| |
Patients n (%)
| |
|---|
|
Characteristic (%)
|
Remained (N = 843)
|
Discontinued (N = 339)
|
Total (N = 1182)
|
p-value
|
|---|
|
Geographic Region
| | | |
0.129
|
|
Western Europe
|
148 (68.8)
|
67 (31.2)
|
215
| |
|
Eastern Europe
|
237 (75.2)
|
78 (24.8)
|
315
| |
|
Americas
|
380 (69.1)
|
170 (30.9)
|
550
| |
|
Other
|
78 (76.5)
|
24 (23.5)
|
102
| |
|
Gender
| | | |
0.391
|
|
Female
|
274 (69.7)
|
119 (30.3)
|
393
| |
|
Male
|
569 (72.1)
|
220 (27.9)
|
789
| |
|
EPS
| | | |
0.180
|
|
No
|
542 (74.0)
|
190 (26.0)
|
732
| |
|
Yes
|
113 (68.9)
|
51 (31.1)
|
164
| |
|
Working Status
| | | |
0.003
|
|
Unemployed disab.
|
349 (70.2)
|
148 (29.8)
|
497
| |
|
Paid work
|
181 (81.2)
|
42 (18.8)
|
223
| |
|
Retired
|
101 (82.1)
|
22 (17.9)
|
123
| |
|
Keeping house
|
73 (70.2)
|
31 (29.8)
|
104
| |
|
Unemployed unrel.
|
61 (81.3)
|
14 (18.7)
|
75
| |
|
Student
|
33 (89.2)
|
4 (10.8)
|
37
| |
|
Volunteer
|
23 (69.7)
|
10 (30.3)
|
33
| |
|
Self-employed
|
15 (78.9)
|
4 ( 21.1)
|
19
| |
|
Baseline Remission
| | | | |
|
Cross-sectional
|
455 (74.6)
|
155 (25.4)
|
610
|
0.010
|
|
Mean (SD)
| | | | |
|
Age [year]
|
39.4 (11.43)
|
40.1 (10.89)
|
39.6 (11.28)
|
0.293
|
|
PANSS Total
|
61.4 (16.20)
|
64.1 (16.66)
|
62.1 (16.37)
|
0.012
|
|
PANSS POS
|
2.1 (0.66)
|
2.3 (0.77)
|
2.1 (0.70)
|
<0.001
|
|
PANSS NEG
|
2.4 (0.83)
|
2.4 (0.83)
|
2.4 (0.83)
|
0.969
|
|
PANSS DIS
|
2.1 (0.66)
|
2.2 (0.68)
|
2.1 (0.67)
|
0.274
|
|
PANSS HOS
|
1.5 (0.62)
|
1.7 (0.70)
|
1.6 (0.65)
|
0.003
|
|
PANSS DEP
|
1.9 (0.70)
|
2.0 (0.71)
|
1.9 (0.70)
|
0.015
|
|
QLS Total
|
1.8 (1.84)
|
1.4 (1.73)
|
1.7 (1.81)
|
0.001
|
|
QLS Interpersonal relations
|
2.8 (1.19)
|
2.7 (1.19)
|
2.8 (1.19)
|
0.074
|
|
QLS Instrumental role funct
|
2.5 (1.49)
|
2.2 (1.45)
|
2.4 (1.49)
|
<0.001
|
|
CGI-S
|
3.0 (0.93)
|
3.3 (0.97)
|
3.1 (0.95)
|
<0.001
|
|
No. of previous episodes
|
1.4 (1.53)
|
1.8 (2.74)
|
1.5 (1.91)
|
0.121
|
-
CGI-S: Clinical Global Impression – Severity, EPS: extrapyramidal symptoms, PANSS: Positive and Negative Symptoms Score, QLS: Heinrich Carpenter’s Quality of Life Scale, SD: standard deviation.
