| Before switching | After switching | ||
---|---|---|---|---|
 | OLZ-RIS (n=162) | RIS-OLZ (n=136) | OLZ-RIS (n=162) | RIS-OLZ (n=136) |
Dose (Mean ± SD) | 10.1±5.3 | 4.7±3.0 | 4.6±3.2 | 10.9±5.9 |
Reason for discontinuation (%) a | Â | Â | Â | Â |
  Lack of efficacy | 41.3 | 59.1 | 36.0 | 34.0 |
  Intolerability | 29.7 | 31.8 | 15.7 | 20.0 |
  Lack of compliance | 19.4 | 23.5 | 19.1 | 16.0 |
  Patient request | 34.8 | 28.8 | 19.1 | 26.0 |