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Table 2 Univariate and propensity score-stratified models: Hazard Ratio (HR) and its corresponding 95% confidence interval (CI) for risk factors associated with relapse (n = 183).

From: Relapse according to antipsychotic treatment in schizophrenic patients: a propensity-adjusted analysis

 

Patients with relapse

(n = 50)

Patients with no relapse

(n = 133)

 

Propensity score-stratified model

 

M

(SD)1

M

(SD)

P value

HR

(95% CI)

Socio-demographic characteristics

       

Gender (male), N (%)2

34

(68.0)

95

(72.0)

0.60

-

-

Age

36.3

(9.7)

39.9

(10.6)

0.04

-

-

Living conditions (Alone), N (%)

12

(24.0)

53

(39.9)

0.04

-

-

Clinical characteristics

       

Age at onset of illness

21.5

(5.6)

25.4

(8.4)

<0.01

-

-

Total PANSS3 score

66.4

(18.7)

67.4

(20.2)

0.76

-

-

   Positive PANSS score

14.6

(5.4)

13.6

(5.5)

0.26

-

-

   Negative PANSS score

17.7

(6.5)

19.0

(7.8)

0.31

-

-

   General Psychopathology PANSS score

34.0

(10.9)

34.8

(10.5)

0.66

-

-

GAF4 score

51.9

(14.2)

53.3

(15.2)

0.58

-

-

GARF5 score

54.2

(15.9)

55.5

(17.5)

0.64

-

-

SOFAS6 score

52.0

(14.4)

52.9

(14.4)

0.72

-

-

CDSS7 score

3.9

(4.5)

2.8

(3.3)

0.11

-

-

Medication

       

Drugs for side-effects, N (%)

19

(38.0)

63

(47.4)

0.26

-

-

Sedatives drugs, N (%)

31

(62.0)

64

(48.1)

0.09

-

-

Antidepressants, N (%)

13

(26.0)

25

(18.8)

0.28

-

-

AIMS8

2.7

(4.3)

2.9

(4.4)

0.82

-

-

BAS9

1.1

(2.0)

1.0

(2.0)

0.74

-

-

SAS10

3.2

(3.1)

3.3

(3.8)

0.81

-

-

ROMI11

     

-

-

Compliance score

12.9

(2.6)

12.4

(2.8)

0.20

  

Non compliance score

14.5

(3.8)

14.0

(3.7)

0.40

  

Number of previous hospitalisations

7.7

(7.2)

5.7

(5.5)

0.10

  

Quality of life:SF-36

       

Physical Functioning

83.3

(18.8)

78.8

(22.3)

0.23

-

-

Role-Physical Limitations

66.5

(39.1)

72.7

(34.6)

0.32

-

-

Bodily Pain

69.4

(27.6)

73.4

(26.4)

0.39

-

-

General Health

55.8

(22.5)

59.1

(20.8)

0.38

-

-

Vitality

51.5

(16.6)

49.3

(29.4)

0.50

-

-

Mental Health

61.9

(19.5)

62.1

(19.4)

0.96

-

-

Role-Emotional Limitations

63.2

(39.1)

71.5

(38.0)

0.22

-

-

Social Functioning

68.6

(27.7)

68.2

(29.0)

0.93

-

-

Polypharmacy

23

(46.0)

46

(34.6)

0.15

1.686

(0.812; 2.505)

  1. 1 Mean (Standard Deviation)
  2. 2 Effective (Percentage)
  3. 3 Positive and Negative Syndrome Scale; 4Global Assessment Functioning; 5Global Assessment of Relational Functioning; 6Social and Occupational Functioning Assessment Scale; 7Calgary Depression Scale for Schizophrenia; 8Abnormal Involuntary Movement Score; 9Barnes Akathisia score; 10Simpson-Angus score; 11Rating of Medication Influences Scale.
  4. Values significant at the 5% level are marked in bold.