Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive processing in posttraumatic stress disorder

Table 2 Allele and genotype frequencies for SLC6A4 polymorphisms

polymorphism	genotypes	genotype sample size	group sizes [control,PTSD]⁴	minor allele frequency	HWE Χ²	p-value	include genotypes
rs9903602	GG; GT; TT	6, 9, 27	2,4; 3,6; 12,15	.178	7.7	.005	exclude
rs9896947	CC, CT, TT	28, 14, 0	13,15; 7,7; 0,0	.833	1.68	.20	CC,CT
rs9303628	AA; AG;GG	6, 16, 20	3,3; 10,6; 7,13	.333	.86	.35	AG, GG
rs7212502	AA; AG; GG	38, 4, 0	20,18; 2,2; 0,0	.952	.105	.75	exclude
rs4583306	AA; AG; GG	17, 18, 7	10,7; 7,11; 3,4	.619	.350	.55	AA, AG
rs4251417	CC; CT; TT	36, 6, 0	18,18; 2,4; 0,0	.929	.25	.68	exclude
rs3813034	AA; AC; CC	14, 16, 12	9,5; 7,9; 4,8	.274	2.34	.13	exclude
rs2020936	AA, AG, GG	23, 17, 2	9,14; 10,7; 1,1	.750	.265	.61	AA, AG
rs16965628 ³	CC; CG; GG	0, 15, 27	0,0; 8,7; 13,14	.179	1.98	.18	CG, GG
rs16965623	AA; AG; GG	37, 5, 0	18,19; 2,3; 0,0	.940	.170	.68	exclude
rs140701 ³	CC; CT; TT	11, 21, 10	7,4; 8,13; 5,6	.512	.000	.99	CT, TT
rs12150214	CC; CG; GG	3, 17, 22	1,2; 11,16; 8,14	.274	.013	.91	CG, GG
rs11080122	CC; CT; TT	26, 16, 0	10,16; 10,6; 0,0	.810	2.33	.13	CC, CT
triallelic 5-LTTLPR ³	SS,SL_G,L_GL_G; SL_A,L_GL_A; L_AL_A	15, 18, 9	10,5; 6,12; 6;3	.571	.656	.42	SS,SL_G,L_GL_G; SL_A,L_GL_A;
biallelic 5-HTTLPR ³	SS; SL; LL	10, 20, 12	3,7; 12,8; 5,7	.476	.087	.77	S carriers, LL

³polymorphisms with a priori hypothesis
⁴group sizes are reported the number of control and PTSD subjects for each of three genotypes, listed in the order [homozygous, heterozygous, homozygous] and secondarily alphabetical order of coding bases (A, C, G, T).
Abbreviations: Hardy-Weinberg Equilibrium (HWE)

ISSN: 1471-244X