Table 1 Descriptive characteristics from 23 studies on the role of theT102C polymorphism of the 5HTR2A gene in suicidal behavior
From: Association of the 5HTR2A gene with suicidal behavior: CASE-control study and updated meta-analysis
Study (Year) | Sample Size n (Cases-Controls) | Location | Diagnosis | Number of C alleles | Gender (males/females) | Mean age (years) | ||
|---|---|---|---|---|---|---|---|---|
Cases | Controls | Cases | Controls | |||||
Tan (2002) | 47/94 | Singapore | SA with schizophrenia | 32 | 47 | 94 | ||
Pooley (2003) | 129/329 | United Kingdom Caucasians | SA | 154 | 52/77 | 138/191 | 38 | 38 |
Chen (2001) | 471/523 | Hong Kong | SA with schizophrenia | 193 | 314 | 308/215 | ||
Saiz (2008) | 193/420 | Asturias in Northern Spain | SA | 196 | 70/123 | 216/204 | 35 | 40 |
Du (2000) | 42/131 | Ottowa | SA with major depression | 99 | 48/30 | 61/70 | 40 | 36 |
Wrsozek (2011) | 38/118 | Polish Caucasians | SA with alcohol-dependent | 33 | 26/12 | 81/29 | >18 | >18 |
Khait (2005) | 52/63 | European Caucasians | SA with depression | 54 | 30/24 | 12/51 | 37 | 40 |
Correa (2007) | 42/85 | Brazilian | SA with schizophrenia | 83 | 23/19 | 45/40 | ||
Vaquero-Lorenzo (2008) | 441/410 | Spanish Caucasians | SA | 472 | 161/280 | 237-173 | 38 | 36 |
Du (1999) | 24/31 | Budapest, Hungary | SC with depression | 32 | 24 | 31 | 45 | 50 |
Bondy (2000) | 131/125 | Caucasians Germany | SA with major depression | 142 | 91/40 | 60/75 | 46 | 47 |
Zhang (2008) | 297/303 | Shangai | SA with schizophrenia, anxiety and organic mental disorder | 229 | 171/126 | 217/112 | 46 | 43 |
Preuss (2000) | 45/117 | Caucasians Germany | SA with alcohol-dependence | 52 | 45 | 56/61 | 47 | |
Preuss (2000) | 62/117 | Caucasians Germany | SI with alcohol-dependence | 66 | 62 | 56/61 | 47 | |
Ertugrul (2004) | 71/26 | Caucacians and African-americans | SA with schizophrenia | 49 | 26/12 | 81/29 | ||
Crawford (2000) | 78/131 | Caucasians Australian | SC | 73 | 68 | 95 | ||
Crawford (2000) | 68/95 | Caucasians Australian | SI | 99 | 78 | 131 | ||
Turecki (1999) | 56/126 | Montreal | SC | 68 | 56 | 126 | 36 | 33 |
Ono (2001) | 151/163 | Japanese | SC | 157 | 106/45 | 108/55 | 47 | 47 |
Zhang (1997) | 15/150 | Japanese | SA with mood disorders | 21 | 15 | 65/85 | 33 | 37 |
Tsai (1999) | 61/96 | Taipei | SA with mood disorders | 49 | 61 | 96 | 71 | |
Arias (2001) | 33/164 | Spanish | SA | 42 | 33 | 83/71 | 55 | 41 |
Tovilla (2012) | 161/244 | Mexican | SA | 220 | 61/100 | 82/162 | 25 | 33 |