Skip to main content

Table 1 Baseline demographics and characteristics

From: Comparably high retention and low relapse rates in different subpopulations of bipolar patients in a German non-interventional study

Variable Total sample N = 761 OM N = 186 LM N = 152 AM N = 216 OLC N = 47 OAC N = 68 OMS N = 44 OC N = 48
Continuous variables mean (SD) mean (SD) mean (SD) mean (SD) mean (SD) mean (SD) mean (SD) mean (SD)
Age [years] 48.0 (12.7) 47.8 (13.4) 50.5 (13.5) 46.4 (12.2) 48.9 (11.1) 48.0 (13.0) 44.8 (12.3) 49.7 (9.1)
BMI [kg/m2] 26.9 (4.7) 26.4 (4.2) 26.6 (4.2) 27.4 (5.5) 27.5 (4.1) 26.9 (4.9) 25.8 (3.7) 27.4 (4.9)
Age at first symptoms [years] 31.3 (11.5) 31.5 (11.2) 32.9 (12.7) 30.4 (11.4) 32.4 (10.1) 31.3 (10.5) 28.4 (11.6) 31.5 (11.4)
BP-episodes since start of disease [mean (SD) median] 15.5 (97.6) 6* 8.3 (16.8) 5 8.6 (9.3) 6 10.2 (11.7) 7 10.4 (10.4) 6 8.2 (7.4) 6 8.9 (6.7) 7.5 111.1 (378.7) 10*
No. of manic episodes within last 12 months 1.1 (1.2) 1.1 (1.0) 0.9 (1.2) 0.9 (1.1) 1.0 (1.2) 1.2 (1.1) 1.7 (1.5) 1.5 (1.6)
No. of depressive episodes within last 12 months 1.7 (1.3) 1.7 (1.3) 1.5 (1.3) 1.7 (1.3) 1.6 (1.4) 1.6 (1.4) 1.9 (1.3) 2.4 (1.6)
No. of mixed episodes within last 12 months 0.8 (1.3) 0.7 (1.2) 0.5 (0.9) 0.7 (1.2) 0.8 (1.4) 0.8 (1.1) 1.1 (1.6) 1.7 (2.0)
Time on mood stabilizing therapy [years] 3.9 (4.5) 2.1 (1.4) 6.7 (6.1) 2.9 (2.4) 6.1 (6.3) 2.7 (1.8) 2.5 (2.9) 7.2 (7.8)
Binary variables n (%) n (%) n (%) n (%) n (%) n (%) n (%) n (%)
Sex, male 327 (43.0) 86 (46.2) 73 (48.0) 75 (34.7) 29 (61.7) 31 (45.6) 16 (36.4) 17 (35.4)
Paid employment 264 (34.7) 61 (33.2) 49 (32.9) 84 (39.6) 18 (38.3) 24 (36.9) 14 (32.6) 14 (29.2)
Stable social environment 678 (89.1) 165 (89.7) 141 (94.0) 193 (91.0) 45 (95.7) 55 (84.6) 39 (90.7) 40 (83.3)
Rapid cycling 76 (10.0) 15 (8.9) 17 (11.7) 20 (9.5) 0 (0.0) 6 (9.8) 4 (9.3) 14 (33.3)
Hospitalized due to psychiatric disease (last 12 months) 277 (36.4) 71 (38.2) 46 (30.3) 75 (34.7) 20 (42.6) 25 (36.8) 20 (45.5) 20 (41.7)
Further psychiatric diseases 220 (28.9) 55 (30.4) 37 (26.2) 66 (31.1) 10 (21.7) 12 (17.7) 22 (51.2) 18 (39.1)
Alcohol consumption 267 (35.1) 53 (28.5) 67 (44.1) 71 (32.9) 18 (38.3) 20 (29.4) 18 (40.9) 20 (41.7)
Alcohol abuse or addiction 31 (4.07) 8 (1.05) 6 (0.79) 6 (0.79) 3 (0.39) 2 (0.26) 1 (0.13) 5 (0.66)
Illicit drug use 20 (2.6) 2 (1.1) 6 (3.9) 8 (3.7) 2 (4.3) 0 (0) 2 (4.5) 0 (0)
History of suicide attempts 193 (25.4) 40 (21.5) 46 (30.3) 46 (21.3) 8 (17.0) 22 (32.4) 13 (29.5) 18 (37.5)
  1. Abbreviations: BMI body mass index, BP bipolar, SD standard deviation, OM olanzapine monotherapy, LM llithium monotherapy, AM anticonvulsant monotherapy, OLC olanzapine-lithium combination therapy, OAC olanzapine-anticonvulsant combination therapy, OMS other mood stabilizing therapy, OC other combinations, N number of patients.
  2. *High mean and SD due to ultra rapid-cycling patient with 2000 episodes confirmed by investigator.