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Table 2 Simulated data of benzodiazepine dose (mg diazepam equivalents) at follow-up (in each intervention group) to estimate the sample size (see text).

From: Prolonged-release melatonin versus placebo for benzodiazepine discontinuation in patients with schizophrenia: a randomized clinical trial - the SMART trial protocol

Group

N

Not transformed

Mean (SD)

Square root transformed

Mean (SD)

Placebo

99

2.81 (2.50)

1.51 (0.73)

Melatonin

99

1.09 (1.18)

0.91 (0.52)

Baseline dose

 

8.79 (6.50)

2.74 (1.13)

  1. SD: Standard deviation.