Table 1 Baseline characteristics of enrolled patients

Female

55%

67%

0.009

Caucasian

93%

88%

0.038

Mean age, years (SD)

41.7 (12.0)

40.2 (11.5)

0.884

Mean weight, kg (SD)

79.4 (17.3)

82.8 (21.3)

0.048

Smoking status, Yes

47%

41%

At least one comorbid medical condition

35%

40%

Work status:

- employed

38%

36%

- missed work days

47%

36%

Past suicide attempts, Yes

39%

35%

Baseline Illness Severity LS mean (95% CI)

YMRS Total

19.0 (18.2 to 19.8)

19.4 (18.4 to 20.4)

0.524

MADRS Total

14.4 (13.5 to 15.3)

13.5 (12.4 to 14.6)

0.186

BAI Total

14.8 (13.4 to 16.2)

15.3 (13.6 to 17.0)

0.658

SF-12:

- Physical Composite

50.6 (49.2 to 51.9)

50.5 (48.8 to 52.1)

0.930

- Mental Composite

38.5 (37.0 to 39.9)

37.0 (35.3 to 38.7)

0.189

Psychiatric Hospitalizations and Use of Psychiatric Emergency Services

Patients Reporting Use in Last 6 Months

Psychiatric Emergency Room Visits

20%

20%

Inpatient Admissions

21%

21%

Lifetime Inpatient Admissions

65%

61%