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Table 1 Detailed descriptive data of patients with schizophrenia and healthy controls

From: Association of the Hermansky–Pudlak syndrome type 4 (HPS4) gene variants with cognitive function in patients with schizophrenia and healthy subjects

  Schizophrenia (n = 240) Controls (n = 240) z/χ 2 P-value
  Mean (SD) Mean (SD)   
Age (years) 48.1 (12.4) 48.0 (13.0) -0.03 0.98
Sex (male, %)1 57.9 59.6 0.14 0.71
Education (years) 11.7 (2.1) 14.2 (2.3) -10.85 <0.001
Smokers (%)1 38.3 27.9 5.88 0.015
JART 92.4 (10.4) 103.4 (10.7) -10.19 <0.001
Age at onset (years) 24.8 (8.9)
Antipsychotics (mg/day)2 12.7 (9.4)
Anticholinergics (mg/day)3 3.3 (4.2)
Anxiolytics/hypnotics (%) 75.4
PANSS     
Positive score 14.1 (5.3)
Negative score 21.9 (6.7)
General score 33.9 (9.5)
Total 69.0 (18.8)
BACS-J scores     
Verbal memory -2.01 (1.31) 0.00 (1.00) -14.63 <0.001
Working memory -1.95 (1.22) 0.00 (1.00) -14.67 <0.001
Motor speed -1.48 (1.26) 0.00 (1.00) -12.42 <0.001
Verbal fluency -1.15 (1.14) 0.00 (1.00) -10.62 <0.001
Attention -1.97(1.14) 0.00 (1.00) -15.41 <0.001
Executive function -1.77 (2.26) 0.00 (1.00) -9.67 <0.001
Composite Score -1.72 (1.10) 0.00 (0.67) -15.86 <0.001
  1. P-values were analyzed using Mann–Whitney U-tests, except for 1 χ 2 tests. P-values < 0.05 are in bold.
  2. 2Haloperidol equivalent dosage.
  3. 3Biperiden equivalent dosage.
  4. BACS-J: Brief Assessment of Cognition in Schizophrenia, Japanese-language version.
  5. JART: Japanese version of the National Adult Reading Test.
  6. PANSS: Positive and Negative Symptom Scale.