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Table 3 Group comparison for self and other evaluation: all traits combined (see Figure 1 )

From: Self-evaluation in schizophrenia: an fMRI study with implications for the understanding of insight

Cerebral region Peak talairach coordinates x, y, z(range) 3-D Cluster size (in voxels) Significance level
Healthy Controls (HC) > Schizophrenia patients (Sz)
Left Superior Frontal Gyrus, BA9 -6, 53, 32(x: -6 - -14, y: 30–53, z: 22-42; includes BA 8) 153 p = 0.0006
Left Inferior Frontal Gyrus, BA44/45 -48, 16, 16(x: -41 - -48, y: -4–16, z: 9–16; includes insula) 73 p = 0.0027
Left Superior Frontal Gyrus, BA6 -6, 25, 54 20 p = 0.0081#
Schizophrenia patients (Sz) > Healthy Controls (HC)
Right Middle Frontal Gyrus, BA6 Right Middle Frontal Gyrus, BA45 35, -1, 40(x: 29–37, y: -1 –19, z: 40-54; includes BA 8, 9) 121 p = 0.0005
  51, 27, 8(x: 38–49, y: 5–41, z: -7 –29; includes BA 46,47) 148  
Left Middle Temporal Gyrus, BA21 -58, -26, -7 26 p = 0.0083#
  1. #Failed to reach significance after adjustment for cluster level analysis.
  2. BA: Brodmann Area.