Brain responses to body image stimuli but not food are altered in women with bulimia nervosa

Van den Eynde, Frederique; Giampietro, Vincent; Simmons, Andrew; Uher, Rudolf; Andrew, Chris M; Harvey, Philippe-Olivier; Campbell, Iain C; Schmidt, Ulrike

doi:10.1186/1471-244X-13-302

BMC Psychiatry

Table 5 Body image paradigm: group map activations in the bulimia nervosa (BN) and healthy control (HC) groups, and between-group differences in brain activation patterns for the contrast ‘body vs non-body’

From: Brain responses to body image stimuli but not food are altered in women with bulimia nervosa

	p-value	Brodmann Area (BA)	Talairach coordinates	Cluster size (voxels)
People with BN
*Body image > Non-Body*
Left Thalamus	< 0.001	-	x = -21.7; y = -29.6; z = 6.6	131
R Medial Frontal Gyrus	0.002	9	x = 25.3; y = 37.0; z = 9.9	56
L Anterior Cingulate	< 0.001	32	x = -18.1; y = 33.3; z = 13.2	163
R Inferior Frontal Gyrus	< 0.001	9	x = 46.9; y = 7.4; z = 26.4	217
L Precentral Gyrus	< 0.001	6	x = -50.6; y = 0.0; z = 29.7	78
R Inferior Temporal Gyrus	< 0.001	19	x = -46.9; y = -62.9; z = -3.3	1078
R Fusiform Gyrus	< 0.001	37	x = 43.3; y = -59.3; z = -6.6	1662
*Non-Body > Body image*
L Insula	< 0.001	13	x = -32.5; y = 18.5; z = 6.6	301
R Superior Temporal Gyrus	0.002	22	x = 50.6; y = -48.2; z = 16.5	55
R Parahippocampal Gyrus	< 0.001	14	x = 25.3; y = -40.7; z = -9.9	4119
HCs
*Body image > Non-Body*
L Subcallosal Gyrus	0.003	25	x = -3.6; y = 3.7; z = -9.9	50
R Substantia Nigra	0.004	-	x = 18.1; y = -18.5; z = -6.6	49
R Thalamus, Dorsal Nucleus	0.006	-	x = 3.6; y = -18.5; z = 13.2	40
L Precentral Gyrus	0.005	9	x = -39.7; y = 3.7; z = 33.0	43
R Middle Temporal Gyrus	< 0.001	37	x = 43.3; y = -63.0; z = -3.3	1587
L Fusisform Gyris	< 0.001	37	x = -43.3; y = -63.0; z = -6.6	1011
R Inferior Frontal Gyrus	< 0.001	9	x = 43.3; y = 7.4; z = 29.7	318
*Non-Body > Body image*
L Limbic Lobe, Uncus	< 0.001	28	x = -32.5; y = 3.7; z = -23.1	271
R Middle Temporal Gyrus	0.002	39	x = 39.7; y = -70.4; z = 23.1	88
L Parahippocampal Gyrus	< 0.001	36	x = -25.3; y = -37.0; z = -13.2	7408
*People with BN vs HCs*
*People with BN > HCs*
None
*HCs > People with BN*
L Fusiform Gyrus	0.002	37	x = -43.3; y = 63.0; z = -6.6	143
R Middle Temporal Gyrus	< 0.001	37	x = 43.3; y = 63.0; z = 3.3	245

The Talairach coordinates indicate the location of the peak voxel within each cluster.

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ISSN: 1471-244X

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