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Table 1 Detailed descriptive data of patients with schizophrenia and healthy controls

From: Association of the Hermansky–Pudlak syndrome type 4 (HPS4) gene variants with cognitive function in patients with schizophrenia and healthy subjects

 

Schizophrenia (n = 240)

Controls (n = 240)

z/χ 2

P-value

 

Mean (SD)

Mean (SD)

  

Age (years)

48.1 (12.4)

48.0 (13.0)

-0.03

0.98

Sex (male, %)1

57.9

59.6

0.14

0.71

Education (years)

11.7 (2.1)

14.2 (2.3)

-10.85

<0.001

Smokers (%)1

38.3

27.9

5.88

0.015

JART

92.4 (10.4)

103.4 (10.7)

-10.19

<0.001

Age at onset (years)

24.8 (8.9)

Antipsychotics (mg/day)2

12.7 (9.4)

Anticholinergics (mg/day)3

3.3 (4.2)

Anxiolytics/hypnotics (%)

75.4

PANSS

    

Positive score

14.1 (5.3)

Negative score

21.9 (6.7)

General score

33.9 (9.5)

Total

69.0 (18.8)

BACS-J scores

    

Verbal memory

-2.01 (1.31)

0.00 (1.00)

-14.63

<0.001

Working memory

-1.95 (1.22)

0.00 (1.00)

-14.67

<0.001

Motor speed

-1.48 (1.26)

0.00 (1.00)

-12.42

<0.001

Verbal fluency

-1.15 (1.14)

0.00 (1.00)

-10.62

<0.001

Attention

-1.97(1.14)

0.00 (1.00)

-15.41

<0.001

Executive function

-1.77 (2.26)

0.00 (1.00)

-9.67

<0.001

Composite Score

-1.72 (1.10)

0.00 (0.67)

-15.86

<0.001

  1. P-values were analyzed using Mann–Whitney U-tests, except for 1 χ 2 tests. P-values < 0.05 are in bold.
  2. 2Haloperidol equivalent dosage.
  3. 3Biperiden equivalent dosage.
  4. BACS-J: Brief Assessment of Cognition in Schizophrenia, Japanese-language version.
  5. JART: Japanese version of the National Adult Reading Test.
  6. PANSS: Positive and Negative Symptom Scale.