Is there a linear relationship between the Brief Psychiatric Rating Scale and the Clinical Global Impression-Schizophrenia scale? A retrospective analysis

Table 2 Results of stepwise regression 2.

Positive symptoms (conceptual disorganization, grandiosity, hostility, suspiciousness, hallucinations and excitement)
Variable	Unstandardized β	Standard Error	Standardized β	t	p-Value	95% Confidence Interval
Conceptual disorganization	0.419673^†	0.062355	0.414	6.730	0.000	0.296437 - 0.542909
Hostility	0.247835^†	0.066360	0.208	3.735	0.000	0.116685 - 0.378984
Hallucinations	0.288605^†	0.047700	0.363	6.050	0.000	0.194333 - 0.382877
Constant	1.586381	0.163776		9.686	0.000	1.262703 - 1.910059
Negative symptoms (emotional withdrawal and blunted affect)
Variable	Unstandardized β	Standard Error	Standardized β	t	p-Value	95% Confidence Interval
Emotional withdrawal	0.668840^†	0.069960	0.618	9.560	0.000	0.530592 - 0.807089
Constant	2.624571	0.167903		15.631	0.000	2.292775 - 2.956368
General psychopathological symptoms (somatic concern, anxiety, guilt, tension, bizarre behavior, depressed mood, motor retardation, uncooperativeness, unusual thought content and disorientation)
Variable	Unstandardized β	Standard Error	Standardized β	t	p-Value	95% Confidence Interval
Somatic concern	-0.220833**	0.082965	-0.149	-2.662	0.009	-0.384830 - -0.056837
Anxiety	0.251795^†	0.066748	0.250	3.772	0.000	0.119856 - 0.383734
Motor retardation	0.303597^†	0.078253	0.224	3.880	0.000	0.148916 - 0.458278
Uncooperativeness	0.223711**	0.076051	0.204	2.942	0.004	0.073381 - 0.374041
Unusual thought content	0.350995^†	0.062647	0.386	5.603	0.000	0.227160 - 0.474829
Disorientation	0.244946	0.168480	0.076	1.454	0.148	-0.088087 - 0.577979
Constant	1.430263	0.234066		6.111	0.000	0.967587 - 1.892939

^†p < 0.001 Data for schizophrenic patients (n = 150)
^†p < 0.001 Data for schizophrenic patients (n = 150)
*p < 0.05, **p < 0.01, ^†p < 0.001 Data for schizophrenic patients (n = 150)
Results of backward stepwise regression using small sets of variables based on the three domains of the PANSS (positive symptoms, negative symptoms and general psychopathological symptoms). Within positive symptoms, 'conceptual disorganization', 'hostility' and 'hallucinations' were significantly and positively associated with the CGI-SCH score (p < 0.001); within negative symptoms: 'emotional withdrawal' (p < 0.001); within general psychopathological symptoms: 'anxiety', 'motor retardation', 'uncooperativeness', and 'unusual thought content' were significantly and positively associated with the SCH-SCH score (p < 0.005), and 'somatic concern' was inversely associated with the CGI-SCH score (p < 0.01). F-value < 2.000 as a criterion for removal, multiple regression coefficient and the p value are shown. R-squared was 0.6661 (positive symptoms), 0.3818 (negative symptoms) and 0.6716 (general psychopathological symptoms); all p values of respective analysis of variance were less than 0.001.

ISSN: 1471-244X