (0.8) | 0.065 |