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Table 1 Clinical characteristics of subjects

From: Restraint of appetite and reduced regional brain volumes in anorexia nervosa: a voxel-based morphometric study

Variable AN (n = 14)
Mean ± SEM
HC (n = 21)
Mean ± SEM
AN v. HC
t-value
AN v. HC
p-value
RAN (n = 8)
Mean ± SEM
BPAN (n = 6)
Mean ± SEM
RAN v. BPAN
t-value
RAN v. BPAN
p-value
Age, years 26 ± 1.9 26 ± 2.1 0.16 ns 26 ± 2.9 27 ± 2.6 0.9 ns
BMI at scan, kg/m 2 15.6 ± 0.4 21.4 ± 0.5 8.4 <0.01 15.1 ± 0.5 16.2 ± 0.3 1.7 ns
Lowest lifetime BMI, kg/m 2 12.4 ± 0.3 19.6 ± 0.3 10.6 <0.01 11.7 ± 0.4 13.4 ± 0.4 2.9 0.01
Education (from 11 yrs old), years 7.2 ± 0.6 11.5 ± 1.4 2.4 0.02 6.8 ± 0.6 7.8 ± 1.0 0.9 ns
Duration Illness, years 9.2 ± 1.9 -- -- -- 9.2 ± 3.1 9.2 ± 2.2 0 ns
EDE-Q (0-6), restrained eating 3.0 ± 0.5 1 ± 0.2 4.9 <0.01 2 ± 0.5 4 ± 0.7 1.8 ns
EDE-Q (Q8) No. of binges month (0-6)* 1 ± 0.5 -- -- -- -- 4 ± 0.8 -- --
EDE-Q (Q22), No. of vomits in month 5.8 ± 1.6 -- -- -- -- 8 ± 2.5 -- --
HADS- Anxiety (0-21) 13.9 ± 0.8 4.4 ± 0.6 9.5 <0.01 13 ± 1.2 15.2 ± 1.0 1.3 ns
HADS- Depression (0-21) 10.3 ± 1.2 1.6 ± 0.4 7.8 <0.01 8.8 ± 1.8 12.3 ± 1.5 1.5 ns
  1. AN = Anorexia Nervosa, HC = Healthy Control, RAN = Restricting Anorexia Nervosa, BPAN = Binge Purge Anorexia Nervosa, SEM = Standard Error Mean, BMI = Body Mass Index, EDE-Q = Eating Disorder Examination Questionnaire, HADS = Hospital Anxiety and Depression Scale, ns = non significant, *an average score of 1 on the EDE-Q, Question 8, represents binges on 1-5 days per month, whereas an average score of 4 represent binges on 16-22 days per month