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Table 1 Baseline demographics and characteristics

From: Comparably high retention and low relapse rates in different subpopulations of bipolar patients in a German non-interventional study

Variable

Total sample N = 761

OM N = 186

LM N = 152

AM N = 216

OLC N = 47

OAC N = 68

OMS N = 44

OC N = 48

Continuous variables

mean (SD)

mean (SD)

mean (SD)

mean (SD)

mean (SD)

mean (SD)

mean (SD)

mean (SD)

Age [years]

48.0 (12.7)

47.8 (13.4)

50.5 (13.5)

46.4 (12.2)

48.9 (11.1)

48.0 (13.0)

44.8 (12.3)

49.7 (9.1)

BMI [kg/m2]

26.9 (4.7)

26.4 (4.2)

26.6 (4.2)

27.4 (5.5)

27.5 (4.1)

26.9 (4.9)

25.8 (3.7)

27.4 (4.9)

Age at first symptoms [years]

31.3 (11.5)

31.5 (11.2)

32.9 (12.7)

30.4 (11.4)

32.4 (10.1)

31.3 (10.5)

28.4 (11.6)

31.5 (11.4)

BP-episodes since start of disease [mean (SD) median]

15.5 (97.6) 6*

8.3 (16.8) 5

8.6 (9.3) 6

10.2 (11.7) 7

10.4 (10.4) 6

8.2 (7.4) 6

8.9 (6.7) 7.5

111.1 (378.7) 10*

No. of manic episodes within last 12 months

1.1 (1.2)

1.1 (1.0)

0.9 (1.2)

0.9 (1.1)

1.0 (1.2)

1.2 (1.1)

1.7 (1.5)

1.5 (1.6)

No. of depressive episodes within last 12 months

1.7 (1.3)

1.7 (1.3)

1.5 (1.3)

1.7 (1.3)

1.6 (1.4)

1.6 (1.4)

1.9 (1.3)

2.4 (1.6)

No. of mixed episodes within last 12 months

0.8 (1.3)

0.7 (1.2)

0.5 (0.9)

0.7 (1.2)

0.8 (1.4)

0.8 (1.1)

1.1 (1.6)

1.7 (2.0)

Time on mood stabilizing therapy [years]

3.9 (4.5)

2.1 (1.4)

6.7 (6.1)

2.9 (2.4)

6.1 (6.3)

2.7 (1.8)

2.5 (2.9)

7.2 (7.8)

Binary variables

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

n (%)

Sex, male

327 (43.0)

86 (46.2)

73 (48.0)

75 (34.7)

29 (61.7)

31 (45.6)

16 (36.4)

17 (35.4)

Paid employment

264 (34.7)

61 (33.2)

49 (32.9)

84 (39.6)

18 (38.3)

24 (36.9)

14 (32.6)

14 (29.2)

Stable social environment

678 (89.1)

165 (89.7)

141 (94.0)

193 (91.0)

45 (95.7)

55 (84.6)

39 (90.7)

40 (83.3)

Rapid cycling

76 (10.0)

15 (8.9)

17 (11.7)

20 (9.5)

0 (0.0)

6 (9.8)

4 (9.3)

14 (33.3)

Hospitalized due to psychiatric disease (last 12 months)

277 (36.4)

71 (38.2)

46 (30.3)

75 (34.7)

20 (42.6)

25 (36.8)

20 (45.5)

20 (41.7)

Further psychiatric diseases

220 (28.9)

55 (30.4)

37 (26.2)

66 (31.1)

10 (21.7)

12 (17.7)

22 (51.2)

18 (39.1)

Alcohol consumption

267 (35.1)

53 (28.5)

67 (44.1)

71 (32.9)

18 (38.3)

20 (29.4)

18 (40.9)

20 (41.7)

Alcohol abuse or addiction

31 (4.07)

8 (1.05)

6 (0.79)

6 (0.79)

3 (0.39)

2 (0.26)

1 (0.13)

5 (0.66)

Illicit drug use

20 (2.6)

2 (1.1)

6 (3.9)

8 (3.7)

2 (4.3)

0 (0)

2 (4.5)

0 (0)

History of suicide attempts

193 (25.4)

40 (21.5)

46 (30.3)

46 (21.3)

8 (17.0)

22 (32.4)

13 (29.5)

18 (37.5)

  1. Abbreviations: BMI body mass index, BP bipolar, SD standard deviation, OM olanzapine monotherapy, LM llithium monotherapy, AM anticonvulsant monotherapy, OLC olanzapine-lithium combination therapy, OAC olanzapine-anticonvulsant combination therapy, OMS other mood stabilizing therapy, OC other combinations, N number of patients.
  2. *High mean and SD due to ultra rapid-cycling patient with 2000 episodes confirmed by investigator.