Group | Age, Sex | Diagnosis | Psychotic symptoms | Epileptic attack | EEG, sleep symptoms | Treatments | Others | Labolatory for NMDAR antibodies measurements | References |
---|---|---|---|---|---|---|---|---|---|
1(A) encephalitis group | 18/F | anti-NMDAR encephalitis | talkativeness, hyperactivity, bizzare behavoir | generalized tonic-clonic seizure | normal | steroid pulse therapy | slight high density inside the bilateral temporal regions (FLAIR, T2) | Dr Dalmau (University of Pennsylvania) | [14] |
2(A) encephalitis group | 24/M | anti-NMDAR encephalitis | delusion, catalepsy, palilalia | generalized tonic-clonic seizure | 11Hz, alpha wave, (after stroid pulse therapy) | steroid pulse therapy | Â | Dr Dalmau (University of Pennsylvania) | [15] |
3(A) encephalitis group | 27/F | anti-NMDAR encephalitis | substupor, catatonia | unspecified seizure | normal | antipyschotics, m-ECT | after m-ECT, ataxia, nystagmus and agraphia were pointed out | Dr Tanaka(Kanazawa Medical University) | Â |
N(A) type antibody-negative (n=2) | 59/F, 25/M | Limbic encephalitis suspected | stupor, catatonia, hyperactivity, bizzare behavoir,reference delusion | generalized tonic-clonic seizure (n=1) | spike and wave complex (n=1), diffuse slow alpha wave (n=2) | antipyschotics, m-ECT (n=1) | prodromal ful-like symptoms (n=1) | Â | Â |
4(B) narcolepsy with psychosis group | 61/M | Narcolepsy, Parkinson's disease, Delusional disorder(297.1)(F22.0) | visual hallucination, persecutory delusion, delusion of jealousy | (-) | short sleep latency, sleep onset REM periods | antipyschotics, m-ECT | resting tremor, hypocretin deficient narcolepsy | Dr Tanaka(Kanazawa Medical University) | |
5(B) narcolepsy with psychosis group | 37/F | Narcolepsy, Schizophrenia(Paranoid type 295.30)(F20.0) | visual and auditory hallucinations, delusion | (-) | short sleep latency, sleep onset REM periods | antipyschotics | hypocretin deficient narcolepsy | Dr Tanaka(Kanazawa Medical University) | Â |
6(B) narcolepsy with psychosis group | 24/F | Narcolepsy, Schizophrenia(Paranoid type 295.30)(F20.0) | auditory hallucination, delusion, agitation, aggression, | (-) | short sleep latency, sleep onset REM periods | antipyschotics | hypocretin deficient narcolepsy | Dr Tanaka(Kanazawa Medical University) | Â |
N(B) type antibody-negative (n=2) | 25/F, 35/M | Narcolepsy and psychosis (25/F)(298.9)(F29), Narcolepsy and Schizophrenia (35/M)(F20.1)(295.10) | agitation, aggression, auditory hallucination | (-) | short sleep latency, sleep onset REM periods | antipyschotics | hypocretin deficient narcolepsy | Â | Â |
7(C) psychiatric sympotoms | 53/F | Schizophrenia(Catatonic type:295.20)(F20.24), Mental Reterdation(F71.0) | premenstrual tension, atypical pyschosis | generalized tonic-clonic seizure | normal | antipyschotics, m-ECT | Â | Dr Tanaka(Kanazawa Medical University) | Â |
8(C) psychiatric sympotoms | 34/F | Schizoaffective disorder(295.70)(bipolar type:F25.0) | delusion, auditory hallucination, talkativeness, hyper activity, aggression | complex partial seizure | normal | valproic acid | reccurent ovarian cyst, operations were performed | Dr Tanaka(Kanazawa Medical University) | Â |
9(C) psychiatric sympotoms | 30/F | Schizophrenia(Disorganized type:295.10)(F20.12) | acoustic hyperesthesia, irritation | (-) | normal | antipyschotics, m-ECT | oral dyskinesia | Dr Tanaka(Kanazawa Medical University) | [18] |
10(C) psychiatric sympotoms | 26/F | Schizophrenia(Catatonic type:295.20)(F20.25) | hallucination, delusion, depressive mood, hyper activity | (-) | normal | antipyschotics, m-ECT | ovarian tumor, operation was performed | Dr Dalmau (University of Pennsylvania) | [19] |
N(C) type antibody-negative (n=47) | 15-72y, M:F=10:37 | Schizophrenia(295.30,295.20)(F20.0.F20.2), Schizoaffective disorder(295.70), brief psychotic disorder(298.8)(F23.1) | hallucination, delusion, depressive mood, hyper activity, bizzare behavoir, catatonia | generalized tonic-clonic seizure (n=10) | abnormal EEG (n=6) | antipyschotics, m-ECT | ovarian tumor (n=6), convulsion&ovarian tumor (n=2) | Â | Â |