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Table 2 Levels of [3 H]DAMGO (mean ± SEM) binding in subjects with schizophrenia, major depressive disorder, bipolar disorder or no history of psychiatric disorder who did or did not die as a result of suicide

From: Mu opioid receptor availability in people with psychiatric disorders who died by suicide: a case control study

Group BA 24 Sample size [3 H]DAMGO binding (fmole/mg ETE) Analysis parameters P value
Suicide 41 32.25 ± 1.76 t = 2.7, df = 120 (non-suicide) 0.008
Non-suicide 81 38.34 ± 1.34   
Diagnosis/suicide BA 24    
Controls 51 37.63 ± 1.83   
Suicides 9 34.02 ± 3.80 t = 0.88 (controls) n.s
MDD 5 27.95 ± 9.06 t = 1.84 (controls) n.s
MDD (suicide) 15 35.69 ± 2.84 t = 0.58 (controls) n.s
BP 8 50.51 ± 1.98 t = 3.00 (controls) n.s
BP (suicide) 5 35.38 ± 3.07 t = 0.43 (controls) n.s
Schizophrenia 26 37.80 ± 1.83 t = 0.04 (controls) n.s
Schizophrenia (suicide) 12 25.31 ± 3.17 t = 3.39 (controls) t = 3.21 (schizophrenia) <0.05
Schizophrenia/suicide BA 9    
Controls 20 31.65 ± 2.11   
Schizophrenia 26 34.40 ± 1.32 t = 1.15 (controls) n.s
Schizophrenia (suicide) 12 24.12 ± 2.27 t = 2.57 (controls) t = 3.68 (schizophrenia) <0.05 <0.05
  CPu    
Controls 20 25.40 ± 2.16   
Schizophrenia 24 23.72 ± 1.37 t = 0.67 (controls) n.s
Schizophrenia (suicide) 11 16.29 ± 2.42 t = 2.97 (controls) t = 2.50 (schizophrenia) <0.05 <0.05
  1. The group comparison the analysis factors refer to is given in brackets below the parameters. Abbreviations: n.s. = not significant.