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Table 2 Secondary efficacy measures

From: Efficacy and safety of olanzapine for treatment of patients with bipolar depression: Japanese subpopulation analysis of a randomized, double-blind, placebo-controlled study

Baseline-to-endpoint change Placebo Olanzapine p Value
  (n = 52) (n = 104)  
  LS Mean (SE) LS Mean (SE)  
CGI-BP    
 Depression −0.89 (0.16) −1.41 (0.11) .008
 Mania 0.03 (0.04) 0.01 (0.03) .68
 Bipolar −0.83 (0.15) −1.31 (0.11) .01
HAMD-17 total −7.88 (1.04) −11.66 (0.74) .004
YMRS total 0.34 (0.24) −0.32 (0.17) .03
  1. Abbreviations: CGI-BP = Clinical Global Impressions-Bipolar Version Severity of Illness; HAMD-17 = Hamilton Depression Rating Scale-17 items; LS mean = least squares mean; SE = standard error; YMRS = Young Mania Rating Scale.
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