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Table 3 Gene expression (mean ± SE) for genes differing between all patients with Depressive Disorders (DD) versus Controls (CON)

From: Dysregulation of leukocyte gene expression in women with medication-refractory depression versus healthy non-depressed controls

GENE CON (n=19) DD (n=23) p valueA p valueB Cohen’s dC
    Log transformed Raw data  
APP 5.65E-01 ± 3.12E-02 6.70E-01 ± 3.59E-02 0.043 0.029 0.661
IL-10 3.86E-03 ± 3.66E-04 5.27E-03 ± 5.33E-04 0.045 0.039 0.655
IL-6 2.02E-03 ± 2.79E-04 2.94E-03 ± 3.45E-04 0.028 0.045 0.719
OXTR 2.94E-03 ± 3.00E-04 4.75E-03 ± 6.95E-04 0.079 0.037 0.569
P2RX7 4.64E-02 ± 3.22E-03 5.84E-02 ± 4.89E-03 0.042 0.050 0.663
P2RY1 7.48E-02 ± 3.89E-03 9.45E-02 ± 5.82E-03 0.015 0.015 0.801
TRPV1 1.15E-02 ± 6.36E-04 1.35E-02 ± 5.07E-04 0.019 0.010 0.777
  1. Raw data is displayed in the table. Expressed in scientific notation units where E+00 = x1, E-01 = x0.1, E-02 = x0.01, etc. Data were log transformed prior to analysis.
  2. ADifferences between DD vs. CON examined using log transformed data and Student’s t-test.
  3. BDifferences between DD vs. CON examined using non-transformed data and nonparametric Wilcoxon Rank Sum test.
  4. All comparisons had 40 degrees of freedom and F values ranging from 4.29 – 6.42.
  5. CCohen d effect sizes were all moderate to large and are reported with DD as the reference group.