Table 1 Patient Demographics, Diagnosis, and Medical History

Age (years; N = 4508)

Gender: Female (N = 4513)

BMI (kg/m²; N = 4503)

Living alone (N = 4261)

Currently unable to work ^a (N = 4321)

Duration of inability to work in the last 12 months (weeks; N = 4140)

Diagnosis by ICD Code (reported by > 5% of patients; N = 4493)

   Moderate depressive episode (F32.1)

   Recurrent depressive disorder, current episode moderate (F33.1)

   Severe depressive episode without psychotic symptoms (F32.2)

   Recurrent depressive disorder, current episode severe without psychotic symptoms (F33.2)

   Depressive episode, unspecified (F32.9)

Age at onset of depression (years; N = 4445)

Time since onset of depression (years; N = 4442)

Any hospitalization during the last 12 months (N = 4485)

Any suicide attempt during the last 12 months (N = 4473)

Any concomitant psychiatric diseases (N = 4501)

   Most common (> 10% of patients) concomitant psychiatric diseases: ^b

   Somatoform disorders

   Anxiety disorders/obsessive-compulsive disorders

   Further psychiatric diseases

History of antidepressant therapy in the last week (N = 4500) yes

   Most common (> 5% of patients) antidepressant therapies:

   Tricyclic antidepressant

   Selective serotonin reuptake inhibitor

   Noradrenergic and specific serotonergic antidepressant

   Selective serotonin and noradrenaline reuptake inhibitor

Patients with overall pain VAS > 30 mm

Any permanent pain medication (N = 4503)

Any on-demand pain medication in the last 12 months (N = 4481)

Any concomitant somatic diseases (N = 4495)

   Most common (> 10% of patients) concomitant somatic diseases: ^b

   Muscle and skeleton diseases

   Hypertension

   Neurologic diseases

   Metabolic diseases

   Gastrointestinal diseases

   Allergies