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Table 3 Group comparison for self and other evaluation: all traits combined (see Figure 1 )

From: Self-evaluation in schizophrenia: an fMRI study with implications for the understanding of insight

Cerebral region

Peak talairach coordinates x, y, z(range)

3-D Cluster size (in voxels)

Significance level

Healthy Controls (HC) > Schizophrenia patients (Sz)

Left Superior Frontal Gyrus, BA9

-6, 53, 32(x: -6 - -14, y: 30–53, z: 22-42; includes BA 8)

153

p = 0.0006

Left Inferior Frontal Gyrus, BA44/45

-48, 16, 16(x: -41 - -48, y: -4–16, z: 9–16; includes insula)

73

p = 0.0027

Left Superior Frontal Gyrus, BA6

-6, 25, 54

20

p = 0.0081#

Schizophrenia patients (Sz) > Healthy Controls (HC)

Right Middle Frontal Gyrus, BA6 Right Middle Frontal Gyrus, BA45

35, -1, 40(x: 29–37, y: -1 –19, z: 40-54; includes BA 8, 9)

121

p = 0.0005

 

51, 27, 8(x: 38–49, y: 5–41, z: -7 –29; includes BA 46,47)

148

 

Left Middle Temporal Gyrus, BA21

-58, -26, -7

26

p = 0.0083#

  1. #Failed to reach significance after adjustment for cluster level analysis.
  2. BA: Brodmann Area.